Advanced search    

Search: authors:"Yang Li"

12 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

CHD1L contributes to cisplatin resistance by upregulating the ABCB1–NF-κB axis in human non-small-cell lung cancer

request. Author information Author notes These authors contributed equally: Yang Li, Li-Ru He, Ying Gao, Ning-Ning Zhou AffiliationsAffiliated Cancer Hospital & Institute of Guangzhou Medical University ... , Guangzhou, ChinaXin-Ke Zhou & Ji-Fang Liu AuthorsSearch for Yang Li in:Nature Research journals • PubMed • Google Scholar Search for Li-Ru He in:Nature Research journals • PubMed • Google Scholar Search for

Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy

University, Harbin, ChinaFan Yang, Jie Lv, Yueqiu Wang, Hui Che, Yang Li & Lihong WangTranslational Medicine Research and Cooperation Center of Northern China, Heilongjiang Academy of Medical Sciences, Harbin ... journals • PubMed • Google Scholar Search for Er Yue in:Nature Research journals • PubMed • Google Scholar Search for Long Ren in:Nature Research journals • PubMed • Google Scholar Search for Yang Li

Humanized mice reveal an essential role for human hepatocytes in the development of the liver immune system

The liver is an immunological organ with a distinct immune cell profile. Although the composition and function of liver immune cells have been widely investigated, the mechanisms regulating the development and homeostasis of the specialized immune system, especially in humans, remain largely unknown. Herein, we address this question in humanized mice (hu-mice) that were...

Functional screen analysis reveals miR-3142 as central regulator in chemoresistance and proliferation through activation of the PTEN-AKT pathway in CML

, Bing Liu, Yang Li & Li Jia AuthorsSearch for Lifen Zhao in:Nature Research journals • PubMed • Google ScholarSearch for Yujia Shan in:Nature Research journals • PubMed • Google ScholarSearch for Bing Liu ... in:Nature Research journals • PubMed • Google ScholarSearch for Yang Li in:Nature Research journals • PubMed • Google ScholarSearch for Li Jia in:Nature Research journals • PubMed • Google Scholar Competing

miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1

Impairment in gut barrier function induced by intestinal ischemia/reperfusion (I/R) injury is associated with high morbidity and mortality. Intestinal barrier function requires the tight coordination of epithelial migration, proliferation and differentiation. We previously observed that nuclear receptor-related protein 1 (nurr1)-mediated proliferative pathway was impaired in...

Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer

Metastasis is a multistep molecular network process, which is the major cause of death in patients with colorectal cancer (CRC). MicroRNAs (miRNAs) play pivotal roles in tumorigenesis as either tumor suppressors or oncogenes. Increased expression of fucosyltransferase4 (FUT4) has been reported to be associated with the invasive and metastatic properties of CRC. Here to identify...

Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway

Jianping Zhou He Song Yang Li Jian Zhang Shuangning Ding Our previous study showed that Calreticulin (CRT) promoted the development of pancreatic cancer (PC) through ERK/MAPK pathway. We next investigate

Neuroglobin boosts axon regeneration during ischemic reperfusion via p38 binding and activation depending on oxygen signal

Cerebral ischemia causes severe cell death or injury including axon breakdown or retraction in the brain. Axon regeneration is crucial for the functional recovery of injured neurons or brains after ischemia/reperfusion (I/R); however, this process has been proved extremely difficult in adult brains and there is still no effective therapy for it. Here we reported that neuroglobin...

PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth

The p21-activated kinase 4 (PAK4) is overexpressed in different cancers and promotes proliferation of cancer cells. Reprogramming of glucose metabolism is found in most cancer cells which in turn supports rapid proliferation. However, the relationship between PAK4 and glucose metabolism in cancer cells has not been explored. In this study, we reported that PAK4 promoted glucose...

MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer

Accumulating evidences have revealed that dysregulated microRNAs (miRNAs) involve in the tumorigenesis, progression and even lead to poor prognosis of various carcinomas, including breast cancer. MiRNA-106b-5p (miR-106b) and miRNA-93-5p (miR-93) levels were confirmed to be significantly upregulated in breast cancer clinical samples (n=36) and metastatic cell line (MDA-MB-231...

Histone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition

Dorfman Yang Li Zhenguo Zhao Yida Pan Qian Zhou Shan Huang Shimin Zhao Yuling Yao Xiaoping Zou Histone deacetylase 3 (HDAC3) has an oncogenic role in apoptosis and contributes to the proliferation of

MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-κB signaling pathway

Huang Ta Xiao Jiao-Yang Li Yuan-Yuan Wang Juan Feng Jin-Feng Zhu Shan-Shan Lu Hong Yi Zhi-Qiang Xiao MiR-125b is aberrantly expressed and has a role in the various types of tumors. However, the role and