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56 papers found.
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Adverse stroke outcomes among patients with bipolar disorder

-Chang Shia, Herng-Ching Lin, Jiunn-Horng Kang. Methodology: Pao-Huan Chen, Yi-Wei Kao, Ben-Chang Shia, Herng-Ching Lin. Writing ? original draft: Pao-Huan Chen, Yi-Wei Kao, Ben-Chang Shia, Herng-Ching

The comparison of non-vitamin K antagonist oral anticoagulants versus well-managed warfarin with a lower INR target of 1.5 to 2.5 in Asians patients with non-valvular atrial fibrillation

, Kuang-Tso Lee, Samuel Chi-Ling Hang. Methodology: Yi-Hsin Chan, Yi-Wei Kao, Chien-Ying Huang, Yung-Lung Chen. 14 / 16 Software: Yung-Lung Chen. Supervision: Pao-Hsien Chu. Validation: Samuel Chi-Ling

Identifying genetic diversity of O antigens in Aeromonas hydrophila for molecular serotype detection

the strains. We thank Dr. Laiyou Wang for helpful suggestions. Author Contributions Funding acquisition: Bin Yang, Bin Liu. Data curation: Hengchun Cao, Chengqian Qian, Zhiqiu Yin, Lu Wang, Yi Wei

Distinct mucosal microbial communities in infants with surgical necrotizing enterocolitis correlate with age and antibiotic exposure

NEC/non-NEC status had a much stronger effect on microbial richness than infant age. (TIF) Author Contributions Conceptualization: Joann Romano-Keeler, Yi-Wei Tang, Jo?rn-Hendrik Weitkamp. Data ... Tovchigrechko, Chunlin Wang, Robert M. Brucker, Daniel J. Moore, Christopher Fonnesbeck, Hernan Correa, Yi-Wei Tang, Lora Hooper, Seth R. Bordenstein, Suman R. Das, Jo?rn-Hendrik Weitkamp. Project

Arecoline inhibits the growth of 3T3-L1 preadipocytes via AMP-activated protein kinase and reactive oxygen species pathways

at the Academia Sinica, Taiwan, for technical assistance. Conceptualization: Jueng-Tsueng Weng, Yi-Wei Tsuei, Tsu-Shing Wang, Yung-Hsi Kao. Formal analysis: Zi-Han Tian, Li-Jane Shih, An-Ci Siao, Tsai ... -Yun Chan. Funding acquisition: Yi-Wei Tsuei, Yow-Chii Kuo, Yung-Hsi Kao. Investigation: Zi-Han Tian, An-Ci Siao, Tsai-Yun Chan, Yung-Hsi Kao. Methodology: Zi-Han Tian. Project administration: Zi-Han

In-depth study of DNA binding of Cys2His2 finger domains in testis zinc-finger protein

Previously, we identified that both fingers 1 and 2 in the three Cys2His2 zinc-finger domains (TZD) of testis zinc-finger protein specifically bind to its cognate DNA; however, finger 3 is non-sequence–specific. To gain insights into the interaction mechanism, here we further investigated the DNA-binding characteristics of TZD bound to non-specific DNAs and its finger segments...

The herbal decoction modified Danggui Buxue Tang attenuates immune-mediated bone marrow failure by regulating the differentiation of T lymphocytes in an immune-induced aplastic anemia mouse model

Conceptualization: Limin Chai. Data curation: Peiying Deng, Xue Li, Yi Wei. Formal analysis: Peiying Deng, Xue Li, Yi Wei, Juan Liu, Meng Chen. Funding acquisition: Limin Chai. Investigation: Lingqun Zhu, Limin

Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4

a grant from Academia Sinica and Ministry of Science and Technology, Taiwan (105-0210-0113-01). Data curation: Chinpan Chen, You-Di Liao. Formal analysis: Ting-Wei Chang, Shu-Yi Wei, Shih-Han Wang ... , Hung-Mu Wei, Yu-June Wang, Chiu-Feng Wang. Funding acquisition: Chinpan Chen, You-Di Liao. Investigation: Ting-Wei Chang, Shu-Yi Wei, Shih-Han Wang, Hung-Mu Wei, Yu-June Wang, Chiu-Feng Wang

Preliminary dosimetric study on feasibility of multi-beam boron neutron capture therapy in patients with diffuse intrinsic pontine glioma without craniotomy

Diffuse intrinsic pontine glioma is a very frustrating disease. Since the tumor infiltrates the brain stem, surgical removal is often impossible. For conventional radiotherapy, the dose constraint of the brain stem impedes attempts at further dose escalation. Boron neutron capture therapy (BNCT), a targeted radiotherapy, carries the potential to selectively irradiate tumors with...

An Early Instance of Upper Palaeolithic Personal Ornamentation from China: The Freshwater Shell Bead from Shuidonggou 2

We report the discovery and present a detailed analysis of a freshwater bivalve from Shuidonggou Locality 2, layer CL3. This layer is located c. 40 cm below layer CL2, which has yielded numerous ostrich eggshell beads. The shell is identified as the valve of a Corbicula fluminea. Data on the occurrence of this species in the Shuidonggou region during Marine Isotope Stage 3 and...

Nasal nitric oxide in unilateral sinus disease

Unilateral sinus disease (USD) can sometimes be difficult to accurately diagnose before surgery. The application of nasal nitric oxide (nNO) for USD diagnosis and its surgical outcome in USD has not been reported in the literature. We prospectively enrolled sixty-six USD patients who underwent endoscopic sinus surgery for fungal rhinosinusitis (n = 19), chronic rhinosinusitis...

Inactivation of SmeSyRy Two-Component Regulatory System Inversely Regulates the Expression of SmeYZ and SmeDEF Efflux Pumps in Stenotrophomonas maltophilia

SmeYZ efflux pump is a critical pump responsible for aminoglycosides resistance, virulence-related characteristics (oxidative stress susceptibility, motility, and secreted protease activity), and virulence in Stenotrophomonas maltophilia. However, the regulatory circuit involved in SmeYZ expression is little known. A two-component regulatory system (TCS), smeRySy, transcribed...

The Description of Shale Reservoir Pore Structure Based on Method of Moments Estimation

Shale has been considered as good gas reservoir due to its abundant interior nanoscale pores. Thus, the study of the pore structure of shale is of great significance for the evaluation and development of shale oil and gas. To date, the most widely used approaches for studying the shale pore structure include image analysis, radiation and fluid invasion methods. The detailed pore...

The SLC6A3 gene possibly affects susceptibility to late-onset alcohol dependence but not specific personality traits in a Han Chinese population

Dopaminergic dysfunction has an important role in the pathoetiology of alcohol dependence (AD). The purpose of this study was to determine whether the solute carrier family 6 member 3 (SLC6A3) gene (also known as the dopamine transporter DAT gene) was associated with AD, and whether variants in the SLC6A3 locus were associated with specific personality traits in patients with AD...

Morphogenetic Studies of the Drosophila DA1 Ventral Olfactory Projection Neuron

In the Drosophila olfactory system, odorant information is sensed by olfactory sensory neurons and relayed from the primary olfactory center, the antennal lobe (AL), to higher olfactory centers via olfactory projection neurons (PNs). A major portion of the AL is constituted with dendrites of four groups of PNs, anterodorsal PNs (adPNs), lateral PNs (lPNs), lateroventral PNs...

SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer

Aims Lung cancer is one of the most deadly cancers; median survival from diagnosis is less than one year in those with advanced disease. Novel lung cancer biomarkers are desperately needed. In this study, we evaluated SULF2 expression by immunohistochemistry and its association with overall survival in a cohort of patients with non-small cell lung cancer (NSCLC). We also looked...

Impact of chronic rhinosinusitis on severe asthma patients

Coexistence of chronic rhinosinusitis (CRS) with asthma appears to impair asthma control. Type-2 innate lymphoid cells (ILC2s) respond to the cytokines of thymic stromal lymphopoietin (TSLP), interleukin (IL)-25 and IL-33, thus contributing to airway diseases such as CRS and asthma. We investigate whether the augmented Th2-cytokines in CRS might be related to sinonasal tract...

Expression and Functions of CreD, an Inner Membrane Protein in Stenotrophomonas maltophilia

CreBC is a highly conserved two-component regulatory system (TCS) in several gram-negative bacteria, including Escherichia coli, Aeromonas spp., Pseudomonas aeruginosa, and Stenotrophomonas maltophilia. CreD is a conserved gene that encodes a predicted inner-membrane protein and is located near the creBC loci. Activation of CreBC increases creD expression; therefore, creD...

Correlation between the Uptake of 18F-Fluorodeoxyglucose (18F-FDG) and the Expression of Proliferation-Associated Antigen Ki-67 in Cancer Patients: A Meta-Analysis

Objective To study the correlation between 18F-FDG uptake and cell proliferation in cancer patients by meta-analysis of published articles. Methods We searched PubMed (MEDLINE included), EMBASE, and Cochrane Database of Systematic Review, and selected research articles on the relationship between 18F-FDG uptake and Ki-67 expression (published between August 1, 1994-August 1, 2014...

Comparison of Long-Term Outcomes of Postmastectomy Radiotherapy between Breast Cancer Patients with and without Immediate Flap Reconstruction

Purpose To compare the long-term clinical outcomes of postmastectomy radiotherapy (PMRT) between breast cancer patients with and without immediate transverse rectus abdominis myocutaneous (TRAM) flap reconstruction. Methods The study included 492 patients with stage II or III breast cancer who underwent modified radical mastectomy (MRM) and chemotherapy followed by PMRT between...