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Comments on the twisted punctures of Aeven class S theory

Abstract We point out that the USp symmetry associated to a full twisted puncture of a class S theory of type Aeven has the global anomaly associated to π4(USp) = ℤ2. We discuss manifestations of this fact in the context of the superconformal field theory R2,2N introduced by Chacaltana, Distler and Trimm. For example, we find that this theory can be thought of as a natural...

Doxorubicin and anti-VEGF siRNA co-delivery via nano-graphene oxide for enhanced cancer therapy in vitro and in vivo

Doxorubicin and anti-VEGF siRNA co-delivery via nano-graphene oxide for enhanced cancer therapy in vitro and in vivo Qi Sun,1–3 Xiaoli Wang,1–3 Chunying Cui,1–3 Jing Li,1–3 Yifan Wang1–3 1Department of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing, China; 2Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Beijing, China...

Romans supergravity from five-dimensional holograms

Abstract We study five-dimensional superconformal field theories and their holographic dual, matter-coupled Romans supergravity. On the one hand, some recently derived formulae allow us to extract the central charges from deformations of the supersymmetric five-sphere partition function, whose large N expansion can be computed using matrix model techniques. On the other hand, the...

Doxorubicin-loaded redox-responsive micelles based on dextran and indomethacin for resistant breast cancer

Doxorubicin-loaded redox-responsive micelles based on dextran and indomethacin for resistant breast cancer Yunfang Zhou,1,* Shuanghu Wang,1,* Xuhua Ying,2 Yifan Wang,2 Peiwu Geng,1 Aiping Deng,3

DNA Self-assembly Catalyzed by Artificial Agents

Nucleic acids have been shown to be versatile molecules and engineered to produce various nanostructures. However, the poor rate of these uncatalyzed nucleic acid reactions has restricted the development and applications. Herein, we reported a novel finding that DNA self-assembly could be nonenzymatically catalyzed by artificial agents with an increasing dissociation rate...

(2, 2) superconformal bootstrap in two dimensions

We find a simple relation between two-dimensional BPS \( \mathcal{N}=2 \) superconformal blocks and bosonic Virasoro conformal blocks, which allows us to analyze the crossing equations for BPS 4-point functions in unitary (2, 2) superconformal theories numerically with semidefinite programming. We constrain gaps in the non-BPS spectrum through the operator product expansion of...

\( \mathcal{N} \) = 4 superconformal bootstrap of the K3 CFT

We study two-dimensional (4, 4) superconformal field theories of central charge c = 6, corresponding to nonlinear sigma models on K3 surfaces, using the superconformal bootstrap. This is made possible through a surprising relation between the BPS \( \mathcal{N} \) = 4 superconformal blocks with c = 6 and bosonic Virasoro conformal blocks with c = 28, and an exact result on the...

Short-term Internet search using makes people rely on search engines when facing unknown issues

The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day...

Growing Slowly 1 locus encodes a PLS-type PPR protein required for RNA editing and plant development in Arabidopsis

Most pentatricopeptide repeat (PPR) proteins are involved in organelle post-transcriptional processes, including RNA editing. The PPR proteins include the PLS subfamily, containing characteristic triplets of P, L, and S motifs; however, their editing mechanisms and roles in developmental processes are not fully understood. In this study, we isolated the Arabidopsis thaliana...

Hierarchical Task Planning for Multiarm Robot with Multiconstraint

Telecommunications, No. 10, Xitucheng Road, Haidian District, Beijing 100876, China Received 25 March 2016; Revised 12 July 2016; Accepted 27 July 2016 Academic Editor: Francisco Gordillo Copyright © 2016 Yifan ... Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original

Hierarchical Task Planning for Multiarm Robot with Multiconstraint

Telecommunications, No. 10, Xitucheng Road, Haidian District, Beijing 100876, China Received 25 March 2016; Revised 12 July 2016; Accepted 27 July 2016 Academic Editor: Francisco Gordillo Copyright © 2016 Yifan ... Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original

Solid-State Nanopore-Based DNA Sequencing Technology

The solid-state nanopore-based DNA sequencing technology is becoming more and more attractive for its brand new future in gene detection field. The challenges that need to be addressed are diverse: the effective methods to detect base-specific signatures, the control of the nanopore’s size and surface properties, and the modulation of translocation velocity and behavior of the...

miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer

, Shanshan Wang, Yifan Wang, Yanrong Yu, Meng Zhang, Keng Yuan & Weiping MinJiangxi Provincial Key Laboratory of Immunotherapy, Nanchang, ChinaZhigang Wang, Lu Xu, Yinying Hu, Yanqin Huang, Yujuan Zhang ... , Shanshan Wang, Yifan Wang, Yanrong Yu, Meng Zhang, Keng Yuan & Weiping MinDepartments of Surgery, Pathology, and Oncology, University of Western Ontario, London, CanadaXiufen Zheng & Weiping Min

Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway

Twist is a key transcription factor for Epithelial-mesenchymal transition (EMT), which is a cellular de-differentiation program that promotes invasion and metastasis, confers tumor cells with cancer stem cell (CSC)-like characteristics, and increases therapeutic resistance. However, the mechanisms that facilitate the functions of Twist remain unclear. Here we report that Twist...

Deformations with maximal supersymmetries part 2: off-shell formulation

Continuing our exploration of maximally supersymmetric gauge theories (MSYM) deformed by higher dimensional operators, in this paper we consider an off-shell approach based on pure spinor superspace and focus on constructing supersymmetric deformations beyond the first order. In particular, we give a construction of the Batalin-Vilkovisky action of an all-order non-Abelian Born...

Fault Diagnosis for a Multistage Planetary Gear Set Using Model-Based Simulation and Experimental Investigation

The gear damage will induce modulation effects in vibration signals. A thorough analysis of modulation sidebands spectral structure is necessary for fault diagnosis of planetary gear set. However, the spectral characteristics are complicated in practice, especially for a multistage planetary gear set which contains close frequency components. In this study, a coupled lateral and...

Fault Diagnosis for a Multistage Planetary Gear Set Using Model-Based Simulation and Experimental Investigation

The gear damage will induce modulation effects in vibration signals. A thorough analysis of modulation sidebands spectral structure is necessary for fault diagnosis of planetary gear set. However, the spectral characteristics are complicated in practice, especially for a multistage planetary gear set which contains close frequency components. In this study, a coupled lateral and...