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Search: authors:"Yaojie Shi"

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Benzothiazinethione is a potent preclinical candidate for the treatment of drug-resistant tuberculosis

New chemotherapeutic compounds are needed to combat multidrug-resistant Mycobacterium tuberculosis (Mtb), which remains a serious public-health challenge. Decaprenylphosphoryl-β-D-ribose 2′-epimerase (DprE1 enzyme) has been characterized as an attractive therapeutic target to address this urgent demand. Herein, we have identified a new class of DprE1 inhibitors...

Corrigendum: Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

, Qiang Feng, XinyuYou, TinghongYe, Qian Lei 1 Yongxia Zhu , Menghua Xiong,Yong Xia, FangfangYang,Yaojie Shi,Yuquan Wei, Lidan Zhang & In the Results section under subheading 'Impact of ZLD1039 on breast