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Caffeoylquinic Acid-Rich Extract of Aster glehni F. Schmidt Ameliorates Nonalcoholic Fatty Liver through the Regulation of PPARδ and Adiponectin in ApoE KO Mice

; Published 23 October 2017 Academic Editor: Henrike Sell Copyright © 2017 Yong-Jik Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits ... paper. Authors’ Contributions Yong-Jik Lee designed the research, performed all experiments, and wrote the manuscript. Yoo-Na Jang, Yoon-Mi Han, Hyun-Min Kim, and Jong-Min Jeong were involved in animal

Caffeoylquinic Acid-Rich Extract of Aster glehni F. Schmidt Ameliorates Nonalcoholic Fatty Liver through the Regulation of PPARδ and Adiponectin in ApoE KO Mice

; Published 23 October 2017 Academic Editor: Henrike Sell Copyright © 2017 Yong-Jik Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits ... paper. Authors’ Contributions Yong-Jik Lee designed the research, performed all experiments, and wrote the manuscript. Yoo-Na Jang, Yoon-Mi Han, Hyun-Min Kim, and Jong-Min Jeong were involved in animal

Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions

February 2017; Accepted 19 February 2017; Published 13 March 2017 Academic Editor: Brian N. Finck Copyright © 2017 Yong-Jik Lee et al. This is an open access article distributed under the Creative Commons

Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions

February 2017; Accepted 19 February 2017; Published 13 March 2017 Academic Editor: Brian N. Finck Copyright © 2017 Yong-Jik Lee et al. This is an open access article distributed under the Creative Commons

Development of a keratinase activity assay using recombinant chicken feather keratin substrates

Poultry feathers consist mainly of the protein keratin, which is rich in β-pleated sheets and consequently resistant to proteolysis. Although many keratinases have been identified, the reasons for their substrate specificity towards β-keratin remain unclear due to difficulties in preparing a soluble feather keratin substrate for use in activity assays. In the present study, we...

Genome sequence of a native-feather degrading extremely thermophilic Eubacterium, Fervidobacterium islandicum AW-1

Fervidobacterium islandicum AW-1 (KCTC 4680) is an extremely thermophilic anaerobe isolated from a hot spring in Indonesia. This bacterium could degrade native chicken feathers completely at 70 °C within 48 h, which is of potential importance on the basis of relevant environmental and agricultural issues in bioremediation and development of eco-friendly bioprocesses for the...

Cholesterol-Induced Non-Alcoholic Fatty Liver Disease and Atherosclerosis Aggravated by Systemic Inflammation

Although triglyceride accumulation in the liver causes non-alcoholic fatty liver disease (NAFLD), hypercholesterolemia is also a main cause of NAFLD as well as atherosclerosis. However, NAFLD and atherosclerosis have not been investigated simultaneously in animal models fed a high-cholesterol diet. Moreover, it is unclear whether systemic inflammation can exacerbate both...