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Which brain lesions produce spasticity? An observational study on 45 stroke patients

the sum for muscle tone in lower extremity after stroke. (DOCX) Author Contributions Conceptualization: Kyoung Bo Lee, Bo Young Hong, Seong Hoon Lim. Data curation: Kyoung Bo Lee, Sang Cheol Yoon ... , Eun-Kyu Ji, Dong Baek Son, Seong Hoon Lim. Funding acquisition: Seong Hoon Lim. Investigation: Kyoung Bo Lee. Methodology: Kyoung Bo Lee. Resources: Bo Young Hong, Joon Sung Kim, Bomi Sul

Relationship between dementia and ankylosing spondylitis: A nationwide, population-based, retrospective longitudinal cohort study

Lee, Seung-Woo Suh, Jae-Hyuk Yang, Jae-Young Hong. Data curation: Dae Woong Kim, Kyungdo Han, Sung-Woo Choi, Jae-Hyuk Yang, Si-Young Park. Formal analysis: Kyungdo Han, Jae-Hyuk Yang. Funding ... acquisition: Byung-Joon Shin, Si-Young Park, Jae-Young Hong. Investigation: Hae-Dong Jang, Jin-Sung Park, Dae Woong Kim, Byung-Joon Shin, Jae Chul Lee, Sung-Woo Choi, Seung-Woo Suh, Whi Je Cho. Methodology

Trends in the prevalence and incidence of ankylosing spondylitis in South Korea, 2010–2015 and estimated differences according to income status

-Young Hong in:Nature Research journals • PubMed • Google Scholar Search for Ye-Soo Park in:Nature Research journals • PubMed • Google Scholar Search for Kyungdo Han in:Nature Research journals • PubMed ... . Corresponding author Correspondence to Jae-Young Hong. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing

eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B

The initiator tRNA (Met-tRNA i Met ) at the P site of the small ribosomal subunit plays an important role in the recognition of an mRNA start codon. In bacteria, the initiator tRNA carrier, IF2, facilitates the positioning of Met-tRNA i Met on the small ribosomal subunit. Eukarya contain the Met-tRNA i Met carrier, eIF2 (unrelated to IF2), whose carrier activity is inhibited...

Approaches to identify and characterize microProteins and their potential uses in biotechnology

Bhati , Anko Blaakmeer, Esther Botterweg Paredes, Ulla Dolde, Tenai Eguen, Shin-Young Hong, Vandasue Rodrigues, Daniel Straub, Bin Sun and Stephan Wenkel are 3 Stephan Wenkel MicroProteins are small

Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver

The present study aimed to investigate whether scopolin exhibits beneficial effects on high-fat diet (HFD)-induced hepatic steatosis in mice. The involvement of sirtuin 1 (SIRT1) as a molecular target for scopolin was also explored. Scopolin decreased the Km of SIRT1 for p53 and nicotinamide adenine dinucleotide without altering Vmax in a cell-free system. Scopolin alleviated...

Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation

regulation Mark Borris D Aldonza Ji-Young Hong Sang Kook Lee Chemotherapy-induced cancer cell secretomes promote resistance due, in part, to a predominant glycolytic energy metabolism, which drives

Assessing Seasonal and Inter-Annual Variations of Lake Surface Areas in Mongolia during 2000-2011 Using Minimum Composite MODIS NDVI

A minimum composite method was applied to produce a 15-day interval normalized difference vegetation index (NDVI) dataset from Moderate Resolution Imaging Spectroradiometer (MODIS) daily 250 m reflectance in the red and near-infrared bands. This dataset was applied to determine lake surface areas in Mongolia. A total of 73 lakes greater than 6.25 km2in area were selected, and 28...

Red cell distribution width as a novel marker for predicting high-risk from upper gastro-intestinal bleeding patients

curation: Sin Young Kim, Dae Young Hong, Jong Won Kim. Formal analysis: Kyeong Ryong Lee, Sang O. Park. Investigation: Kyeong Ryong Lee, Sang O. Park. Methodology: Kyeong Ryong Lee. Project ... Kim, Young Hwan Lee. 10 / 12 Writing ± original draft: Kyeong Ryong Lee, Sang O. Park. Writing ± review & editing: Kyeong Ryong Lee, Sang O. Park, Dae Young Hong, Kwang Je Baek, Dong Hyuk Shin

Incidence of and risk factors for glaucoma in lost-to-follow-up normal-tension glaucoma suspect patients

Background To investigate the incidence and risk factors of glaucoma in normal-tension glaucoma (NTG) suspect patients who had been lost-to-follow-up for at least 24 months. Methods Seventy-two eyes of 72 NTG suspect patients who returned to the hospital after at least 24 months of follow-up loss were enrolled in this study between January 2009 and June 2013. The data were...

Affordable care act: comparison of healthcare indicators among different insurance beneficiaries with new coverage eligibility

Background Health coverage in the United States will be increased to nearly universal levels under the Affordable Care Act (ACA). In order to better understand the impact of the type of health insurance and health outcomes, there is a need to examine health disparities and inequalities between the insured and the uninsured based on their eligibility for coverage. Methods The...

See-through optical combiner for augmented reality head-mounted display: index-matched anisotropic crystal lens

AffiliationsSchool of Electrical and Computer Engineering, Seoul National University, Gwanak-Gu Gwanakro 1, Seoul, 08826, South KoreaJong-Young Hong, Chang-Kun Lee, Seungjae Lee, Byounghyo Lee, Dongheon Yoo, Changwon ... Jang, Jonghyun Kim, Jinsoo Jeong & Byoungho Lee AuthorsSearch for Jong-Young Hong in:Nature Research journals • PubMed • Google Scholar Search for Chang-Kun Lee in:Nature Research journals • PubMed

Winter climate changes over East Asian region under RCP scenarios using East Asian winter monsoon indices

The changes in the winter climatology and variability of the East Asian winter monsoon (EAWM) for the late 21st century (2070–2099) under the Representative Concentration Pathway (RCP) 4.5 and 8.5 scenarios are projected in terms of EAWM indices (EAWMIs). Firstly, the capability of the climate models participating in the Coupled Model Intercomparison Project phase 5 (CMIP5) in...

Characterization of Neurogenic Potential of Dental Pulp Stem Cells Cultured in Xeno/Serum-Free Condition: In Vitro and In Vivo Assessment

Neural stem cells (NSCs) have a high potency for differentiation to neurons and glial cells for replacement of damaged cells and paracrine effects for the regeneration and remyelination of host axons. Dental pulp is known to have a potential to differentiate into neural-like cells; therefore, dental pulp may be used as an autologous cell source for neural repair. In this study...

Characterization of Neurogenic Potential of Dental Pulp Stem Cells Cultured in Xeno/Serum-Free Condition: In Vitro and In Vivo Assessment

Neural stem cells (NSCs) have a high potency for differentiation to neurons and glial cells for replacement of damaged cells and paracrine effects for the regeneration and remyelination of host axons. Dental pulp is known to have a potential to differentiate into neural-like cells; therefore, dental pulp may be used as an autologous cell source for neural repair. In this study...

Characterization of Neurogenic Potential of Dental Pulp Stem Cells Cultured in Xeno/Serum-Free Condition: In Vitro and In Vivo Assessment

Neural stem cells (NSCs) have a high potency for differentiation to neurons and glial cells for replacement of damaged cells and paracrine effects for the regeneration and remyelination of host axons. Dental pulp is known to have a potential to differentiate into neural-like cells; therefore, dental pulp may be used as an autologous cell source for neural repair. In this study...

An mRNA-specific tRNAi carrier eIF2A plays a pivotal role in cell proliferation under stress conditions: stress-resistant translation of c-Src mRNA is mediated by eIF2A

c-Src, a non-receptor protein tyrosine kinase, activates NF-κB and STAT3, which in turn triggers the transcription of anti-apoptosis- and cell cycle-related genes. c-Src protein regulates cell proliferation, cell motility and programmed cell death. And the elevated level of activated c-Src protein is related with solid tumor generation. Translation of c-Src mRNA is directed by an...

Quality of Life Analysis and Smoking Correlation in Symptomatic Spine Osteoarthritis: A Nationwide Health Survey Analysis of an Elderly Population with EQ-5D

Objectives To analyze quality of life in people with symptomatic spine osteoarthritis (OA) using the results of a cross-sectional, nationwide survey. Materials and Methods This study used data from the Fifth Korean National Health and Nutrition Examination Survey (KNHANES V-5; 2010–2012). After excluding ineligible subjects, the total number of subjects in the study was 8,963...

Relationship between bone mineral density and alcohol intake: A nationwide health survey analysis of postmenopausal women

Objectives Among a variety of relevant factors of osteoporosis, the association between alcohol intake and postmenopausal women’s bone mineral density (BMD) by using data from the Korean National Health and Nutrition Examination Survey was evaluated in this study. Materials and methods Among a total of 31,596 subjects, males, premenopausal women, participants without BMD data...

Synteny Portal: a web-based application portal for synteny block analysis

Recent advances in next-generation sequencing technologies and genome assembly algorithms have enabled the accumulation of a huge volume of genome sequences from various species. This has provided new opportunities for large-scale comparative genomics studies. Identifying and utilizing synteny blocks, which are genomic regions conserved among multiple species, is key to...