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12 papers found.
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Epithelioid hemangioendothelioma of the thyroid: a case report

Background Epithelioid hemangioendothelioma (EHE) of the thyroid is an extremely rare disease; only three cases have been reported in the English literature to date. Here, we describe a case involving a patient with thyroid EHE successfully treated with curative surgery. Case presentation A 74-year-old woman presented with a right thyroid mass. The nodule was approximately 2 cm...

Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women

Background Although global hypomethylation of leukocyte DNA has been associated with an increased risk of several sites of cancer, including breast cancer, determinants of global methylation level among healthy individuals remain largely unexplored. Here, we examined whether postmenopausal endogenous sex hormones were associated with the global methylation level of leukocyte DNA...

Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan

Background Although the associations between grilled (broiled) or barbecued meats or fish intake and stomach cancer risk have been investigated, the evidence implicating heterocyclic amine (HCA) intake as a cause of stomach cancer is limited. We conducted a case-control study to investigate the association between HCA intake and stomach cancer risk. We also investigated the...

Comparison of postmenopausal endogenous sex hormones among Japanese, Japanese Brazilians, and non-Japanese Brazilians

Motoki Iwasaki 0 Yoshio Kasuga 2 Shiro Yokoyama 1 Hiroshi Onuma 1 Hideki Nishimura 7 Ritsu Kusama 6 Gerson Shigeaki Hamada 5 Ines Nobuko Nishimoto 4 Maria do Socorro Maciel 9 Juvenal Motola Jr 8 Fbio

Comparison of postmenopausal endogenous sex hormones among Japanese, Japanese Brazilians, and non-Japanese Brazilians

Differences in sex hormone levels among populations might contribute to the variation in breast cancer incidence across countries. Previous studies have shown higher breast cancer incidence and mortality among Japanese Brazilians than among Japanese. To clarify the difference in hormone levels among populations, we compared postmenopausal endogenous sex hormone levels among...

Association of CYP19A1 polymorphisms with risks for atypical adenomatous hyperplasia and bronchioloalveolar carcinoma in the lungs

3 4 Motoki Iwasaki 1 4 Taiki Yamaji 1 4 Hideo Kunitoh 0 4 13 Kenji Suzuki 4 8 11 Yoko Shimada 4 Kouya Shiraishi 4 Yoshio Kasuga 4 7 Gerson Shigeaki Hamada 4 6 Koh Furuta 4 5 Koji Tsuta 4 10 Hiromi

Genetic polymorphisms in estrogen metabolism and breast cancer risk in case–control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians

Motoki Iwasaki 1 Yoshio Kasuga 2 Shiro Yokoyama 3 Hiroshi Onuma 3 Hideki Nishimura 4 Ritsu Kusama 5 Gerson Shigeaki Hamada 6 Ines Nobuko Nishimoto 7 Hirofumi Iyeyasu 8 Juvenal Motola Jr 9 Fa? bio Martins

Association of Helicobacter pylori infection and environmental factors in non-cardia gastric cancer in Japan

Although Helicobacter pylori infection is a major risk factor for gastric cancer, it does not explain the full picture of stomach carcinogenesis. There have been few epidemiological studies, however, which examined both H. pylori and environmental factors simultaneously. The aims of this study were to estimate the association of environmental factors (smoking and dietary factors...

A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus

Hong Tao Kazuya Shinmura Tomoyuki Hanaoka Syusuke Natsukawa Kozo Shaura Yoichi Koizumi Yoshio Kasuga Takachika Ozawa Toshimasa Tsujinaka Zhongyou Li Satoru Yamaguchi Jun Yokota Haruhiko Sugimura

Identification of a Functional Genetic Variant at 16q12.1 for Breast Cancer Risk: Results from the Asia Breast Cancer Consortium

. Shrubsole Ui Soon Khoo Kelvin Y. K. Chan Sum Yin Chan Christopher A. Haiman Brian E. Henderson Loic Le Marchand Motoki Iwasaki Yoshio Kasuga Shoichiro Tsugane Keitaro Matsuo Kazuo Tajima Hiroji Iwata Bo Huang

Genome-Wide Association Study in East Asians Identifies Novel Susceptibility Loci for Breast Cancer

Hidemi Ito Yoshio Kasuga Sei-Hyun Ahn Han Sung Kang Kelvin Y. K. Chan Hiroji Iwata Shoichiro Tsugane Chun Li Xiao- Ou Shu Dae-Hee Kang Wei Zheng Mark I. McCarthy, University of Oxford, United Kingdom

Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium

Yoshio Kasuga 10 Wenjing Wang 17 Jia-Rong Cheng 0 Keun-Young Yoo 23 Jong-Young Lee 9 Hong Zheng 26 Yao Liu 25 Ya-Lan Shieh 19 Sung-Won Kim 11 Jong Won Lee 12 Hiroji Iwata 13 Loic Le Marchand 14 Sum Yin