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6 papers found.
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New momentum and energy balance equations considering kinetic energy effect for mathematical modelling of a fixed bed adsorption column

It was aimed to derive rigorous momentum and energy balance equations where the change of kinetic energy in both spatial and temporal domains of a fixed-bed adsorption column was newly taken into account. While the effect of kinetic energy on adsorption column dynamics is negligible in most cases, it can become more and more influential with an adsorption column experiencing a...

Pharmacokinetic comparison of sustained- and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers

Pharmacokinetic comparison of sustained- and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers Yo Han Kim,1 Jong-Lyul Ghim,2 Jin Ah Jung,2

Pharmacokinetic interaction between udenafil and dapoxetine: a randomized, open-labeled crossover study in healthy male volunteers

Pharmacokinetic interaction between udenafil and dapoxetine: a randomized, open-labeled crossover study in healthy male volunteers Yo Han Kim,1 Hee Youn Choi,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Hyeong

Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers

Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers Yo Han Kim,1 Hee Youn Choi,1 Shi Hyang Lee,1 Hyeong-Seok Lim,1 Tokutaro Miki,2 Jong

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers Yo Han Kim,1 Hee Youn Choi,1 Hyeong-Seok Lim,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Donghyun Hong,2 Seong Su Kim

Evaluation of Pharmacokinetic Drug Interactions Between Gemigliptin (Dipeptidylpeptidase-4 Inhibitor) and Glimepiride (Sulfonylurea) in Healthy Volunteers

PurposeGemigliptin is approved for the treatment of type II diabetes mellitus. Sulfonylureas are commonly used in combination with other antidiabetic drugs to improve glycemic control. The objective of this study was to evaluate the pharmacokinetics, safety, and tolerability of gemigliptin and glimepiride combination therapy compared with those of monotherapies.MethodsA...