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Equivalent circuit models for a biomembrane impedance sensor and analysis of electrochemical impedance spectra based on support vector regression

In this study, an electrochemical impedance biosensor was developed as a simple and fast method for real-time monitoring of biofilm binding properties via continuous impedance spectroscopy. To prepare the sensing membrane, cells were immobilized onto gold electrodes with nitrocellulose membranes. Different cell growth features were measured with the impedance instrument and...

Butenolide, a Marine-Derived Broad-Spectrum Antibiofilm Agent Against Both Gram-Positive and Gram-Negative Pathogenic Bacteria

Bacterial biofilm can cause nosocomial recurrent infections and implanted device secondary infections in patients and strongly promotes development of pathogenic drug resistance in clinical treatments. Butenolide is an effective anti-macrofouling compound derived from a marine Streptomyces sp., but its antibiofilm efficacy remains largely unexplored. In the present study, the...

DAXX promotes ovarian cancer ascites cell proliferation and migration by activating the ERK signaling pathway

The death-domain-associated protein (DAXX) was originally identified as a protein that binds to the transmembrane death receptor FAS and enhances both FAS-induced and transforming growth factor-β-dependent apoptosis. In a previous study, we found that nude mice injected with DAXX-overexpressing cells (ES-2-DAXX) accumulated large concentrations of first-generation ascites cells...

Multicompartment Ecosystem Mass Balances as a Tool for Understanding and Managing the Biogeochemical Cycles of Human Ecosystems

Nitrogen remains a ubiquitous pollutant in surface and groundwater throughout the United States, despite 30 years of pollution control efforts. A detailed multicompartment N balance for the Central Arizona-Phoenix ecosystem is used to illustrate how an ecosystem-level approach can be used to develop improved N management strategies. The N balance is used to demonstrate how...

Effects of climate and potential policy changes on heating degree days in current heating areas of China

Based on climate simulations over East Asia from a high-resolution regional climate model under RCP4.5 and 8.5 scenarios, we examine the impact of future climate change and heating policy changes on energy demand in current central heating areas over China using the heating degree days (HDD) and the number of the heating days (NHD) with different base temperature as the indices...

Simultaneous Quantification of Methotrexate and Its Metabolite 7-Hydroxy-Methotrexate in Human Plasma for Therapeutic Drug Monitoring

Xialan Zhang,1,4 Huamin Ding,1,5 Ying Xu,1,6 Hansheng Bai,1,7 Jing Liu,1,8 Xia Li,1,9 Shouhong Gao,1 Lifeng Huang,1 and Wansheng Chen1 1Department of Pharmacy, Changzheng Hospital, Second Military Medical

Elucidation and analyses of the regulatory networks of upland and lowland ecotypes of switchgrass in response to drought and salt stresses

University of Georgia for providing computing resources. We thank the JGI for pre-publication access to the genome of Panicum virgatum. Author Contributions Conceptualization: Chunman Zuo, Ying Xu. Data ... curation: Chunman Zuo, Yuhong Tang, Hao Fu. Formal analysis: Chunman Zuo, Yuhong Tang, Hao Fu, Ying Xu. Investigation: Chunman Zuo, Yuhong Tang, Ying Xu. Methodology: Chunman Zuo, Ying Xu. Project

The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells

BackgroundMillions of people are affected with retinal diseases that eventually cause blindness, and retinal progenitor cell (RPC) transplantation is a promising therapeutic avenue. However, RPC expansion and the underlying regulation mechanisms remain elusive.MethodsAdult mouse neural RPCs (mNRPCs) were isolated and amplified with the combination of basic fibroblast growth...

PhosContext2vec: a distributed representation of residue-level sequence contexts and its application to general and kinase-specific phosphorylation site prediction

Phosphorylation is the most important type of protein post-translational modification. Accordingly, reliable identification of kinase-mediated phosphorylation has important implications for functional annotation of phosphorylated substrates and characterization of cellular signalling pathways. The local sequence context surrounding potential phosphorylation sites is considered to...

A Laboratory Investigation into the Effects of Coarse Aggregate Angularity on Performance of WMA

This study evaluated the effects of coarse aggregate angularity (CAA) on the performances of warm mix asphalt (WMA) because previous studies have predominantly focused on the effects of CAA on the hot mix asphalt (HMA) performances. Five different CAAs were fabricated using Los Angeles abrasion test, and the digital image processing method was used to identify the CAA. Five mixes...

Relationship between high-sensitivity cardiac troponin T and the prognosis of elderly inpatients with non-acute coronary syndromes

Relationship between high-sensitivity cardiac troponin T and the prognosis of elderly inpatients with non-acute coronary syndromes Wei Wu,1 Dong-Xia Li,1 Qing Wang,2 Ying Xu,2 Yun-Jing Cui2 1General ... Ying Xu 0 Yun-Jing Cui 0 0 Department of geriatrics, Fuxing h ospital Affiliated to Capital Medical University , Beijing, People's republic of China 1 g eneral Practice Wards, Fuxing hospital Affiliated

Dynamic Behaviors in Coupled Neuron System with the Excitatory and Inhibitory Autapse under Electromagnetic Induction

The induced current produced by electromagnetic induction can adjust the membrane potential of neuron through the feedback of a magnetic flux-controlled memristor. We adopt the numerical simulation method with the aim of investigating the synchronous behavior in the neuronal system that is coupled by chemical and electrical synapses under electromagnetic induction. Within the...

Effects of Tai Chi Yunshou exercise on community-based stroke patients: a cluster randomized controlled trial

BackgroudTai Chi Chuan was used for stroke survivors with balance impairments. However, even a short-form of Tai Chi Chuan includes forms that make the exercise challenging for the stroke survivors. Tai Chi Yunshou (wave hands in the cloud) is the “mother” form and the fundamental form of all Tai Chi Chuan styles, which is considered more suitable and feasible for stroke...

Efficacy and Safety of Botulinum Toxin Type A in Treating Patients of Advanced Age with Idiopathic Trigeminal Neuralgia

? Contributions Jing Liu and Ying-Ying Xu contributed equally to this work. Acknowledgments /is work was funded by the National Natural Science Foundation (no. 81671270), the Youth Science and Technology Project

Effect of religion on hypertension in adult Buddhists and residents in China: A cross-sectional study

information AffiliationsDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, ChinaQingtao Meng, Ying Xu, Rufeng Shi, Xin Zhang, Si Wang, Kai Liu & Xiaoping Chen AuthorsSearch for ... Qingtao Meng in:Nature Research journals • PubMed • Google Scholar Search for Ying Xu in:Nature Research journals • PubMed • Google Scholar Search for Rufeng Shi in:Nature Research journals • PubMed

Collective responses in electrical activities of neurons under field coupling

AuthorsSearch for Ying Xu in:Nature Research journals • PubMed • Google Scholar Search for Ya Jia in:Nature Research journals • PubMed • Google Scholar Search for Jun Ma in:Nature Research journals • PubMed

Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem

, National Center for Nanoscience and Technology, Beijing, 100190, P.R. ChinaXuexiang Han, Yiye Li, Ying Xu, Xiao Zhao, Yinlong Zhang, Xiao Yang, Ruifang Zhao, Yuliang Zhao & Guangjun NieUniversity of Chinese ... Academy of Sciences, Beijing, 100049, P.R. ChinaXuexiang Han, Yiye Li, Ying Xu, Xiao Zhao, Yinlong Zhang, Xiao Yang, Ruifang Zhao, Yuliang Zhao & Guangjun NieDepartment of Chemistry, Tsinghua University

Herbal Compounds Play a Role in Neuroprotection through the Inhibition of Microglial Activation

Correspondence should be addressed to Yongjun Chen; moc.621@714jyhc and Ying Xu; moc.nuyila@3002216gniy Received 18 November 2017; Revised 13 February 2018; Accepted 5 March 2018; Published 17 April 2018 ... from General Program of National Natural Science Foundation of China (Grant 81274119 and 81773927 to Ying Xu and Grant 31571041 to Yongjun Chen) and Shanghai Municipal Health and Family Planning

Effects of timing on intracoronary autologous bone marrow-derived cell transplantation in acute myocardial infarction: a meta-analysis of randomized controlled trials

Background Several cell-based therapies for adjunctive treatment of acute myocardial infarction have been investigated in multiple clinical trials, but the timing of transplantation remains controversial. We conducted a meta-analysis of randomized controlled trials to investigate the effects of timing on bone marrow-derived cell (BMC) therapy in acute myocardial infarction (AMI...