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6 papers found.
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FSD-C10, a Fasudil derivative, promotes neuroregeneration through indirect and direct mechanisms

. Experiments were analyzed by Student?s t-tests, and P-values were considered statistically significant when P < 0.05. 1 5 Author Contributions Yan-hua Li and Cong Xie, Yuan Zhang and Xing Li participated in

Fasudil regulates T cell responses through polarization of BV-2 cells in mice experimental autoimmune encephalomyelitis

microglia/macrophages and the balance of immune cells during the progression of EAE. Author contribution Chan CHEN, Yan-hua LI, Qiong ZHANG, and Yong-fei ZHAO performed research; Jie-zhong YU and Bao-guo ... Chan Chen in:Nature Research journals • PubMed • Google ScholarSearch for Yan-hua Li in:Nature Research journals • PubMed • Google ScholarSearch for Qiong Zhang in:Nature Research journals • PubMed

Observation of Pain-Sensitive Points along the Meridians in Patients with Gastric Ulcer or Gastritis

This study aims to investigate the sensitization of human skin points along certain meridians related to visceral disease by using the pressure-pain threshold (PPT) as an indicator. We detected and compared the PPTs of people with and without gastric ulcer or gastritis on the related acupoints, abdomen area, and back area with von Frey detector and observed the similarities and...

A mitochondrial mutation A4401G is involved in the pathogenesis of left ventricular hypertrophy in Chinese hypertensives

The left ventricular hypertrophy (LVH) is one of the most important organ damage targets in hypertension. Despite the involvement of multiple factors, the genetic factors have been shown to have an important function in the pathogenesis of LVH. The aim of our study was to evaluate the role of mitochondria in LVH for Chinese hypertensives. A systematic and extended mutational...

The role of mitochondrial genome in essential hypertension in a Chinese Han population

Earlier genetic studies of essential hypertension have focused on nuclear genes or family-based mitochondrial screening in Caucasian and African-American pedigrees. The role of mitochondria in sporadic Chinese hypertensives is unknown. We sequenced mitochondrial genomes in 306 age- and gender-balanced Chinese Han hypertensives and controls. In 153 hypertensives, putative...

Trends in incidence and mortality of nasopharyngeal carcinoma over a 20–25 year period (1978/1983–2002) in Sihui and Cangwu counties in southern China

Background Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world but is common in southern China. A recent report from the Hong Kong Cancer Registry, a high-risk area for NPC in southern China, showed that incidence rate decreased by 29% for males and by 30% for females from 1980–1999, while mortality rate decreased by 43% for males and 50% for females...