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Search: authors:"Xu Zhang"

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Fibulin-1 is epigenetically down-regulated and related with bladder cancer recurrence

Background Bladder cancer is one of the most common cancers worldwide. Fibulin-1, a multi-functional extracellular matrix protein, has been demonstrated to be involved in many kinds of cancers, while its function in bladder cancer remains unclear. So here we investigated the expression and function of fibulin-1 in Bladder cancer. Methods We used real-time PCR, Western blot...

Presence of intratumoral platelets is associated with tumor vessel structure and metastasis

Background Platelets play a fundamental role in maintaining hemostasis and have been shown to participate in hematogenous dissemination of tumor cells. Abundant platelets were detected in the tumor microenvironment outside of the blood vessel, thus, platelet -tumor cell interaction outside of the bloodstream may play a role in regulating primary tumor growth and metastasis...