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Enhancement of the heat conduction performance of boron nitride/cellulosic fibre insulating composites

draft: Zhihuai Yu. Data curation: Zhihuai Yu, Xiu Wang, Liang Jiao, Weibing Wu. 8 / 10 Writing ? review & editing: Huiyang Bian, Weibing Wu. 9 / 10 1. Chowdhury Z , Zain S , Sharifah B ( 2014

De novo characterization of microRNAs in oriental fruit moth Grapholita molesta and selection of reference genes for normalization of microRNA expression

MicroRNAs (miRNAs) are a group of endogenous non-coding small RNAs that have critical regulatory functions in almost all known biological processes at the post-transcriptional level in a variety of organisms. The oriental fruit moth Grapholita molesta is one of the most serious pests in orchards worldwide and threatens the production of Rosacea fruits. In this study, a de novo...

Minimally invasive (sinus tarsi) approach for calcaneal fractures

Background According to the anatomic characteristics of the calcaneus and the sinus tarsi approach, we designed a combined plate. The goal of this study was to retrospectively assess the functional outcomes and complications of treatment with our self-designed plate. Methods From March 2014 to October 2015, 18 patients with closed calcaneal fractures (14 Sanders type II and 4...

Total synthesis of atropurpuran

Gong, Huan Chen, Xiao-Yu Liu, Zhi-Xiu Wang, Wei Nie & Yong Qin AuthorsSearch for Jing Gong in:Nature Research journals • PubMed • Google ScholarSearch for Huan Chen in:Nature Research journals • PubMed ... • Google ScholarSearch for Xiao-Yu Liu in:Nature Research journals • PubMed • Google ScholarSearch for Zhi-Xiu Wang in:Nature Research journals • PubMed • Google ScholarSearch for Wei Nie in:Nature Research

Comparative study of titrated oral misoprostol solution and vaginal dinoprostone for labor induction at term pregnancy

Objective To evaluate effectiveness and safety of titrated oral misoprostol solution (OMS) in comparison with vaginal dinoprostone for cervix ripening and labor induction in term pregnant women. Methods A multicenter randomized controlled trial of women with term singleton pregnancy with indications for labor induction; 481 participants were allocated to receive titrated OMS with...

Predictive Value of Cumulative Blood Pressure for All-Cause Mortality and Cardiovascular Events

The predictive value of cumulative blood pressure (BP) on all-cause mortality and cardiovascular and cerebrovascular events (CCE) has hardly been studied. In this prospective cohort study including 52,385 participants from the Kailuan Group who attended three medical examinations and without CCE, the impact of cumulative systolic BP (cumSBP) and cumulative diastolic BP (cumDBP...

Risk Factors for Postoperative Fibrinogen Deficiency after Surgical Removal of Intracranial Tumors

Higher levels of fibrinogen, a critical element in hemostasis, are associated with increased postoperative survival rates, especially for patients with massive operative blood loss. Fibrinogen deficiency after surgical management of intracranial tumors may result in postoperative intracranial bleeding and severely worsen patient outcomes. However, no previous studies have...

Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer

3-Bromopyruvate (3BP) is an energy-depleting drug that inhibits Hexokinase II activity by alkylation during glycolysis, thereby suppressing the production of ATP and inducing cell death. As such, 3BP can potentially serve as an anti-tumorigenic agent. Our previous research showed that 3BP can induce apoptosis via AKT /protein Kinase B signaling in breast cancer cells. Here we...

Extracellular signal-regulated kinase (ERK) activation is required for itch sensation in the spinal cord

Background Itch, chronic itch in particular, can have a significant negative impact on an individual’s quality of life. However, the molecular mechanisms underlying itch processing in the central nervous system remain largely unknown. Results We report here that activation of ERK signaling in the spinal cord is required for itch sensation. ERK activation, as revealed by anti...

Neurochemical characterization of pERK-expressing spinal neurons in histamine-induced itch

, Bing Lang, David St Clair & Colin McCaigDepartment of Anesthesiology, East Hospital, Tongji University School of Medicine, Shanghai 200120, ChinaMeng-Han Dai, Kun Huang, Guo-Dong Chai & Qing-Xiu Wang ... in:Nature Research journals • PubMed • Google ScholarSearch for Bing Lang in:Nature Research journals • PubMed • Google ScholarSearch for Qing-Xiu Wang in:Nature Research journals • PubMed • Google

Pathological Alterations and Stress Responses near DBS Electrodes after MRI Scans at 7.0T, 3.0T and 1.5T: An In Vivo Comparative Study

Objective The purpose of this study was to investigate the pathological alterations and the stress responses around deep brain stimulation (DBS) electrodes after magnetic resonance imaging (MRI) scans at 7.0T, 3.0T and 1.5T. Materials and Methods DBS devices were stereotactically implanted into the brains of New Zealand rabbits, targeting the left nucleus ventralis posterior...

A mouse line for inducible and reversible silencing of specific neurons

Background Genetic methods for inducibly and reversibly inhibiting neuronal activity of specific neurons are critical for exploring the functions of neuronal circuits. The engineered human glycine receptor, called ivermectin (IVM)-gated silencing receptor (IVMR), has been shown to possess this ability in vitro. Results Here we generated a mouse line, in which the IVMR coding...

Global Identification of Prokaryotic Glycoproteins Based on an Escherichia coli Proteome Microarray

Glycosylation is one of the most abundant protein posttranslational modifications. Protein glycosylation plays important roles not only in eukaryotes but also in prokaryotes. To further understand the roles of protein glycosylation in prokaryotes, we developed a lectin binding assay to screen glycoproteins on an Escherichia coli proteome microarray containing 4,256 affinity...

Species-specific and needle age-related responses of photosynthesis in two Pinus species to long-term exposure to elevated CO2 concentration

There is, so far, no common conclusion about photosynthetic responses of trees to long-term exposure to elevated CO2. Photosynthesis and specific leaf area (SLA) of 1-year-old and current-year needles in Pinus koraiensis and P. sylvestriformis grown in open-top chambers were measured monthly for consecutive two growing seasons (2006, 2007) after 8–9 years of CO2 enrichment in...

Soil Respiration in Relation to Photosynthesis of Quercus mongolica Trees at Elevated CO2

Knowledge of soil respiration and photosynthesis under elevated CO2 is crucial for exactly understanding and predicting the carbon balance in forest ecosystems in a rapid CO2-enriched world. Quercus mongolica Fischer ex Ledebour seedlings were planted in open-top chambers exposed to elevated CO2 (EC = 500 µmol mol−1) and ambient CO2 (AC = 370 µmol mol−1) from 2005 to 2008. Daily...

Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution

Background The fungus Marssonina brunnea is a causal pathogen of Marssonina leaf spot that devastates poplar plantations by defoliating susceptible trees before normal fall leaf drop. Results We sequence the genome of M. brunnea with a size of 52 Mb assembled into 89 scaffolds, representing the first sequenced Dermateaceae genome. By inoculating this fungus onto a poplar hybrid...

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

Background Substantial data indicate that the oncogene microRNA 21 (miR-21) is significantly elevated in glioblastoma multiforme (GBM) and regulates multiple genes associated with cancer cell proliferation, apoptosis, and invasiveness. Thus, miR-21 can theoretically become a target to enhance the chemotherapeutic effect in cancer therapy. So far, the effect of downregulating miR...

Preparation, Structure, and Properties of a Novel Rectorite/Nitrile Butadiene Rubber (NBR) Nanocomposites

Rectorite/nitrile butadiene rubber (NBR) nanocomposite was firstly prepared by co-coagulating NBR latex and rectorite water suspension. The microstructure of the resulted nanocomposite was characterized by transmission electron microscopy (TEM) and X-ray diffraction (XRD). The results indicated that the rectorite layers were dispersed in the NBR matrix in form of single layers...

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

Background MiR-221 and miR-222 (miR-221/222) are frequently up-regulated in various types of human malignancy including glioblastoma. Recent studies have reported that miR-221/222 regulate cell growth and cell cycle progression by targeting p27 and p57. However the underlying mechanism involved in cell survival modulation of miR-221/222 remains elusive. Results Here we showed...