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The Relationship between Frequently Used Glucose-Lowering Agents and Gut Microbiota in Type 2 Diabetes Mellitus

Metabolic diseases, especially diabetes mellitus, have become global health issues. The etiology of diabetes mellitus can be attributed to genetic and/or environmental factors. Current evidence suggests the association of gut microbiota with metabolic diseases. However, the effects of glucose-lowering agents on gut microbiota are poorly understood. Several studies revealed that...

Advances in T-cell checkpoint immunotherapy for head and neck squamous cell carcinoma

Advances in T-cell checkpoint immunotherapy for head and neck squamous cell carcinoma Xinmeng Qi,1,2,* Bo Jia,3,* Xue Zhao,1 Dan Yu1 1Department of Otolaryngology Head and Neck Surgery, The Second

Involvement of proapoptotic genes in autophagic cell death induced by irradiation

, Eastern Hepatobiliary Surgery Hospital, The Second Military Medical University, Shanghai 200438, ChinaJianrui Song, Xue Zhao & Lixin WeiDepartment of Cell and Developmental Biology, University of Michigan ... ScholarSearch for Xue Zhao in:Nature Research journals • PubMed • Google ScholarSearch for Yi Feng in:Nature Research journals • PubMed • Google ScholarSearch for Sheng Xu in:Nature Research journals • PubMed

A cross-sectional study of inpatients with late stage of dementia in Southeast China and the associations between biochemical parameters and apolipoprotein E genotypes

,3,* Mei-Fang Chen,3 Zheng Wang,3 Ming-Xue Zhao,3 Bin-Hua Chen,3 Hong-Lei Li1 1Department of Neurology and Research Center of Neurology, The Second Affiliated Hospital of Zhejiang University School of

Factors Affecting Energy-Related Carbon Emissions in Beijing-Tianjin-Hebei Region

Beijing-Tianjin-Hebei is a typical developed region in China. The development of economy has brought lots of carbon emissions. To explore an effective way to reduce carbon emissions, we applied the Logarithmic Mean Divisia Index (LMDI) model to find drivers behind carbon emission from 2003 to 2013. Results showed that, in Beijing, Tianjin, and Hebei, economic output was main...

Factors Affecting Energy-Related Carbon Emissions in Beijing-Tianjin-Hebei Region

Beijing-Tianjin-Hebei is a typical developed region in China. The development of economy has brought lots of carbon emissions. To explore an effective way to reduce carbon emissions, we applied the Logarithmic Mean Divisia Index (LMDI) model to find drivers behind carbon emission from 2003 to 2013. Results showed that, in Beijing, Tianjin, and Hebei, economic output was main...

Efficient string similarity join in multi-core and distributed systems

In big data area a significant challenge about string similarity join is to find all similar pairs more efficiently. In this paper, we propose a parallel processing framework for efficient string similarity join. First, the input is split into some disjoint small subsets according to the joint frequency distribution and the interval distribution of strings. Then the filter...

Hepatitis B virus X protein is capable of down-regulating protein level of host antiviral protein APOBEC3G

. Zhao for the kind gift of Ub-HA expression plasmid. Author information Author notesRuidong Chen & Xue Zhao These authors contributed equally to this work. AffiliationsKey Laboratory of Medical ... Molecular Virology (MOE/MOH) and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, People’s Republic of ChinaRuidong Chen, Xue Zhao, Yongxiang Wang, Youhua Xie

Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network

,1,3 Zhi-fang Xu,1,3 Xue Zhao,1,3 Jiang Wang,2 Yi Guo,1,4 Kai Li,5 and Sha-sha Ding6 1Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin ... , Xue Zhao, and Kai Li reviewed and edited the manuscript. All authors read and approved the manuscript. Kuo Zhang and Xin-meng Guo contributed equally to this work. Acknowledgments This work was

Applying Statistical and Complex Network Methods to Explore the Key Signaling Molecules of Acupuncture Regulating Neuroendocrine-Immune Network

,1,3 Zhi-fang Xu,1,3 Xue Zhao,1,3 Jiang Wang,2 Yi Guo,1,4 Kai Li,5 and Sha-sha Ding6 1Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin ... , Xue Zhao, and Kai Li reviewed and edited the manuscript. All authors read and approved the manuscript. Kuo Zhang and Xin-meng Guo contributed equally to this work. Acknowledgments This work was

Inhibition of autophagy increased AGE/ROS-mediated apoptosis in mesangial cells

The aim of our study was to investigate the role of autophagy, a homeostatic process involved in the lysosomal degradation of damaged cell organelles and proteins, in regulating the survival of mesangial cells treated with advanced glycation end products (AGEs). In the present study, AGEs induced mitochondrial depolarization and led to mitochondrial-dependent apoptosis in...

Decreased Cardiovascular Risk after Roux-en-Y Gastric Bypass Surgery in Chinese Diabetic Patients with Obesity

4 July 2017 Academic Editor: Alfredo Vannacci Copyright © 2017 Xue Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted ... . Conflicts of Interest The authors declare that they have no competing interests. Authors’ Contributions Xue Zhao and Wenyan Duan designed this study. Xianchao Xiao, Zhuo Li, and Gang Wang recruited the

The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review

, China Received 10 April 2016; Revised 16 July 2016; Accepted 1 August 2016 Academic Editor: Konstantinos Kantartzis Copyright © 2016 Xue Zhao et al. This is an open access article distributed under ... ”, “insulin resistance”, “nuclear magnetic spectroscopy,” “NMR”, and “mass spectrometry”. Two persons (Xue Zhao and Qing Han) independently did the search process in order to minimize selection bias. If there

The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review

, China Received 10 April 2016; Revised 16 July 2016; Accepted 1 August 2016 Academic Editor: Konstantinos Kantartzis Copyright © 2016 Xue Zhao et al. This is an open access article distributed under ... ”, “insulin resistance”, “nuclear magnetic spectroscopy,” “NMR”, and “mass spectrometry”. Two persons (Xue Zhao and Qing Han) independently did the search process in order to minimize selection bias. If there

Using Metabolomic Profiles as Biomarkers for Insulin Resistance in Childhood Obesity: A Systematic Review

March 2016; Revised 28 May 2016; Accepted 15 June 2016 Academic Editor: Stefania Camastra Copyright © 2016 Xue Zhao et al. This is an open access article distributed under the Creative Commons ... ”, “metabolites”, “nuclear magnetic spectroscopy,” and “mass spectrometry”. In this procedure, two investigators (Xue Zhao and Qing Han) independently completed this work in order to minimize selection bias. If

Efficacy differences of electroacupuncture with single acupoint or matching acupoints for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial

Previous studies have shown that acupuncture is beneficial for the alleviation of chemotherapy-induced nausea and vomiting. However, there is a lack of clinical evidence concerning the effects of acupoint-matching on chemotherapy-induced nausea and vomiting. This is a parallel randomized controlled trial to evaluate the occurrence of nausea and vomiting after chemotherapy (the...

Antihypertensive and Antihypertrophic Effects of Acupuncture at PC6 Acupoints in Spontaneously Hypertensive Rats and the Underlying Mechanisms

, Yu-Xue Zhao, Xiang-Hong Jing, and Xiao-Chun Yu Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei, Beijing 100700, China Correspondence ... Wang, and Feng-Yan Lu. Yu-Xue Zhao and Xiang-Hong Jing provided advice on the statistical analyses and data interpretation. Juan-Juan Xin, Xiao-Chun Yu, and Jun-Hong Gao drafted and finalized the paper

Antihypertensive and Antihypertrophic Effects of Acupuncture at PC6 Acupoints in Spontaneously Hypertensive Rats and the Underlying Mechanisms

, Yuan- Yuan Wang, and Feng-Yan Lu. Yu-Xue Zhao and Xiang-Hong Jing provided advice on the statistical analyses and data interpretation. Juan-Juan Xin, Xiao-Chun Yu, and Jun-Hong Gao drafted and finalized

Antihypertensive and Antihypertrophic Effects of Acupuncture at PC6 Acupoints in Spontaneously Hypertensive Rats and the Underlying Mechanisms

, Yu-Xue Zhao, Xiang-Hong Jing, and Xiao-Chun Yu Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei, Beijing 100700, China Correspondence ... Wang, and Feng-Yan Lu. Yu-Xue Zhao and Xiang-Hong Jing provided advice on the statistical analyses and data interpretation. Juan-Juan Xin, Xiao-Chun Yu, and Jun-Hong Gao drafted and finalized the paper