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515 papers found.
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Development of number-space associations: SNARC effects and spatial attention in 7- to 11-year-olds

Associations; NO, 31860281) Author Contributions Funding acquisition: Yun Pan. Methodology: Yun Pan. Project administration: Yun Pan. Supervision: Yun Pan, Xuejun Bai, Yan Chen. Validation: Yun Pan, Xuejun ... Bai. Writing ? original draft: Yun Pan, Xiaohong Han. Writing ? review & editing: Yun Pan, Xiaohong Han, Gaoxing Mei, Yan Chen. 15 / 19 16 / 19 17 / 19 18 / 19 1. de Hevia M. D. , Girelli L

Electrically conductive highly elastic polyamide/lycra fabric treated with PEDOT:PSS and polyurethane

Conductive elastic fabrics are desirable in wearable electronics and related applications. Highly elastic conductive polyamide/lycra knitted fabric was prepared using intrinsically conductive polymer poly (3,4-ethylenedioxythiophene) (PEDOT) blended with polyelectrolyte poly (styrene sulfonate) (PSS) using easily scalable coating and immersion methods. The effects of these two...

The distinct role of CD73 in the progression of pancreatic cancer

Recent studies have shown that the non-enzymatic function of CD73 plays a key role in tumor progression, but this function of CD73 in pancreatic cancer cells has not been studied. Furthermore, little is known about the mechanism involved in CD73 regulation in tumors. Here, we found that CD73 expression was upregulated in pancreatic ductal adenocarcinoma (PDAC) and that its...

Effects of Exchange Benefits, Security Concerns and Situational Privacy Concerns on Mobile Commerce Adoption

Privacy Concerns on Mobile Commerce Adoption Hua Dai Information Systems Department University of Wisconsin-La Crosse USA Yan Chen Information Systems Department Auburn University at Montgomery, USA

Review of Development Status of Bi2Te3-Based Semiconductor Thermoelectric Power Generation

Semiconductor thermoelectric power generation is a new type of energy-saving and environment-friendly power generation technology, which directly converts heat energy into electrical energy by using the characteristics of semiconductor thermoelectric materials and has broad application prospects. This paper introduces the basic principles of thermoelectric materials and...

Temperature-Dependent HfO2/Si Interface Structural Evolution and its Mechanism

In this work, hafnium oxide (HfO2) thin films are deposited on p-type Si substrates by remote plasma atomic layer deposition on p-type Si at 250 °C, followed by a rapid thermal annealing in nitrogen. Effect of post-annealing temperature on the crystallization of HfO2 films and HfO2/Si interfaces is investigated. The crystallization of the HfO2 films and HfO2/Si interface is...

A rapid methods development workflow for high-throughput quantitative proteomic applications

researchers for providing C. glutamicum, A. tumefaciens, and R. toruloides cells for analysis. Author Contributions Conceptualization: Yan Chen, Christopher J. Petzold. Data curation: Yan Chen. Formal ... analysis: Yan Chen, Christopher J. Petzold. Funding acquisition: Jay D. Keasling, Paul D. Adams. Investigation: Yan Chen, Jonathan Vu, Mitchell G. Thompson, William A. Sharpless, Leanne Jade G. Chan

Rab27b Is a Potential Indicator for Lymph Node Metastasis and Unfavorable Prognosis in Lung Adenocarcinoma

Rab27b is reported to associate with the development and progression of several types of human cancers. However, the relationship between Rab27b expression and the clinical characteristics of lung adenocarcinoma (LUAD) is rarely explored. In this present study, the TCGA database was consulted, followed by one-step quantitative reverse transcription polymerase chain reaction (qPCR...

A self-feedback strategy differential evolution with fitness landscape analysis

Differential evolution (DE) has been widely applied to complex global optimization problems. Different search strategies have been designed to find the optimum conditions in a fitness landscape. However, none of these strategies works well over all possible fitness landscapes. Since the fitness landscape associated with a complex global optimization problem usually consists of...

Joint Probability-Based Neuronal Spike Train Classification

1748-670X Joint probability-based neuronal spike train classification Yan Chen 0 Vitaliy Marchenko 0 Robert F. Rogers 0 0 Department of Electrical and Computer Engineering, University of Delaware

New Strategies for Alzheimer Disease and Cognitive Impairment

Approximately five million people suffer with Alzheimer disease (AD) and more than twenty-four million people are diagnosed with AD, pre-senile dementia, and other disorders of cognitive loss worldwide. Furthermore, the annual cost per patient with AD can approach $200,000 with an annual population aggregate cost of $100 billion. Yet, complete therapeutic prevention or reversal...

A Fork in the Path: Developing Therapeutic Inroads with FoxO Proteins

Advances in clinical care for disorders involving any system of the body necessitates novel therapeutic strategies that can focus upon the modulation of cellular proliferation, metabolism, inflammation and longevity. In this respect, members of the mammalian forkhead transcription factors of the O class (FoxOs) that include FoxO1, FoxO3, FoxO4 and FoxO6 are increasingly being...

Wnt1 Neuroprotection Translates into Improved Neurological Function during Oxidant Stress and Cerebral Ischemia Through AKT1 and Mitochondrial Apoptotic Pathways

Although essential for the development of the nervous system, Wnt1 also has been associated with neurodegenerative disease and cognitive loss during periods of oxidative stress. Here we show that endogenous expression of Wnt1 is suppressed during oxidative stress in both in vitro and in vivo experimental models. Loss of endogenous Wnt1 signaling directly correlates with neuronal...

Mammalian Target of Rapamycin: Hitting the Bull's-Eye for Neurological Disorders

The mammalian target of rapamycin (mTOR) and its associated cell signaling pathways have garnered significant attention for their roles in cell biology and oncology. Interestingly,the explosion of information in this field has linked mTOR to neurological diseases with promising initial studies. mTOR, a 289 kDa serine/threonine protein kinase, plays an important role in cell...

Twist of Tubular Mechanical Metamaterials Based on Waterbomb Origami

Origami-inspired mechanical metamaterials have recently drawn increasing attention since their flexible mechanical performance has been greatly enhanced by introducing origami patterns to the thin-shell structures. As a typical origami pattern, the waterbomb tube could be adopted to the design of mechanical metamaterials. However, existing designs predominantly make use of the...

Erythropoietin, Forkhead Proteins, and Oxidative Injury: Biomarkers and Biology

Oxidative stress significantly impacts multiple cellular pathways that can lead to the initiation and progression of varied disorders throughout the body. It therefore becomes imperative to elucidate the components and function of novel therapeutic strategies against oxidative stress to further clinical diagnosis and care. In particular, both the growth factor and cytokine...

New Strategies for Alzheimer Disease and Cognitive Impairment

Approximately five million people suffer with Alzheimer disease (AD) and more than twenty-four million people are diagnosed with AD, pre-senile dementia, and other disorders of cognitive loss worldwide. Furthermore, the annual cost per patient with AD can approach $200,000 with an annual population aggregate cost of $100 billion. Yet, complete therapeutic prevention or reversal...

Wnt1 Neuroprotection Translates into Improved Neurological Function during Oxidant Stress and Cerebral Ischemia Through AKT1 and Mitochondrial Apoptotic Pathways

Although essential for the development of the nervous system, Wnt1 also has been associated with neurodegenerative disease and cognitive loss during periods of oxidative stress. Here we show that endogenous expression of Wnt1 is suppressed during oxidative stress in both in vitro and in vivo experimental models. Loss of endogenous Wnt1 signaling directly correlates with neuronal...

Therapeutic Promise and Principles: Metabotropic Glutamate Receptors

For a number of disease entities, oxidative stress becomes a significant factor in the etiology and progression of cell dysfunction and injury. Therapeutic strategies that can identify novel signal transduction pathways to ameliorate the toxic effects of oxidative stress may lead to new avenues of treatment for a spectrum of disorders that include diabetes, Alzheimer's disease...

A Fork in the Path: Developing Therapeutic Inroads with FoxO Proteins

Advances in clinical care for disorders involving any system of the body necessitates novel therapeutic strategies that can focus upon the modulation of cellular proliferation, metabolism, inflammation and longevity. In this respect, members of the mammalian forkhead transcription factors of the O class (FoxOs) that include FoxO1, FoxO3, FoxO4 and FoxO6 are increasingly being...