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Chlorella diet alters mitochondrial cardiolipin contents differentially in organs of Danio rerio analyzed by a lipidomics approach

(SAS-MOST JRP 2016/4) to MB. We would like to thank Hsin-Yu Hou for the maintenance of the zebrafish stock. Author Contributions Conceptualization: Yi-Wen Liu, Yuan-Hao Howard Hsu. Data curation: Yu ... -Jen Chao, Maria Balazova, Ting-Yuan Wu, Jamie Lin, Yi-Wen Liu, Yuan Hao Howard Hsu. Formal analysis: Wen-Hsin Wu, Maria Balazova, Yuan-Hao Howard Hsu. Funding acquisition: Maria Balazova, Yi-Wen Liu

The interaction of arsenic and N-butyl-N-(4-hydroxybutyl)nitrosamine on urothelial carcinogenesis in mice

-Hsein Chen, Yi-Wen Liu. Data curation: Mohammad Mezbahul Haque, Wei-Han Lin, Yi-Wen Liu. Formal analysis: Yuan-Chang Dai, Yi-Wen Liu. Funding acquisition: Shou-Chieh Wang. Investigation: Yuan-Chang ... Dai, Shou-Chieh Wang, Yi-Wen Liu. Methodology: Yuan-Chang Dai, Lei-Chen Lin. Supervision: Ching-Hsein Chen, Yi-Wen Liu. Writing ± original draft: Yi-Wen Liu. Writing ± review & editing: Yuan-Chang

Gene Expression and DNA Methylation Status of Glutathione S-Transferase Mu1 and Mu5 in Urothelial Carcinoma

Bladder cancer is highly recurrent after therapy, which has an enormous impact on the health and financial condition of the patient. It is worth developing diagnostic tools for bladder cancer. In our previous study, we found that the bladder carcinogen BBN increased urothelial global DNA CpG methylation and decreased GSTM1 protein expression in mice. Here, the correlation of BBN...

The Hemodynamically-Regulated Vascular Microenvironment Promotes Migration of the Steroidogenic Tissue during Its Interaction with Chromaffin Cells in the Zebrafish Embryo

Background While the endothelium-organ interaction is critical for regulating cellular behaviors during development and disease, the role of blood flow in these processes is only partially understood. The dorsal aorta performs paracrine functions for the timely migration and differentiation of the sympatho-adrenal system. However, it is unclear how the adrenal cortex and medulla...

Development and Fibronectin Signaling Requirements of the Zebrafish Interrenal Vessel

Background The early morphogenetic steps of zebrafish interrenal tissue, the teleostean counterpart of the mammalian adrenal gland, are modulated by the peri-interrenal angioblasts and blood vessels. While an organized distribution of intra-adrenal vessels and extracellular matrix is essential for the fetal adrenal cortex remodeling, whether and how an intra-interrenal buildup of...

Cortex Moutan Induces Bladder Cancer Cell Death via Apoptosis and Retards Tumor Growth in Mouse Bladders

Cortex Moutan is the root bark of Paeonia suffruticosa Andr. It is the herbal medicine widely used in Traditional Chinese Medicine for the treatment of blood-heat and blood-stasis syndrome. Furthermore, it has been reported that Cortex Moutan has anticancer effect. In this study, the Cortex Moutan extract was evaluated in bladder cancer therapy in vitro and in vivo. Cortex Moutan...

Cortex Moutan Induces Bladder Cancer Cell Death via Apoptosis and Retards Tumor Growth in Mouse Bladders

Cortex Moutan is the root bark of Paeonia suffruticosa Andr. It is the herbal medicine widely used in Traditional Chinese Medicine for the treatment of blood-heat and blood-stasis syndrome. Furthermore, it has been reported that Cortex Moutan has anticancer effect. In this study, the Cortex Moutan extract was evaluated in bladder cancer therapy in vitro and in vivo. Cortex Moutan...

Clinical and experimental studies regarding the expression and diagnostic value of carcinoembryonic antigen-related cell adhesion molecule 1 in non-small-cell lung cancer

Background Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a multifunctional Ig-like cell adhesion molecule that has a wide range of biological functions. According to previous reports, serum CEACAM1 is dysregulated in different malignant tumours and associated with tumour progression. However, the serum CEACAM1 expression in non-small-cell lung carcinomas...

Audio Watermarking through Deterministic plus Stochastic Signal Decomposition

rate, 16-bit PCM) from Yi-Wen Liu?s own collection of CDs. Brief description of the music can be found in Table 1. The F-QIM step size is 12 cents above 500 Hz, the same for all files. The attempted

Anti-Bladder-Tumor Effect of Baicalein from Scutellaria baicalensis Georgi and Its Application In Vivo

Some phytochemicals with the characteristics of cytotoxicity and/or antimetastasis have generated intense interest among the anticancer studies. In this study, a natural flavonoid baicalein was evaluated in bladder cancer in vitro and in vivo. Baicalein inhibits 5637 cell proliferation. It arrests cells in G1 phase at 100 μM and in S phase below 75 μM. The protein expression of...

4′-Chloro-3,5-dihydroxystilbene, a resveratrol derivative, induces lung cancer cell death

-jing CHUANG 3 Yi-wen LIU 0 0 Graduate Institute of Biomedical and Biopharmaceutical Sciences 1 Department of Internal Medicine, Buddhist Tzuchi Dalin General Hospital , Dalin Town, Chiayi , Taiwan 62247 ... . Acknowledgements This work was supported by grants from the National Science Council of Taiwan (NSC97-2320-B-415-002) and the Buddhist Tzuchi Dalin General Hospital (DTCRD97(2)-08). Author contribution Yi-wen LIU

Direct interaction of C/EBPδ and Sp1 at the GC-enriched promoter region synergizes the IL-10 gene transcription in mouse macrophage

We previously reported that LPS activates the transcription of the IL-10 gene through the Sp1 and C/EBP binding sites and indicated that Sp1, C/EBPβ and C/EBPδ can coactivate the IL-10 gene expression in mouse macrophage cells [Liu Y.-W., Tseng H.-P., Chen L.-C., Chen B.-K., Chang W.-C. J. Immunol. 171: 821–828, 2003]. In the present report, we demonstrated the direct physical...