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Correction: Short-term anti-proteinuric effect of tacrolimus is not related to preservation of the glomerular filtration rate in IgA nephropathy: A 5-year follow-up study

-Chul Kim Ho Suk Koo Ho Jun Chin The x-axis labels for Fig 2D are cut-off. The x-axis labels for Fig 3B are incorrect. Please see the correct Fig 2 and Fig 3 here. OPEN ACCESS - Copyright: © 2018 Yu et

Short-term anti-proteinuric effect of tacrolimus is not related to preservation of the glomerular filtration rate in IgA nephropathy: A 5-year follow-up study

Contributions Conceptualization: Mi-yeon Yu, Yong-Chul Kim, Ho Jun Chin. Data curation: Mi-yeon Yu, Yong-Chul Kim, Ho Jun Chin. Formal analysis: Ho Suk Koo, Ho Jun Chin. 10 / 12 Methodology: Ho Jun Chin

Death with graft function after kidney transplantation: a single-center experience

Background Death with graft function (DWGF) is an important cause of long-term loss of grafts and patients. In this study, we investigated clinical characteristics and causes of DWGF in kidney transplant recipients. Methods We recruited kidney allograft recipients who underwent surgery during 1973–2016 at Seoul National University Hospital in Korea (n = 2137). We divided...

Soluble cMet levels in urine are a significant prognostic biomarker for diabetic nephropathy

Biomedical Research Institute, Seoul, KoreaSeung Hee Yang AuthorsSearch for Yong Chul Kim in:Nature Research journals • PubMed • Google Scholar Search for Jung Nam An in:Nature Research journals • PubMed

Effect of post-transplant glycemic control on long-term clinical outcomes in kidney transplant recipients with diabetic nephropathy: A multicenter cohort study in Korea

. Supporting information S1 File. Individual patient information. (XLSX) Author Contributions Conceptualization: Yong Chul Kim, Nara Shin, Young Hoon Kim, Hyosang Kim, Jang-Hee Cho, Chan-Duck Kim, Dong-Wan ... Chae, Jung Pyo Lee. Data curation: Nara Shin, Young Hoon Kim, Jang-Hee Cho, Chan-Duck Kim, Jongwon Ha. Formal analysis: Yong Chul Kim, Nara Shin, Sunhwa Lee, Jung Pyo Lee, Yon Su Kim. Methodology

Association between post-transplant red cell distribution width and prognosis of kidney transplant recipients

for Young Hoon Kim in:Nature Research journals • PubMed • Google Scholar Search for Yong Chul Kim in:Nature Research journals • PubMed • Google Scholar Search for Mi-Yeon Yu in:Nature Research

Impaired insula functional connectivity associated with persistent pain perception in patients with complex regional pain syndrome

Given that the insula plays a contributory role in the perception of chronic pain, we examined the resting-state functional connectivity between the insular cortex and other brain regions to investigate neural underpinnings of persisting perception of background pain in patients with complex regional pain syndrome (CRPS). A total of 25 patients with CRPS and 25 matched healthy...

Opioid sparing effect and safety of nefopam in patient controlled analgesia after laparotomy: A randomized, double blind study

Objectives A double-blind randomised study to evaluate the opioid sparing effect and safety of nefopam when administered via intravenous patient controlled analgesia (PCA) with fentanyl.

Elevated bilirubin levels are associated with a better renal prognosis and ameliorate kidney fibrosis

Background Bilirubin has been reported to protect against kidney injury. However, further studies highlighting the beneficial effects of bilirubin on renal fibrosis and chronic renal function decline are necessary. Methods We assessed a prospective cohort with a reference range of total bilirubin levels. The primary outcome was a 30% reduction in the estimated glomerular...

Early onset hyperuricemia is a prognostic marker for kidney graft failure: Propensity score matching analysis in a Korean multicenter cohort

It remains inconclusive whether hyperuricemia is a true risk factor for kidney graft failure. In the current study, we investigated the association of hyperuricemia and graft outcome. We performed a multi-center cohort study that included 2620 kidney transplant recipients. The patients were classified as either normouricemic or hyperuricemic at 3 months after transplantation...

Early dialysis initiation does not improve clinical outcomes in elderly end-stage renal disease patients: A multicenter prospective cohort study

Background The optimal timing for initiating dialysis in end-stage renal disease (ESRD) is controversial, especially in the elderly. Methods 665 patients ≥65 years old who began dialysis from August 2008 to February 2015 were prospectively enrolled in the Clinical Research Center for End-Stage Renal Disease cohort study. Participants were divided into 2 groups based on the median...

Photoplethysmographic signals to predict the success of lumbar sympathetic blockade for lower extremity pain

Objective A prospective, observational study to investigate how photoplethysmography (PPG) signals change during lumbar sympathetic blockade (LSB), and whether these changes can predict sympathetically mediated pain (SMP).

Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy

nephropathy patients who are not able to tolerate anti-hypertensive medication. Supporting Information Protocol for this clinical trial. CONSORT Checklist. Acknowledgments Yong-Chul Kim contributed to

Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment

JungIn Um Youngha Seo Wan Seok Kang Suk-Won Jin Min Chul Kim Yong-Chul Kim Da-Woon Jung Darren R. Williams Youngkeun Ahn OPEN The cardiac microenvironment includes cardiomyocytes, fibroblasts and

Down-Regulation of Hydrogen Sulfide Biosynthesis Accompanies Murine Interstitial Cells of Cajal Dysfunction in Partial Ileal Obstruction

Purpose To investigate the role of endogenous hydrogen sulfide (H2S) in partial obstruction-induced dysfunction of the interstitial cells of Cajal (ICC) in mice ileum. Materials and Methods Partial intestinal obstruction was induced surgically in male imprinting control region (ICR) mice. ICC networks were studied by Immunohistochemistry. Electrical activity was recorded by...

Trends in the prevalence of chronic kidney disease, other chronic diseases and health-related behaviors in an adult Korean population: data from the Korean National Health and Nutrition Examination Survey (KNHANES)

Background. Chronic kidney disease (CKD) is an increasing public health problem. However, there have been limited data on the trend of CKD prevalence, along with the changes of health-related behaviors and other chronic diseases in an adult Korean population. Methods. Data from the Korean National Health and Nutrition Examination Survey in 2005 and 2007 were analyzed. The study...

Antiviral Activity of Coxsackievirus B3 3C Protease Inhibitor in Experimental Murine Myocarditis

Background. We investigated the efficacy of a 3C protease inhibitor (3CPI) in a murine coxsackievirus B3 (CVB3) myocarditis model. CVB3 is a primary cause of viral myocarditis. The CVB3 genome encodes a single polyprotein that undergoes a series of proteolytic events to produce several viral proteins. Most of this proteolysis is catalyzed by the 3C protease (3CP). Methods and...

Mild decrease in estimated glomerular filtration rate and proteinuria are associated with all-cause and cardiovascular mortality in the general population

Background. A recent collaborative meta-analysis by Kidney Disease: Improving Global Outcomes reported that an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m2 and an albumin-to-creatinine ratio of ≥10 mg/g were independent predictors for mortality in the general population. However, selection bias, heterogeneity of the cohorts and measurement issues could be...

Glycated haemoglobin and the incidence of end-stage renal disease in diabetics

Background. The relationship between glycated haemoglobin and the incidence of end-stage renal disease (ESRD) in patients with diabetes remains uncertain, especially in those with decreased glomerular filtration rate (GFR). The aim of this study was to assess the appropriate HbA1c level for diabetics for minimizing the incidence of ESRD and all-cause mortality. Methods. A cohort...