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Certain new bounds considering the weighted Simpson-like type inequality and applications

We investigate a weighted Simpson-type identity and obtain new estimation-type results related to the weighted Simpson-like type inequality for the first-order differentiable mappings. We also present some applications to f-divergence measures and to higher moments of continuous random variables.

Inhibition of ROS-mediated activation Src-MAPK/AKT signaling by orientin alleviates H2O2-induced apoptosis in PC12 cells

Inhibition of ROS-mediated activation Src-MAPK/AKT signaling by orientin alleviates H2O2-induced apoptosis in PC12 cells Shimei Qi,1,2,* Zunyong Feng,1,3,* Qiang Li,1,2 Zhilin Qi,1,2 Yao Zhang1,2 1Anhui Province Key Laboratory of Active Biological Macro-molecules, Wannan Medical College, Wuhu 241002, People’s Republic of China; 2Department of Biochemistry, Wannan Medical College...

Different types of quantum integral inequalities via ( α , m ) $(\alpha ,m)$ -convexity

In this paper, based on ( α , m ) $(\alpha,m)$ -convexity, we establish different type inequalities via quantum integrals. These inequalities generalize some results given in the literature.

Phase 1 Parkinson’s Disease Studies Show the Dopamine D1/D5 Agonist PF-06649751 is Safe and Well Tolerated

version for submission. Disclosures David L. Gray is an employee of the study sponsor, Pfizer. Sridhar Duvvuri is an employee of the study sponsor, Pfizer. Yao Zhang is an employee of the study sponsor

Large increase in global storm runoff extremes driven by climate and anthropogenic changes

Weather extremes have widespread harmful impacts on ecosystems and human communities with more deaths and economic losses from flash floods than any other severe weather-related hazards. Flash floods attributed to storm runoff extremes are projected to become more frequent and damaging globally due to a warming climate and anthropogenic changes, but previous studies have not...

Molecular characterization of a 31 kDa protein from Trichinella spiralis and its induced immune protection in BALB/c mice

Trichinella spiralis is an important foodborne zoonotic parasite and it is necessary to develop a vaccine in order to interrupt transmission from animals to humans. A 31 kDa protein from T. spiralis (Ts31) is an antigen targeted by protective antibodies, and Ts31 contains a domain of trypsin-like serine protease that might have the function of serine protease. The purpose of this...

Chronic fatigue syndrome patients have alterations in their oral microbiome composition and function

Zhang, Hongyan Xiong. Investigation: Lei Yu, Keli Pan, Minglu Mo, Mingxiang Duan, Yao Zhang, Hongyan Xiong. Methodology: Taiwu Wang, Cong Xu, Hongyan Xiong. Resources: Keli Pan, Hongyan Xiong. Software ... : Taiwu Wang. Supervision: Yao Zhang, Hongyan Xiong. Validation: Cong Xu. Visualization: Taiwu Wang, Lei Yu. Writing ? original draft: Taiwu Wang, Lei Yu, Mingxiang Duan, Yao Zhang, Hongyan Xiong

CTEN induces epithelial-mesenchymal transition (EMT) and metastasis in non small cell lung cancer cells

) Author Contributions Data curation: Xiangdong Lu, Tao Zhao. Formal analysis: Juan Gao. Funding acquisition: Tingrong Zhang. Methodology: Juan Gao, Yao Zhang. Project administration: Tingrong Zhang

Tolerance induced by Porphyromonas gingivalis may occur independently of TLR2 and TLR4

. Writing ± original draft: Wei Lu, Jian-yu Gu. Writing ± review & editing: Ying Sun. Investigation: Wei Lu, Jian-yu Gu, Yao-yao Zhang, Dan-Jun Gong, Yi-ming Zhu. 11 / 14 12 / 14 13 / 14 1. Ji S , Choi YS

Unplanned reoperation after radical gastrectomy for gastric cancer: causes, risk factors, and long-term prognostic influence

Unplanned reoperation after radical gastrectomy for gastric cancer: causes, risk factors, and long-term prognostic influence Xueliang Zuo,1,* Juan Cai,2,* Zhiqiang Chen,3,* Yao Zhang,3 Jian Wu,1

Facilitators and barriers for HIV-testing in Zambia: A systematic review of multi-level factors

. Author Contributions Conceptualization: Xiaoming Li, J. Anitha Menon. Formal analysis: Shan Qiao, Yao Zhang. Funding acquisition: Shan Qiao. Methodology: Shan Qiao, Yao Zhang, Xiaoming Li. Project ... administration: Shan Qiao, Xiaoming Li. Resources: Shan Qiao, Yao Zhang. Supervision: Xiaoming Li, J. Anitha Menon. Validation: Shan Qiao. Visualization: Shan Qiao, Yao Zhang. Writing ± original draft: Shan

Characterization of a serine protease inhibitor from Trichinella spiralis and its participation in larval invasion of host’s intestinal epithelial cells

Trichinella spiralis serine protease inhibitor (TsSPI) was identified in ES proteins of adult worms (AW), the TsSPI gene was highly expressed at enteral stage worms (AW and newborn larvae), distributed mainly in the cuticle and stichosome of this nematode. Vaccination of mice with rTsSPI exhibited a 62.2% reduction of intestinal AW and a 57.25% reduction of muscle larvae after...

Genome sequence of Acuticoccus yangtzensis JL1095T (DSM 28604T) isolated from the Yangtze Estuary

Yao Zhang 0 1 0 Institute of Marine Microbes and Ecospheres, Xiamen University , Xiamen 361102 , People's Republic of China 1 State Key Laboratory of Marine Environmental Sciences, Xiamen University

Active cell-matrix coupling regulates cellular force landscapes of cohesive epithelial monolayers

Epithelial cells can assemble into cohesive monolayers with rich morphologies on substrates due to competition between elastic, edge, and interfacial effects. Here we present a molecularly based thermodynamic model, integrating monolayer and substrate elasticity, and force-mediated focal adhesion formation, to elucidate the active biochemical regulation over the cellular force...

CYP1A1 Relieves Lipopolysaccharide-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells

-Qing Gao; nc.ude.ufawn@gniqgnimoag Received 30 July 2017; Revised 29 November 2017; Accepted 11 December 2017; Published 28 February 2018 Academic Editor: Anshu Agrawal Copyright © 2018 Wen-Yao Zhang ... Interest The authors declare that they have no competing financial interests. Authors’ Contributions Wen-Yao Zhang, Yong Zhang, and Ming-Qing Gao participated in the design of the study. Hao Wang, Shaopei Qi

CYP1A1 Relieves Lipopolysaccharide-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells

-Qing Gao; nc.ude.ufawn@gniqgnimoag Received 30 July 2017; Revised 29 November 2017; Accepted 11 December 2017; Published 28 February 2018 Academic Editor: Anshu Agrawal Copyright © 2018 Wen-Yao Zhang ... Interest The authors declare that they have no competing financial interests. Authors’ Contributions Wen-Yao Zhang, Yong Zhang, and Ming-Qing Gao participated in the design of the study. Hao Wang, Shaopei Qi

A global moderate resolution dataset of gross primary production of vegetation for 2000–2016

Accurate estimation of the gross primary production (GPP) of terrestrial vegetation is vital for understanding the global carbon cycle and predicting future climate change. Multiple GPP products are currently available based on different methods, but their performances vary substantially when validated against GPP estimates from eddy covariance data. This paper provides a new GPP...

Salidroside Inhibits HMGB1 Acetylation and Release through Upregulation of SirT1 during Inflammation

HMGB1, a highly conserved nonhistone DNA-binding protein, plays an important role in inflammatory diseases. Once released to the extracellular space, HMGB1 acts as a proinflammatory cytokine that triggers inflammatory reaction. Our previous study showed that salidroside exerts anti-inflammatory effect via inhibiting the JAK2-STAT3 signalling pathway. However, whether salidroside...

HIV epidemics in Shenzhen and Chongqing, China

Yang, Ziqian Zeng, Yafei Li, Yao Zhang, Zhengrong Yang. Formal analysis: Shu Yang, Alice P. Y. Chiu, Qianying Lin, Ziqian Zeng, Lin Yang, Daihai He. 12 / 15 Funding acquisition: Shu Yang, Yafei Li, Yao ... Yang, Daihai He. Project administration: Shu Yang, Daihai He. Resources: Zhengrong Yang. Software: Qianying Lin. Supervision: Yao Zhang, Daihai He. Validation: Ziqian Zeng. Visualization: Lin Yang

Myricitrin Modulates NADPH Oxidase-Dependent ROS Production to Inhibit Endotoxin-Mediated Inflammation by Blocking the JAK/STAT1 and NOX2/p47phox Pathways

, China 3Department of Forensic Medicine, Wannan Medical College, Wuhu, China Correspondence should be addressed to Yao Zhang; nc.vog.udeha@oaygnahz Received 10 October 2016; Revised 24 December 2016