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19 papers found.
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Increased 14-3-3β and γ protein isoform expressions in parasitic eosinophilic meningitis caused by Angiostrongylus cantonensis infection in mice

, Chuan-Min Yen. Data curation: Hung-Chin Tsai, Yu-Hsin Chen. Formal analysis: Susan Shin-Jung Lee. Funding acquisition: Hung-Chin Tsai. Investigation: Hung-Chin Tsai, Chuan-Min Yen, Susan Shin-Jung Lee ... . Methodology: Yu-Hsin Chen. Project administration: Hung-Chin Tsai, Susan Shin-Jung Lee, Yao-Shen Chen. Resources: Yao-Shen Chen. Supervision: Chuan-Min Yen, Yao-Shen Chen. Validation: Hung-Chin Tsai, Susan

Scheduling Patients’ Appointments: Allocation of Healthcare Service Using Simulation Optimization

In the service industry, scheduling medical procedures causes difficulties for both patients and management. Factors such as fluctuations in customer demand and service time affect the appointment scheduling systems’ performance in terms of, for example, patients’ waiting time, idle time of resources, and total cost/profits. This research implements four appointment scheduling...

Porcine induced pluripotent stem cell-derived osteoblast-like cells prevent glucocorticoid-induced bone loss in Lanyu pigs

Yang. Funding acquisition: Pin-Chi Tang, Lih-Ren Chen. Investigation: Yu-Jing Liao, Jenn-Rong Yang. Methodology: Yu-Jing Liao, Jenn-Rong Yang. Project administration: Yu-Jing Liao, Yu-Hsin Chen, Feng ... -Hsiang Chu, Ting-Chieh Kang, Jenn-Rong Yang. Resources: Pin-Chi Tang. Software: Yu-Hsin Chen, Feng-Hsiang Chu, Ting-Chieh Kang. Supervision: Jenn-Rong Yang. Validation: Lih-Ren Chen. Visualization

Scheduling Patients’ Appointments: Allocation of Healthcare Service Using Simulation Optimization

In the service industry, scheduling medical procedures causes difficulties for both patients and management. Factors such as fluctuations in customer demand and service time affect the appointment scheduling systems’ performance in terms of, for example, patients’ waiting time, idle time of resources, and total cost/profits. This research implements four appointment scheduling...

Renal Outcomes of Pioglitazone Compared with Acarbose in Diabetic Patients: A Randomized Controlled Study

Objective To assess the effect of pioglitazone on renal outcome, including urinary albumin excretion and estimated glomerular filtration rate (eGFR), in diabetic patients. Design A prospective, randomized, open-labeled, controlled study. Setting Taipei Veterans General Hospital. Patients Sixty type 2 diabetic patients treated with sulfonylureas and metformin, whose glycated...

Effects of glucose and blood pressure control on diabetic kidney disease in old patients with type 2 diabetes

Aims We determined the influence of age on the effects of glucose and blood pressure control on diabetic kidney disease in patients with type 2 diabetes. Methods A total of 721 patients with type 2 diabetes, aged 41–85 years and with an estimated glomerular filtration rate (eGFR) ≥30 mL/ [min · 1.73 m2], were enrolled in this study between August 2001 and December 2002. All...

Distal 10q trisomy with copy number gain in chromosome region 10q23.1–10q25.1: the Wnt signaling pathway is the most pertinent to the gene content in the region of copy number gain: a case report

Background Complete or partial trisomy 10q involves a duplication of 10q, or the long arm of chromosome 10. Distal 10q trisomy is a well-recognized and defined but rare genetic syndrome in which duplication of distal segments of 10q results in a pattern of malformations. Although abnormal chromosome phenotypes are commonly detected by visualization of chromosomes by traditional...

Emotional Context Influences Micro-Expression Recognition

Micro-expressions are often embedded in a flow of expressions including both neutral and other facial expressions. However, it remains unclear whether the types of facial expressions appearing before and after the micro-expression, i.e., the emotional context, influence micro-expression recognition. To address this question, the present study used a modified METT (Micro...

Distal 10q trisomy with copy number gain in chromosome region 10q23.1–10q25.1: the Wnt signaling pathway is the most pertinent to the gene content in the region of copy number gain: a case report

Complete or partial trisomy 10q involves a duplication of 10q, or the long arm of chromosome 10. Distal 10q trisomy is a well-recognized and defined but rare genetic syndrome in which duplication of distal segments of 10q results in a pattern of malformations. Although abnormal chromosome phenotypes are commonly detected by visualization of chromosomes by traditional cytogenetic...

Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase

Background Hepatocellular carcinoma (HCC) is a major cause of cancer deaths worldwide. However, current chemotherapeutic drugs for HCC are either poorly effective or expensive, and treatment with these drugs has not led to satisfactory outcomes. In a 2012 case report, we described our breakthrough finding in two advanced HCC patients, of whom one achieved complete remission of...

To Bind or Not to Bind? Different Temporal Binding Effects from Voluntary Pressing and Releasing Actions

Binding effect refers to the perceptual attraction between an action and an outcome leading to a subjective compression of time. Most studies investigating binding effects exclusively employ the “pressing” action without exploring other types of actions. The present study addresses this issue by introducing another action, releasing action or the voluntary lifting of the finger...

Amygdala Volume Predicts Inter-Individual Differences in Fearful Face Recognition

The present study investigates the relationship between inter-individual differences in fearful face recognition and amygdala volume. Thirty normal adults were recruited and each completed two identical facial expression recognition tests offline and two magnetic resonance imaging (MRI) scans. Linear regression indicated that the left amygdala volume negatively correlated with...

More Impact of Microalbuminuria on Retinopathy Than Moderately Reduced GFR Among Type 2 Diabetic Patients

OBJECTIVE The current study aimed to investigate whether microalbuminuria or moderately decreased glomerular filtration rate (GFR) is a better predictor for the development and progression of retinopathy in type 2 diabetic patients.

Thiazolidinediones and Risk of Long-Term Dialysis in Diabetic Patients with Advanced Chronic Kidney Disease: A Nationwide Cohort Study

Thiazolidinediones (TZDs) reduce urinary albumin excretion and proteinuria in diabetic nephropathy. The effect of TZDs on hard renal outcome in diabetic patients with chronic kidney disease (CKD) is unknown. We investigate the association of TZDs and risk of long-term dialysis or death in diabetic patients with advanced CKD. The nationwide population-based cohort study was...

CASME II: An Improved Spontaneous Micro-Expression Database and the Baseline Evaluation

A robust automatic micro-expression recognition system would have broad applications in national safety, police interrogation, and clinical diagnosis. Developing such a system requires high quality databases with sufficient training samples which are currently not available. We reviewed the previously developed micro-expression databases and built an improved one (CASME II), with...

Chitosan Modification of Adenovirus to Modify Transfection Efficiency in Bovine Corneal Epithelial Cells

Background The purpose of this study is to modulate the transfection efficiency of adenovirus (Ad) on the cornea by the covalent attachment of chitosan on adenoviral capsids via a thioether linkage between chitosan modified with 2-iminothiolane and Ad cross-linked with N-[γ-maleimidobutyryloxy]succinimide ester (GMBS). Methodology/Principal Findings Modified Ad was obtained by...

Use of Arsenic-Induced Palmoplantar Hyperkeratosis and Skin Cancers to Predict Risk of Subsequent Internal Malignancy

Ling-I Hsu ) Gwo-Shing Chen Chih-Hung Lee Tse-Yen Yang Yu-Hsin Chen Yuan-Hung Wang Yu-Mei Hsueh Hung-Yi Chiou Meei-Maan Wu Chien-Jen Chen American Journal of Epidemiology The Author 2013. Published ... exposure to any other lung carcinogen. ACKNOWLEDGMENTS Author affiliations: Genomics Research Center, Acade mia Sinica, Taipei, Taiwan (Ling-I Hsu, Tse-Yen Tang, Yu-Hsin Chen, Meei-Maan Wu, Chien-Jen Chen

Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan

Background Arsenic exposure is an important public health issue worldwide. Dose-response relationship between arsenic exposure and risk of urothelial carcinoma (UC) is consistently observed. Inorganic arsenic is methylated to form the metabolites monomethylarsonic acid and dimethylarsinic acid while ingested. Variations in capacity of xenobiotic detoxification and arsenic...

Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan

Arsenic exposure is an important public health issue worldwide. Dose-response relationship between arsenic exposure and risk of urothelial carcinoma (UC) is consistently observed. Inorganic arsenic is methylated to form the metabolites monomethylarsonic acid and dimethylarsinic acid while ingested. Variations in capacity of xenobiotic detoxification and arsenic methylation might...