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A multistage rotational speed changing molecular rotor regulated by pH and metal cations

 & Ying WangInstitute of Chemistry, Chinese Academy of Sciences, 100190, Beijing, ChinaGuangxia Wang, Qiaolian Li & Junfeng Xiang AuthorsSearch for Yingying Wu in:Nature Research journals • PubMed • Google

Toward a hybrid brain-computer interface based on repetitive visual stimuli with missing events

Background Steady-state visually evoked potentials (SSVEPs) can be elicited by repetitive stimuli and extracted in the frequency domain with satisfied performance. However, the temporal information of such stimulus is often ignored. In this study, we utilized repetitive visual stimuli with missing events to present a novel hybrid BCI paradigm based on SSVEP and omitted stimulus...

Average Consensus in Networks of Neutral Dynamical Agents with Fixed and Switching Topologies

This paper addresses the average consensus problem of neutral multiagent systems in undirected networks with fixed and switching topologies. For the case of fixed topology, necessary and sufficient conditions to average consensus are established by decoupling the neutral multiagent system in terms of the eigenvalues of the Laplacian matrix. For the case of switching topology...

Eye Movement Evidence for Hierarchy Effects on Memory Representation of Discourses

In this study, we applied the text-change paradigm to investigate whether and how discourse hierarchy affected the memory representation of a discourse. Three kinds of three-sentence discourses were constructed. In the hierarchy-high condition and the hierarchy-low condition, the three sentences of the discourses were hierarchically organized and the last sentence of each...

Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation

Out of the breast cancer subtypes, triple-negative breast cancer (TNBC) has the poorest prognosis without effective targeted therapies. Metformin, a first-line drug for type 2 diabetes mellitus, was demonstrated to target breast cancer stem cells selectively. However, the efficiency and the mechanism of action of metformin in TNBC are unclear. In this study, we demonstrated that...

CCL21/CCR7 Axis Contributed to CD133+ Pancreatic Cancer Stem-Like Cell Metastasis via EMT and Erk/NF-κB Pathway

Background Tumor metastasis is driven by malignant cells and stromal cell components of the tumor microenvironment. Cancer stem cells (CSCs) are thought to be responsible for metastasis by altering the tumor microenvironment. Epithelial-mesenchymal transition (EMT) processes contribute to specific stages of the metastatic cascade, promoted by cytokines and chemokines secreted by...

Evaluation of the new Chinese Disseminated Intravascular Coagulation Scoring System in critically ill patients: A multicenter prospective study

Disseminated intravascular coagulation (DIC) is a common life-threatening complication in critically ill patients. The diagnostic scoring systems of DIC enable a more prompt and accurate diagnosis of DIC, such as the International Society on Thrombosis and Haemostasis (ISTH), the Japanese Association for Acute Medicine (JAAM) and the Japanese Ministry of Health and Welfare (JMHW...

The role of chemotherapy and operation on lymphocytes accumulation in peripheral blood obtained from patients with oral squamous cell carcinoma

The “Cancer Immunoediting” concept has provided critical insights suggesting dual functions of immune system during the cancer initiation and development. However, the dynamics and roles of CD4+ and CD8+ T cells, CD19+ B cells, and CD56+ NK cells in the patients with oral squamous cell carcinoma during treatment remain unclear. A total of 43 patients with OSCC were divided into...

Assessment for Fuel Consumption and Exhaust Emissions of China’s Vehicles: Future Trends and Policy Implications

Environmental Science and Engineering, Tianjin University, Tianjin 300072, China Received 7 September 2012; Accepted 1 November 2012 Academic Editors: B. Chen and Z.-M. Chen Copyright © 2012 Yingying Wu et al

Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells

The initiation and progression of various solid tumors, including pancreatic carcinoma, are driven by a population of cells with stem cell properties, namely cancer stem cells (CSCs). Like their normal counterparts, CSCs are also believed to rely on their own microenvironment termed niches to sustain the population. Hypoxia-inducible factor-1α (HIF-1α) is a major actor in the...

TSP1-producing B cells show immune regulatory property and suppress allergy-related mucosal inflammation

, No. JC201005250073A). Author information Author notesHuan-Ping Zhang & Yingying Wu These authors contributed equally to this work. AffiliationsShenzhen Key Laboratory of Allergy & Immunology ... , Xiao-Rui Geng, Gui Yang & Zhi-Qiang Liu AuthorsSearch for Huan-Ping Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Yingying Wu in:Nature Research journals • PubMed • Google