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26 papers found.
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A Driving Violation Index Modelling Study at Intersections in Urban Precincts Using Big Data

Driving violations at intersections are profoundly prevalent in urban precinct in China. These violations, including failing to stop for a red traffic light or arrow, driving across single continuous dividing line, disobeying traffic lane markings, and illegal parking, have become a major issue not only impacting the overall safety of the cities, but also causing traffic delays...

A Driving Violation Index Modelling Study at Intersections in Urban Precincts Using Big Data

Driving violations at intersections are profoundly prevalent in urban precinct in China. These violations, including failing to stop for a red traffic light or arrow, driving across single continuous dividing line, disobeying traffic lane markings, and illegal parking, have become a major issue not only impacting the overall safety of the cities, but also causing traffic delays...

Phosphorylation of STAT3 at Tyr705 regulates MMP-9 production in epithelial ovarian cancer

Contributions Conceptualization: Zan-Hui Jia. Data curation: Feng-Jun Guo, Jun Chen. Formal analysis: Yan Jia, Feng-Jun Guo, Man-Hua Cui. Methodology: Jun Chen, Xi-Wen Zhang. Resources: Zan-Hui Jia

Limited role of sessile acidophiles in pyrite oxidation below redox potential of 650 mV

Pyrite oxidation by mixed mesophilic acidophiles was conducted under conditions of controlled and non-controlled redox potential to investigate the role of sessile microbes in pyrite oxidation. Microbes attached on pyrite surfaces by extracellular polymeric substances (EPS), and their high coverage rate was characterized by scanning electron microscopy (SEM), confocal laser...

Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers

Increasing evidence suggests that the interaction of human islet amyloid polypeptide (hIAPP) with lipids may facilitate hIAPP aggregation and cause the death of pancreatic islet β-cells. However, the detailed hIAPP-membrane interactions and the influences of lipid compositions are unclear. In this study, as a first step to understand the mechanism of membrane-mediated hIAPP...

Analysis of the disturbance voltage and gpr in substation and mobile base station co-construction

It is essential to consider the electrical safety protection distance when the mobile base station and the substation are building together. This paper makes an analysis from three aspects: the influence on the disturbance voltage of the secondary cable in substation when the station is struck by lightning; the influence on the base station grounding grid caused by the station...

Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations

, Cornell University, Ithaca, New York 14853, USAXiaolai Zhou, Lirong Sun, Ji Whae Choi, Yan Jia, Owen Adam Brady & Fenghua HuDepartment of Neurobiology, School of Basic Medical Sciences, Southern Medical ... in:Nature Research journals • PubMed • Google ScholarSearch for Ji Whae Choi in:Nature Research journals • PubMed • Google ScholarSearch for Yan Jia in:Nature Research journals • PubMed • Google ScholarSearch

Image quality and radiation dose of dual-source CT cardiac angiography using prospective ECG-triggering technique in pediatric patients with congenital heart disease

: Signal to noise ratio; CTDIvol: Volume CT dose index; DLP: Dose length product. Competing interests One of the authors Yan Jia is Siemens employee. Authors’ contributions YL and MWZ carried out the

cAMP/PKA Pathways and S56 Phosphorylation Are Involved in AA/PGE2-Induced Increases in rNaV1.4 Current

Arachidonic acid (AA) and its metabolites are important second messengers for ion channel modulation. The effects of extracellular application of AA and its non-metabolized analogue on muscle rNaV1.4 Na+ current has been studied, but little is known about the effects of intracellular application of AA on this channel isoform. Here, we report that intracellular application of AA...

Engineering a Carbohydrate-processing Transglycosidase into Glycosyltransferase for Natural Product Glycodiversification

• PubMed • Google ScholarSearch for Yi Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Yan Jia in:Nature Research journals • PubMed • Google ScholarSearch for Wenzhao Wang in:Nature

The AlpArray Seismic Network: A Large-Scale European Experiment to Image the Alpine Orogen

The AlpArray programme is a multinational, European consortium to advance our understanding of orogenesis and its relationship to mantle dynamics, plate reorganizations, surface processes and seismic hazard in the Alps–Apennines–Carpathians–Dinarides orogenic system. The AlpArray Seismic Network has been deployed with contributions from 36 institutions from 11 countries to map...

Stability Analysis of the Supercritical Surface Quasi-Geostrophic Equation

June 2013; Accepted 21 August 2013 Academic Editor: Diego Córdoba Copyright © 2013 Yan Jia et al. This is an open access article distributed under the Creative Commons Attribution License, which

The Alteration and Clinical Significance of Th22/Th17/Th1 Cells in Patients with Chronic Myeloid Leukemia

T helper- (Th-) cell immunodeficiency plays important roles in tumor development and their effects in chronic myeloid leukemia (CML) remain unclear. In the present study, we mainly investigated the role of Th22, Th17, and Th1 cell and their related cytokines (IL-22, IL-17, and IFN-r) in the pathophysiology of CML. Bone marrow (BM) and peripheral blood (PB) were extracted from...

Identifying Vulnerable Nodes of Complex Networks in Cascading Failures Induced by Node-Based Attacks

In the research on network security, distinguishing the vulnerable components of networks is very important for protecting infrastructures systems. Here, we probe how to identify the vulnerable nodes of complex networks in cascading failures, which was ignored before. Concerned with random attack (RA) and highest load attack (HL) on nodes, we model cascading dynamics of complex...

Effect of ASF (a Compound of Traditional Chinese Medicine) on Behavioral Sensitization Induced by Ethanol and Conditioned Place Preference in Mice

,1,2 Ling-yan Jia,1,2 and Sen Zhong1,2 1Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, China 2Department of Infectious Diseases, Affiliated

Hypermethylation of Sp1 Binding Site Suppresses Hypothalamic POMC in Neonates and May Contribute to Metabolic Disorders in Adults: Impact of Maternal Dietary CLAs

Epigenetic regulation of neuropeptide genes associated with central appetite control plays an important part in the development of nutritional programming. While proopiomelanocortin (POMC) is critical in appetite control, the molecular mechanism of methylation-related regulation of POMC remains unclear. Based on the report that the proximal specificity protein 1 (Sp1) binding...

Anomalous Gray Matter Structural Networks in Patients with Hepatitis B Virus-Related Cirrhosis without Overt Hepatic Encephalopathy

Background and Purpose Increasing evidence suggests that cirrhosis may affect the connectivity among different brain regions in patients before overt hepatic encephalopathy (OHE) occurs. However, there has been no study investigating the structural reorganization of these altered connections at the network level. The primary focus of this study was to investigate the abnormal...