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In silico identification of genetic mutations conferring resistance to acetohydroxyacid synthase inhibitors: A case study of Kochia scoparia

editor for their critical comments that enriched the discussion section. Author Contributions Data curation: Yan Li, Ping Gong. Formal analysis: Yan Li. Methodology: Yan Li. Project administration ... : Ping Gong. Resources: Ping Gong. Software: Yan Li. Writing ? original draft: Yan Li. Funding acquisition: Michael D. Netherland, Ping Gong. Conceptualization: Michael D. Netherland, Chaoyang Zhang

The Trimming-Based Design Method for PWR Coolant Flow Distribution Device

In order to resolve the situations of nonuniform coolant flow distribution and insufficient vortex suppression, the existing Pressurized Water Reactor (PWR) usually adopts complex coolant mixing structures. However, those structures will greatly increase the complexity and maintenance cost of the system. To solve this problem, a trimming-based design method is proposed in this...

Intranasal immunization with recombinant outer membrane protein A induces protective immune response against Stenotrophomonas maltophilia infection

: Yan Li. Investigation: Yan Li, Xueping Tang. Methodology: Xueyi Shang, Zhihua Kou. Project administration: Yan Li. Resources: Yongqiang Jiang. Software: Zunquan Zhao, Hui Wang, Xin Wang ... . Supervision: Xueyi Shang, Peng Liu, Yongqiang Jiang. Validation: Yan Li, Xueping Tang. Visualization: Yan Li, Xueping Tang. Writing ? original draft: Yan Li. Writing ? review & editing: Yan Li. 10 / 12

Predicting population age structures of China, India, and Vietnam by 2030 based on compositional data

. Forecast-Vietnam-2. (PNG) S225 Fig. Forecast-Vietnam-3. (PNG) Conceptualization: Yigang Wei, Yan Li. Formal analysis: Huiwen Wang. Funding acquisition: Huiwen Wang. Investigation: Yigang Wei. Methodology ... : Zhichao Wang. Software: Zhichao Wang, Huiwen Wang. Supervision: Yigang Wei, Yan Li. Validation: Yigang Wei. Writing ? original draft: Yan Li, Zhenyu Jiang. 1. Luo L. Predicted Mathematical Model and

Two new species and a new combination of Allacta (Blattodea, Ectobiidae, Pseudophyllodromiinae) from China, with notes on their behavior in nature

-Li Che 0 Zong-Qing Wang 0 0 Institute of Entomology, College of Plant Protection, Southwest University , Beibei, Chongqing, 400716 , China Two new species, Allacta bruna sp. n. and Allacta alba sp. n

A Common Variant of ASAP1 Is Associated with Tuberculosis Susceptibility in the Han Chinese Population

Background. ASAP1 (also known as AMAP1 or DDEF1) encodes an Arf GTPase-activating protein (Arf GAP), a multifunctional scaffold protein that induces hydrolysis of GTP bound to the ADP-ribosylation factor (Arf) family GTP-binding proteins. Reduction of ASAP1 expression in vitro was related to suppression of cell migration and invasiveness. The genetic variant rs4733781 of the...

Stability Analysis and Control Optimization of a Prey-Predator Model with Linear Feedback Control

The application of pest management involves two thresholds when the chemical control and biological control are adopted, respectively. Our purpose is to provide an appropriate balance between the chemical control and biological control. Therefore, a Smith predator-prey system for integrated pest management is established in this paper. In this model, the intensity of...

Evaluation of GBLUP, BayesB and elastic net for genomic prediction in Chinese Simmental beef cattle

) correlations and standard errors (SE) between all pairs of ten traits. Author Contributions Conceptualization: Lingyang Xu, Junya Li. Data curation: Xiaoqiao Wang, Jian Miao, Yan Li. Formal analysis: Jian ... Chang, Jiangwei Xia. Software: Binxin An. Supervision: Binxin An, Lupei Zhang, Xue Gao, Huijiang Gao. Validation: Tianpeng Chang, Yan Li. Visualization: Yan Li, Lupei Zhang, Xue Gao. Writing

Edge-grafting theorems on permanents of Laplacian matrices of graphs and their applications

- SHUCHAO LI†, YAN LI† , AND XIXI ZHANG† AMS subject classifications. 05C50, 05C05. 1. Introduction. Let G = (VG, EG) be a simple connected graph with vertex set VG = {v1, . . . , vn} and edge set EG 6

Retrieval of Semantic-Based Inspirational Sources for Emotional Design

, Chengdu, China Correspondence should be addressed to Yan Li; nc.ude.ucs@nayil Received 14 March 2018; Revised 24 September 2018; Accepted 17 October 2018; Published 8 November 2018 Academic Editor

Network Pharmacology-Based Study on the Mechanism of Bushen-Jianpi Decoction in Liver Cancer Treatment

published article and supplementary materials. Disclosure Rong Wu, Xiao-Yan Li, and Wen-Hai Wang contributed equally (co-first authors) to this work. Conflicts of Interest The authors declare that they have ... no conflicts of interest. Authors’ Contributions Shi-Bing Su, Rong Wu, and Xiao-Yan Li contributed to the conception of the work, the acquisition, and analysis of the data and drafting of the paper

Generation of Bose-Einstein Condensates’ Ground State Through Machine Learning

We show that both single-component and two-component Bose-Einstein condensates’ (BECs) ground states can be simulated by a deep convolutional neural network. We trained the neural network via inputting the parameters in the dimensionless Gross-Pitaevskii equation (GPE) and outputting the ground-state wave function. After the training, the neural network generates ground-state...

ESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer

ESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer Xiong-Bo Guo,1,* Bin Huang,1,* Ying-Hua Pan,2 Shu-Guang Su,3 Yan Li3 1Department of General Surgery, Institute of Surgery Research, Daping Hospital, Army Medical University, Chongqing, China; 2Department of Rheumatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou...

Small-Molecule Targets in Tumor Immunotherapy

Cancer immunotherapy has been widely recognized as a powerful approach to fight cancers. To date, over 50 phase III trials in cancer immunotherapy are in progress. Among the many immunotherapy approaches, immune checkpoint therapy has attracted considerable attention. The reported clinical success of targeting the T cell immune checkpoint receptors PD-1 or CTLA4 by antibodies...

Thermal Errors Classification Compensation without Sensor for CNC Machine Tools

Both multicollinearity and utilization deficiency of temperature sensors affect the robustness and the prediction precision of traditional thermal error prediction models. To address the problem, a thermal error prediction model without temperature sensors is proposed. Firstly, the paper analyzes the temperature field and thermal deformation mechanisms of the spindle of a CNC...

Modeling and Distribution Laws of Drilling Force for Staggered Teeth BTA Deep Hole Drill

The boring and trepanning association (BTA) deep hole drilling is a typical self-guiding machining method. The drilling force and its distribution laws along the cutting radius directly affect the stability of drilling and the quality of machined hole. Based on the oblique cutting theory, a novel drilling force model is developed to predict the thrust and torque for staggered...

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo Jie Wang,1 Huaxin Liang,2 Meiyan Sun,3 Lei Zhang,3 Huijing Xu,3 Wei Liu,3 Yan Li,3 Yue Zhou,4 Yingya Li,5