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Search: authors:"Yi-Jun Liu"

3 papers found.
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Cathepsin D deficiency delays central nervous system myelination by inhibiting proteolipid protein trafficking from late endosome/lysosome to plasma membrane

Guo Lin Xiao Yi-Jun Liu Chen Shen Hui-Fang Lou Yan Lv Shu-Yi Pan This study aimed to investigate the role of cathepsin D (CathD) in central nervous system (CNS) myelination and its possible mechanism

Estimating long-term clinical effectiveness and cost-effectiveness of HPV 16/18 vaccine in China

Background Human papillomavirus (HPV) 16 and 18 are the two most common HPV oncogenic types that can be prevented by vaccination. This study aimed at assessing the cost-effectiveness of 3 doses of the bivalent HPV vaccine in rural and urban settings in China. Methods A Markov model was adapted to reflect the lifetime of a modelled 100,000 12-year-old girls cohort in rural and...

Effect of vaccination age on cost-effectiveness of human papillomavirus vaccination against cervical cancer in China

Background The cost-effectiveness of human papillomavirus (HPV) vaccination in women pre-sexual debut has been demonstrated in many countries. This study aimed to estimate the cost-effectiveness of a 3-dose bivalent HPV vaccination at ages 12 to 55 year in both rural and urban settings in China. Methods The Markov cohort model simulated the natural history of HPV infection and...