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Piecewise Linear Weighted Iterative Algorithm for Beam Alignment in Scanning Beam Interference Lithography

To obtain a good interference fringe contrast and high fidelity, an automated beam iterative alignment is achieved in scanning beam interference lithography (SBIL). To solve the problem of alignment failure caused by a large beam angle (or position) overshoot exceeding the detector range while also speeding up the convergence, a weighted iterative algorithm using a weight...

Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance

Autophagy maintains homeostasis and is induced upon stress. Yet, its mechanistic interaction with oncogenic signaling remains elusive. Here, we show that in BRAFV600E-melanoma, autophagy is induced by BRAF inhibitor (BRAFi), as part of a transcriptional program coordinating lysosome biogenesis/function, mediated by the TFEB transcription factor. TFEB is phosphorylated and thus...

Towards an understanding of C9orf82 protein/CAAP1 function

, Mir Farshid Alemdehy, Fitriari Izzatunnisa Methodology: Muhammad Assad Aslam, Mir Farshid Alemdehy, Colin E. J. Pritchard, Ji Ying Song, Fitriari Izzatunnisa Muhaimin, Ruud H. Wijdeven, Ivo J. Huijbers ... . Project administration: Muhammad Assad Aslam, Mir Farshid Alemdehy, Heinz Jacobs. Resources: Muhammad Assad Aslam, Mir Farshid Alemdehy, Colin E. J. Pritchard, Ji-Ying Song, Ruud H. Wijdeven, Ivo J

Prognosis value of RBBP8 expression in plasma cell myeloma

contributed equally: Weilong Zhang, Ying Song, Xue He AffiliationsDepartment of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing, 100191, ChinaWeilong Zhang, Zuozhen Yang, Ping ... for Ying Song in:Nature Research journals • PubMed • Google Scholar Search for Xue He in:Nature Research journals • PubMed • Google Scholar Search for Xiaoni Liu in:Nature Research journals • PubMed

Evaporative deposition of polystyrene microparticles on PDMS surface

Evaporation of water and ethanol/water droplets containing large polystyrene (PS) microparticles on polydimethylsiloxane (PDMS) surface was experimentally investigated. It is found that no matter with or without small addition of ethanol, a compact monolayer deposition is formed for lower microparticle concentration while mountain-like deposition for higher concentration. Since...

Protective effect of hydroxysafflor yellow A against acute kidney injury via the TLR4/NF-κB signaling pathway

This study aimed to evaluate the protective effect of hydroxysafflor yellow A (HSYA) on ischemia/reperfusion (I/R)-induced acute kidney injury via the TLR4/NF-κB pathway, both in vitro and in vivo. Rats were subjected to removal of the right kidney and I/R injury to the left kidney. Rats subjected to renal I/R injury were treated with HSYA at 0.5 h prior to I/R injury. Renal...

RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly

, RAB GTPases regulate membrane functions through a switch between two distinct conformations: the GTP-bound ?on? Yue Sheng and Ying Song contributed equally to this work. and the GDP-bound ?off? forms ... and designed research. Yue Sheng, Ying Song and Rongjia Zhou analysed and interpreted the data and wrote the paper. Yue Sheng and Ying Song carried out the experimental work. Zhigang Li, Ying Song, Yabo

Protective Effects and Possible Mechanisms of Ergothioneine and Hispidin against Methylglyoxal-Induced Injuries in Rat Pheochromocytoma Cells

addressed to Tuzz-Ying Song; wt.ude.uyd.liam@77gnos Received 6 June 2017; Revised 8 August 2017; Accepted 23 August 2017; Published 17 October 2017 Academic Editor: Mohamed M. Abdel-Daim Copyright © 2017 ... Tuzz-Ying Song et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

Two-color heterodyne laser interferometry for long-distance stage measurement with correction of uncertainties in measured optical distances

Xiaotian Li Shan Jiang Ying Song Qiang Lv OPEN Published: xx xx xxxx We designed a new system that eliminates deviations by correcting uncertainty in optical distance measurements in the laser two-color ... the simulations, supervised by Wenhao Li and Bayanheshig. Ying Song and Shan Jiang helped write programs, Zhaowu Liu wrote the the manuscript, which was reviewed by Xiaotian Li and Qiang Lv. Additional

Age-Related Cutoffs of Plasma Aldosterone/Renin Concentration for Primary Aldosteronism Screening

. Disclosure Ying Song is the co-first author. Conflicts of Interest The authors declare that they have no conflicts of interest. Acknowledgments This study is funded by the National Key Clinical Specialties

Age-Related Cutoffs of Plasma Aldosterone/Renin Concentration for Primary Aldosteronism Screening

); and for those younger than 40 years old, an ARR of 1.0 (ng/dl)/(?IU/ml) might be more reasonable. Disclosure Ying Song is the co-first author. Conflicts of Interest The authors declare that they

Epothilone B impairs functional recovery after spinal cord injury by increasing secretion of macrophage colony-stimulating factor

The microtubule-stabilizing drug epothilone B (epoB) has shown potential value in the treatment of spinal cord injury (SCI) through diverse mechanisms. However, it remains elusive why a limited overall effect was observed. We aim to investigate the limiting factors underlying functional recovery promoted by epoB. The same SCI model treated by epoB was established as discussed...

Physical Activity and Sedentary Behaviors Modify the Association between Melanocortin 4 Receptor Gene Variant and Obesity in Chinese Children and Adolescents

Effects of MC4R variants in previous Chinese population studies were inconsistent. Gene-environment interactions might influence the effect of MC4R variants on obesity, which was still unclear. We performed the study to clarify the association of variants near MC4R gene with obesity-related phenotypes and gene-environment interactions in Chinese children and adolescents. Two...

Europium (III) chelate microparticle-based lateral flow immunoassay strips for rapid and quantitative detection of antibody to hepatitis B core antigen

(Grant No. 21575058). We would like to thank the National Natural Science Foundation of China. Author Contributions Rong-Liang Liang, Tian-Cai Liu, and Ying-Song Wu conceived and designed the experiment ... . Rong-Liang Liang, Qiao-Ting Deng, and Jun-Yu Liang performed the experiment. Rong-Liang Liang, Zhen-Hua Chen, and XuPing Xu analyzed the data and drafted the manuscript. Tian-Cai Liu and Ying-Song Wu

The Progress of Mitophagy and Related Pathogenic Mechanisms of the Neurodegenerative Diseases and Tumor

of Technology, Hangzhou Chaowang Road 18, Zhejiang 310014, China Received 2 August 2015; Revised 14 October 2015; Accepted 25 October 2015 Academic Editor: Pasquale Striano Copyright © 2015 Ying ... Song et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original

The Progress of Mitophagy and Related Pathogenic Mechanisms of the Neurodegenerative Diseases and Tumor

of Technology, Hangzhou Chaowang Road 18, Zhejiang 310014, China Received 2 August 2015; Revised 14 October 2015; Accepted 25 October 2015 Academic Editor: Pasquale Striano Copyright © 2015 Ying ... Song et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original

Elevated D-dimer and fibrinogen levels in serum of preoperative bone fracture patients

The changes of coagulation parameters in preoperative fracture patients reflect the coagulation status before surgery. We did retrospective assessment of preoperative fracture patients (n = 113) admitted to the hospital between September 2013 and September 2014. The control group were selected from healthy adults (n = 113) with matched age and gender. Platelet, PT INR, APTT...