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The risk of cognitive impairment associated with hearing function in older adults: a pooled analysis of data from eleven studies

Impaired hearing and cognition are disabling conditions among older adults. Research has presented inconsistent conclusions regarding hearing impairment posing a risk for cognitive impairment. We aimed to assess this from published evidence via searching PubMed and Embase, from the inception of the databases indexed to December 2, 2016. For those high-quality studies retrieved...

Two types of weight-dependent walks with a trap in weighted scale-free treelike networks

In this paper, we present the weighted scale-free treelike networks controlled by the weight factor r and the parameter m. Based on the network structure, we study two types of weight-dependent walks with a highest-degree trap. One is standard weight-dependent walk, while the other is mixed weight-dependent walk including both nearest-neighbor and next-nearest-neighbor jumps...

The entire mean weighted first-passage time on a family of weighted treelike networks

In this paper, we consider the entire mean weighted first-passage time (EMWFPT) with random walks on a family of weighted treelike networks. The EMWFPT on weighted networks is proposed for the first time in the literatures. The dominating terms of the EMWFPT obtained by the following two methods are coincident. On the one hand, using the construction algorithm, we calculate the...

Inhibition of cyclooxygenase-2 by NS398 attenuates noise-induced hearing loss in mice

Otolaryngology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, PR ChinaWenxue Tang AuthorsSearch for Yu Sun in:Nature Research journals • PubMed • Google ScholarSearch for Jintao Yu ... interests. Corresponding authors Correspondence to Yu Sun or Wenxue Tang. Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other

Malignancy risk stratification of thyroid nodules: comparisons of four ultrasound Thyroid Imaging Reporting and Data Systems in surgically resected nodules

, 200072, ChinaYing Wang, Ya-Ping He, Xiao-Long Li, Wei-Wei Ren, Chong-Ke Zhao, Xiao-Wan Bo, Dan Wang, Cheng-Yu Sun & Hui-Xiong XuDepartment of Medical Ultrasound, Yangpu Hospital, Tongji University School ... Zhao, Xiao-Wan Bo, Dan Wang, Cheng-Yu Sun & Hui-Xiong XuShanghai Center for Thyroid Diseases, Shanghai, 200072, ChinaYing Wang, Ya-Ping He, Xiao-Long Li, Wei-Wei Ren, Chong-Ke Zhao, Xiao-Wan Bo, Dan Wang

Human sperm rheotaxis: a passive physical process

A long-standing question in natural reproduction is how mammalian sperm navigate inside female reproductive tract and finally reach the egg cell, or oocyte. Recently, fluid flow was proposed as a long–range guidance cue for sperm navigation. Coitus induces fluid flow from oviduct to uterus, and sperm align themselves against the flow direction and swim upstream, a phenomenon...

Microfluidic Assessment of Frying Oil Degradation

journals • PubMed • Google ScholarSearch for Yu Sun in:Nature Research journals • PubMed • Google Scholar Contributions M.L., S.X., C.R., J.L. and Y.S. conceived and designed the project. M.L., Z.X. and Z.W ... no competing financial interests. Corresponding authors Correspondence to Shaorong Xie or Jun Luo or Yu Sun. Supplementary information PDF files1.Supplementary Information 2.Supplementary

Distribution pattern of left-ventricular myocardial strain analyzed by a cine MRI based deformation registration algorithm in healthy Chinese volunteers

The cine magnetic resonance imaging based technique feature tracking-cardiac magnetic resonance (FT-CMR) is emerging as a novel, simple and robust method to evaluate myocardial strain. We investigated the distribution characteristics of left-ventricular myocardial strain using a novel cine MRI based deformation registration algorithm (DRA) in a cohort of healthy Chinese subjects...

Lateralization of gene expression in the honeybee brain during olfactory learning

In the last decade, it has been demonstrated that brain functional asymmetry occurs not only in vertebrates but also in invertebrates. However, the mechanisms underlying functional asymmetry remain unclear. In the present study, we trained honeybees of the same parentage and age, on the proboscis extension reflex (PER) paradigm with only one antenna in use. The comparisons of...

Predictable Chronic Mild Stress during Adolescence Promotes Fear Memory Extinction in Adulthood

Early-life stress in adolescence has a long-lasting influence on brain function in adulthood, and it is mostly recognized as a predisposing factor for mental illnesses, such as anxiety and posttraumatic stress disorder. Previous studies also indicated that adolescent predictable chronic mild stress (PCMS) in early life promotes resilience to depression- and anxiety-like behaviors...

Dietary legume consumption reduces risk of colorectal cancer: evidence from a meta-analysis of cohort studies

20130142110017 for Xiaoping Miao and The National Natural Science Foundation of China (NSCF-81222038). Author information Author notesBeibei Zhu & Yu Sun These authors contributed equally to this work ... (Wuhan), and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaBeibei Zhu, Yu Sun, Rong Zhong

Diagnostic Application of Targeted Next-Generation Sequencing of 80 Genes Associated with Disorders of Sexual Development

Institute for Pediatric Research, Shanghai, 200092, ChinaYanjie Fan, Xia Zhang, Lili Wang, Ruifang Wang, Zhuo Huang, Yu Sun, Jun Ye, Lianshu Han, Wenjuan Qiu, Huiwen Zhang, Lili Liang, Xuefan Gu & Yongguo ... Ruifang Wang in:Nature Research journals • PubMed • Google ScholarSearch for Zhuo Huang in:Nature Research journals • PubMed • Google ScholarSearch for Yu Sun in:Nature Research journals • PubMed • Google

A C-terminally truncated mouse Best3 splice variant targets and alters the ion balance in lysosome-endosome hybrids and the endoplasmic reticulum

Author notesLichang Wu & Yu Sun These authors contributed equally to this work. AffiliationsDepartment of Animal Sciences and Technology, Qingdao Agricultural University, Qingdao, ChinaLichang Wu, Qingjie ... Pan, Huanqi Liu & Yinchuan LiCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, ChinaLichang Wu, Yu Sun, Liqiao Ma, Jun Zhu, Baoxia Zhang, Yuyin Li & Aipo Diao

Virtual touch tissue imaging and quantification (VTIQ) in the evaluation of thyroid nodules: the associated factors leading to misdiagnosis

National Natural Scientific Foundation of China (Grants 81401417 and 81501475). Author information Author notesCheng-Yu Sun & Kai-Rong Lei These authors contributed equally to this work ... . AffiliationsDepartment of Medical Ultrasound, Shanghai Tenth People’s Hospital, Ultrasound Research and Education Institute, Tongji University School of Medicine, Shanghai 200072, ChinaCheng-Yu Sun, Bo-Ji Liu, Xiao-Wan Bo

Decreased deformability of lymphocytes in chronic lymphocytic leukemia

• PubMed • Google ScholarSearch for Yu Sun in:Nature Research journals • PubMed • Google Scholar Contributions Y.Z., Y.S. and C.W. designed the project. Y.Z. performed microfluidic experiemnts and processed ... resutls and constructed the manuscript. All authors reviewed the manuscript. Competing interests The authors declare no competing financial interests. Corresponding authors Correspondence to Chen Wang or Yu

Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis

The inflammasome adaptor protein, ASC, contributes to both innate immune responses and inflammatory diseases via self-oligomerization, which leads to the activation of the protease, caspase-1. Here, we report that the cytosolic tyrosine kinases, FAK and Pyk2, are differentially involved in NLRP3 and AIM2 inflammasome activation. The inhibition of FAK and Pyk2 with RNA...

Targeted next-generation sequencing reveals multiple deleterious variants in OPLL-associated genes

Ossification of the posterior longitudinal ligament of the spine (OPLL), which is characterized by ectopic bone formation in the spinal ligaments, can cause spinal-cord compression. To date, at least 11 susceptibility genes have been genetically linked to OPLL. In order to identify potential deleterious alleles in these OPLL-associated genes, we designed a capture array...

Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma

Gung University, Tao-Yuan, TaiwanShih-Jie Lin, Kun-Yi Chien, Yu-Tsun Lin, Yu-Sun Chang & Jau-Song YuMolecular Medicine Research Center, Chang Gung University, Tao-Yuan, TaiwanKai-Ping Chang, Jui-Shan Yi ... , Kun-Yi Chien, Lang-Ming Chi, Ying Liang, Yu-Sun Chang & Jau-Song YuDepartment of Medical Research, Chang Gung Memorial Hospital, Tao-Yuan, TaiwanLang-Ming ChiDepartment of Plastic & Reconstructive

ERβ localization influenced outcomes of EGFR-TKI treatment in NSCLC patients with EGFR mutations

. Xiaosheng Ding) and a pathologist (Yu Sun). Cell culture and chemicals. Human NSCLC cell lines (A549, HOP-62), HeLa cells, human bronchial epithelial cells (Beas/2b), mouse fibroblast cells (NIH-3T3) and

The optimal concentration of topical hydroxycamptothecin in preventing intraarticular scar adhesion

laboratory of Yangzhou University. Author information Author notesYuan Liang & Yu Sun These authors contributed equally to this work. AffiliationsDepartment of Orthopedics, Clinical Medical College of ... Yangzhou University, Subei People's Hospital, Nantong West Road 98, Yangzhou, 225001, ChinaYuan Liang, Yu Sun, Xiaolei Li, Lianqi Yan, Jingcheng Wang, Jinlong Hu, Huan Yu, Haixiang Xiao, Hui Chen, Zhongwei