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23 papers found.
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Structure-activity relationship optimization for lassa virus fusion inhibitors targeting the transmembrane domain of GP2

CAS (NBL2017008), the Open Research Fund Program of the State Key Laboratory of Virology of China (2018IOV001). Guangshun Zhang, Junyuan Cao, Yan Cai, Yang Liu, Yanli Li, Peilin Wang, Jiao Guo

miR-98-5p contributes to cisplatin resistance in epithelial ovarian cancer by suppressing miR-152 biogenesis via targeting Dicer1

Epithelial ovarian cancer (EOC) is a highly lethal gynecological malignancy, and cisplatin resistance is usually correlated with the poor prognosis of EOC. Increasing evidence indicates that the dysregulation of miRNAs is related to chemotherapy sensitivity. In this study, we revealed that miR-98-5p, a member of the let-7 family, was enriched in cisplatin-resistant EOC cells...

An equity analysis of health examination service utilization by women from underdeveloped areas in western China

. Investigation: Yuyan Qian, Zhongliang Zhou, Ju'e Yan, Yongjian Xu, Xiaowei Yang, Yanli Li. Resources: Jianmin Gao, Zhongliang Zhou. Writing ± original draft: Yuyan Qian. Writing ± review & editing: Yuyan Qian

An economy-related equity analysis of health service utilization by women in economically underdeveloped regions of western China

The Chinese government has long been committed to eliminating the inequality in the utilization of health services; however, it still lacks an analysis or measurement of the economy-related inequality in the utilization of women’s health services. The economy-related utilization of health services in women aged 15 years and above was assessed by the horizontal inequity index of a...

Modeling of hydrogen atom diffusion and response behavior of hydrogen sensors in Pd–Y alloy nanofilm

Liu finished the theoretical modeling and wrote the main manuscript text and prepared all the figures. Yanli Li and Pengcheng Huang finish the experiments. Han Song and Gang Zhang analyzed experimental

Risk of chemotherapy-induced febrile neutropenia with early discontinuation of pegfilgrastim prophylaxis in US clinical practice

Barron, Yanli Li, Maureen Reiner, Spiros Tzivelekis, and Jacob Garcia are employed by, and are stockholders in, Amgen Inc. Open Access This article is distributed under the terms of the Creative Commons

Associations between FAS rs2234767 and FASL rs763110 polymorphisms and the risk of lung cancer: a meta-analysis of 39,736 subjects

Associations between FAS rs2234767 and FASL rs763110 polymorphisms and the risk of lung cancer: a meta-analysis of 39,736 subjects Xiongjie Yu,1,* Yanli Li,2,* Yuandong Yu,1 Jinhua Lei,1 Guoxing Wan

Predicting Soil Salinity with Vis–NIR Spectra after Removing the Effects of Soil Moisture Using External Parameter Orthogonalization

Robust models for predicting soil salinity that use visible and near-infrared (vis–NIR) reflectance spectroscopy are needed to better quantify soil salinity in agricultural fields. Currently available models are not sufficiently robust for variable soil moisture contents. Thus, we used external parameter orthogonalization (EPO), which effectively projects spectra onto the...

Decomposing socioeconomic inequalities in depressive symptoms among the elderly in China

Background Accelerated population ageing brings about unprecedented challenges to the health system in China. This study aimed to measure the prevalence and the income-related inequality of depressive symptoms, and also identify the determinants of depressive symptom inequality among the elderly in China. Methods Data were drawn from the second wave of the China Health and...

Trajectory of absolute neutrophil counts in patients treated with pegfilgrastim on the day of chemotherapy versus the day after chemotherapy

standards Conflict of interest Yanli Li, Zandra Klippel, Maureen Reiner, and John H. Page are employees of and own stock in Amgen Inc. Xiaolong Shih and Hong Wang are consultants to Amgen and are funded by

Distinct functional enrichment of transcriptional signatures in pigs with high and low IFN-gamma responses after vaccination with a porcine reproductive and respiratory syndrome virus (PRRSV)

Little is known about the host factor in the response to PRRSV vaccination. For this purpose, piglets were immunized with a commercial PRRSV-live vaccine and classified as high responders (HR) or low responders (LR) as regards to the frequencies of virus-specific IFN-γ-secreting cells. Six weeks post vaccination, PBMCs isolated from three individuals with the most extreme...

Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection

Severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-like coronavirus are a potential threat to global health. However, reviews of the long-term effects of clinical treatments in SARS patients are lacking. Here a total of 25 recovered SARS patients were recruited 12 years after infection. Clinical questionnaire responses and examination findings indicated that the...

Exploring the nonlinear relationship between body mass index and health-related quality of life among adults: a cross-sectional study in Shaanxi Province, China

Introduction China is a country facing the “double burden” of both obesity and underweight. The objective of this study was to explore the relationship between body mass index (BMI) and health-related quality of life (HRQOL) in adults from Shaanxi Province. Methods The data were derived from the fifth Health Service Survey of Shaanxi Province, which was part of China’s National...

A hierarchical graph model for object cosegmentation

Yanli Li 0 Zhong Zhou 0 Wei Wu 0 0 State Key Laboratory of Virtual Reality Technology & Systems, Beihang University , Beijing, China Given a set of images containing similar objects, cosegmentation

Measurement and explanation of socioeconomic inequality in catastrophic health care expenditure: evidence from the rural areas of Shaanxi Province

Province, the outpatient visits ratios within two weeks rose from 11.18 % in 2008 to 12.55 % in 2013, and the annual hospitalisation rate jumped from 5.39 % in 2008 to 10.06 % in 2013 (Yongjian Xu, Yanli Li

Positive Relationship between Total Antioxidant Status and Chemokines Observed in Adults

Copyright © 2014 Yanli Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

A metabolomics study delineating geographical location-associated primary metabolic changes in the leaves of growing tobacco plants by GC-MS and CE-MS

Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, ChinaYanni Zhao, Jieyu Zhao, Chunxia Zhao, Yanli Li, Junjie Zhang, Lili Li, Chunxiu Hu ... • PubMed • Google ScholarSearch for Huina Zhou in:Nature Research journals • PubMed • Google ScholarSearch for Yanli Li in:Nature Research journals • PubMed • Google ScholarSearch for Junjie Zhang in:Nature

Analysis of the supply-demand status of China’s natural gas to 2020

The reserves, distribution, production and utilization of natural gas resources in China are introduced in this paper which leads a point of view that China’s natural gas resources are relatively rich while distributed unevenly. The future production and consumption of China’s natural gas are predicted using the Generalized Weng model and the Gray prediction model. The prediction...