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TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway

Mesenchymal stromal cells (MSCs) were originally characterized by the ability to differentiate into different mesenchymal lineages in vitro, and their immunomodulatory and trophic functions have recently aroused significant interest in the application of MSCs in cell-based regenerative medicine. However, a major problem in clinical practice is the replicative senescence of MSCs...

The effects of genetic variation and environmental factors on rhynchophylline and isorhynchophylline in Uncaria macrophylla Wall. from different populations in China

: Xiao-Jun Ma. Investigation: Yan-Hong Guan, Hai-Tao Li, Shu-Gen Wei, Li-Xia Zhang. Methodology: Mei-Fang Song, Zhong-Lian Zhang. Project administration: Zhong-Lian Zhang, Xiao-Jun Ma. Resources: Mei ... -Fang Song, Yan-Hong Guan, Hai-Tao Li, Zhong-Lian Zhang. Supervision: Zhong-Lian Zhang, Xiao-Jun Ma. Writing ? original draft: Mei-Fang Song. Writing ? review & editing: Mei-Fang Song, Zhong-Lian Zhang