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Mechanistic insight into the interaction of gastrointestinal mucus with oral diblock copolymers synthesized via ATRP method

Mechanistic insight into the interaction of gastrointestinal mucus with oral diblock copolymers synthesized via ATRP method Jiao Liu,1,* Jie Cao,1,* Jianhua Cao,2 Shangcong Han,1 Yan Liang,1 Mingfeng ... ( O r I g I N a l r e s e a r c h Jianhua cao 2 shangcong han 1 Yan liang 1 Yong sun 1 Introduction: Nanoparticles are increasingly used as drug carriers for oral administration. The delivery of drug

Revisiting radiative decays of \(1^{+-}\) heavy quarkonia in the covariant light-front approach

We revisit the calculation of the width for the radiative decay of a \(1^{+-}\) heavy \(Q \bar{Q}\) meson via the channel \(1^{+-} \rightarrow 0^{-+} +\gamma \) in the covariant light-front quark model. We carry out the reduction of the light-front amplitude in the non-relativistic limit, explicitly computing the leading and next-to-leading order relativistic corrections. This...

Transcriptome analyses suggest a novel hypothesis for whitefly adaptation to tobacco

, Institute of Insect Sciences, Zhejiang University, Hangzhou, 310058, ChinaWen-Qiang Xia, Xin-Ru Wang, Yan Liang, Shu-Sheng Liu & Xiao-Wei Wang AuthorsSearch for Wen-Qiang Xia in:Nature Research journals ... • PubMed • Google Scholar Search for Xin-Ru Wang in:Nature Research journals • PubMed • Google Scholar Search for Yan Liang in:Nature Research journals • PubMed • Google Scholar Search for Shu-Sheng Liu

Combination of twelve alleles at six quantitative trait loci determines grain weight in rice

, Zhijuan Ji, Zhihua Wen, Yan Liang. Funding acquisition: Changdeng Yang. Investigation: Yuxiang Zeng, Zhijuan Ji, Zhihua Wen, Yan Liang. Project administration: Changdeng Yang. Resources: Junsheng Shi

Hemostatic chemical constituents from natural medicine Toddalia asiatica root bark by LC-ESI Q-TOF MSE

Background Toddalia asiatica root bark as an effective hemostatic natural medicine or Chinese materia medica was applied in China for long history, its complex drug action mechanisms and unclear substance basis have been constraining the development of this drug. Results An intelligentized strategy by LC-ESI Q-TOF MSE was presented in this study for rapid identification of...

Up-regulation of lncRNA CASC9 promotes esophageal squamous cell carcinoma growth by negatively regulating PDCD4 expression through EZH2

Abnormal expression of numerous long non-coding RNAs (lncRNAs) has been reported in esophageal squamous cell carcinoma (ESCC) recently, but the great majority of their roles and mechanisms remain largely unclear. We aim to identify the critical ESCC-associated lncRNAs and elucidate the functions and mechanisms in detail. Microarrays were used to analyze the differentially...

Plasma fibrin D-dimer and the risk of left atrial thrombus: A systematic review and meta-analysis

Background Plasma fibrin d-dimer has been taken as a marker for thrombus. The aim of this study was to evaluate the relationship between d-dimer (DD) levels and left atrial spontaneous echo contrast (SEC)/left atrial thrombus (LAT). Methods We identified clinical studies by systematic search of MEDLINE and EMBASE databases up to Feb 2016. All observational studies that considered...

Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer

Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer Yan Liang,1 Baocheng Tian,1 Jing

DEPTOR-mTOR Signaling Is Critical for Lipid Metabolism and Inflammation Homeostasis of Lymphocytes in Human PBMC Culture

Abnormal immune response of the body against substances and tissues causes autoimmune diseases, such as polymyositis, dermatomyositis, and rheumatoid arthritis. Irregular lipid metabolism and inflammation may be a significant cause of autoimmune diseases. Although much progress has been made, mechanisms of initiation and proceeding of metabolic and inflammatory regulation in...

SlMAPK3 enhances tolerance to tomato yellow leaf curl virus (TYLCV) by regulating salicylic acid and jasmonic acid signaling in tomato (Solanum lycopersicum)

Several recent studies have reported on the role of mitogen-activated protein kinase (MAPK3) in plant immune responses. However, little is known about how MAPK3 functions in tomato (Solanum lycopersicum L.) infected with tomato yellow leaf curl virus (TYLCV). There is also uncertainty about the connection between plant MAPK3 and the salicylic acid (SA) and jasmonic acid (JA...

Transcriptomic profiling in muscle and adipose tissue identifies genes related to growth and lipid deposition

(, for editing the English Yiren Gu, Xuebin Lv. Gu, Xuebin Lv. Conceptualization: Xuan Tao, Yan Liang, Yiren Gu, Xuebin Lv. Formal analysis: Xuan Tao, Yan Liang, Xuemei Yang, Yiren Gu, Xuebin ... Lv. Funding acquisition: Yiren Gu, Xuebin Lv. Investigation: Xuan Tao, Yan Liang, Xuemei Yang, Jianhui Pang, Zhijun Zhong, Xiaohui Chen, Yuekui Yang, Kai Zeng, Runming Kang, Yunfeng Lei, Sancheng

Autocrine activity of BDNF induced by the STAT3 signaling pathway causes prolonged TrkB activation and promotes human non-small-cell lung cancer proliferation

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin superfamily, which has been implicated in the pathophysiology of the nervous system. Recently, several studies have suggested that BDNF and/or its receptor, tropomyosin related kinase B (TrkB), are involved in tumor growth and metastasis in several cancers, including prostate cancer, neuroblastoma...

Deviating from the nanorod shape: Shape-dependent plasmonic properties of silver nanorice and nanocarrot structures

Noble metallic nanostructures exhibit special optical properties resulting from excitation of surface plasmons. Among the various metallic nanostructures, nanorods have attracted particular attention because of their unique and intriguing shape-dependent plasmonic properties. Nanorods can support transverse and longitudinal plasmon modes, the latter ones depending strongly on the...

Response to: ‘Body mass index and the risk of rheumatoid arthritis: a systematic review and dose–response meta-analysis’ - authors’ reply

Liang 0 Zaixing Yang 0 Renqian Zhong 0 0 Department of Laboratory Diagnostics, Changzheng Hospital, Second Military Medical University , 415 Fengyang Road, Shanghai , China © 2015 Qin et al. Open Access

The Combined Effects of Arbuscular Mycorrhizal Fungi (AMF) and Lead (Pb) Stress on Pb Accumulation, Plant Growth Parameters, Photosynthesis, and Antioxidant Enzymes in Robinia pseudoacacia L.

Arbuscular mycorrhizal fungi (AMF) are considered as a potential biotechnological tool for improving phytostabilization efficiency and plant tolerance to heavy metal-contaminated soils. However, the mechanisms through which AMF help to alleviate metal toxicity in plants are still poorly understood. A greenhouse experiment was conducted to evaluate the effects of two AMF species...

The roles of arbuscular mycorrhizal fungi (AMF) in phytoremediation and tree-herb interactions in Pb contaminated soil

the China Scholarship Council (201306300018). Author information Author notesYurong Yang & Yan Liang These authors contributed equally to this work. AffiliationsState Key Laboratory of Soil Erosion ... for Yan Liang in:Nature Research journals • PubMed • Google ScholarSearch for Xiaozhen Han in:Nature Research journals • PubMed • Google ScholarSearch for Tsan-Yu Chiu in:Nature Research journals

Phenol Removal by a Novel Non-Photo-Dependent Semiconductor Catalyst in a Pilot-Scaled Study: Effects of Initial Phenol Concentration, Light, and Catalyst Loading

A novel non-photo-dependent semiconductor catalyst (CT) was employed to degrade phenol in the present pilot-scaled study. Effect of operational parameters such as phenol initial concentration, light area, and catalyst loading on phenol degradation, was compared between CT catalyst and the conventional photocatalyst titanium dioxide. CT catalyst excelled titanium dioxide in...

Tight regulation of plant immune responses by combining promoter and suicide exon elements

Effector-triggered immunity (ETI) is activated when plant disease resistance (R) proteins recognize the presence of pathogen effector proteins delivered into host cells. The ETI response generally encompasses a defensive ‘hypersensitive response’ (HR) that involves programmed cell death at the site of pathogen recognition. While many R protein and effector protein pairs are known...