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Search: authors:"Yuhang Zhang"

8 papers found.
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Divide and conquer: two stem cell populations in squamous epithelia, reserves and the active duty forces

Stem cells are of great interest to the scientific community due to their potential role in regenerative and rejuvenative medicine. However, their role in the aging process and carcinogenesis remains unclear. Because DNA replication in stem cells may contribute to the background mutation rate and thereby to cancer, reducing proliferation and establishing a relatively quiescent...

CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p

Activation of CXCL12/CXCR4 axis has been found to be associated with invasion and metastasis in many cancers. However, the underlying mechanism remains elusive. Increasing data highlight that non-coding RNAs are linked to CRC progression. The effects of CXCR4 were investigated using villin-CXCR4 transgenic mice model by flow cytometry assay, immunohistochemistry, and Western blot...

Influences of anthropogenic land use on microbial community structure and functional potentials of stream benthic biofilms

Stream ecosystems are the primary receivers of nutrient and organic carbon exported from terrestrial ecosystems and are profoundly influenced by the land use of the surrounding landscape. The aquatic impacts of anthropogenic land use are often first observed in stream benthic biofilms. We studied the benthic biofilms in streams flowing through forest (upstream) and anthropogenic...

Identifying novel fruit-related genes in Arabidopsis thaliana based on the random walk with restart algorithm

Fruit is essential for plant reproduction and is responsible for protection and dispersal of seeds. The development and maturation of fruit is tightly regulated by numerous genetic factors that respond to environmental and internal stimulation. In this study, we attempted to identify novel fruit-related genes in a model organism, Arabidopsis thaliana, using a computational method...

CXCL12/CXCR4 axis induced miR-125b promotes invasion and confers 5-fluorouracil resistance through enhancing autophagy in colorectal cancer

The activation of CXCL12/CXCR4 axis is associated with potential progression of cancer, such as invasion, metastasis and chemoresistance. However, the underlying mechanisms of CXCL12/CXCR4 axis and cancer progression have been poorly explored. We hypothesized that miRNAs might be critical downstream mediators of CXCL12/CXCR4 axis involved in cancer invasion and chemoresistance in...

Activation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth

The hair follicle dermal papilla (DP) contains a unique prominin-1/CD133-positive (CD133+) cell subpopulation, which has been shown to possess hair follicle-inducing capability. By assaying for endogenous CD133 expression and performing lineage tracing using CD133-CreERT2; ZsGreen1 reporter mice, we find that CD133 is expressed in a subpopulation of DP cells during the growth...

Anthropogenically enhanced chemical weathering and carbon evasion in the Yangtze Basin

Research journals • PubMed • Google ScholarSearch for Rolf David Vogt in:Nature Research journals • PubMed • Google ScholarSearch for Yuhang Zhang in:Nature Research journals • PubMed • Google ScholarSearch

Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate

Yuhang Zhang Thomas Andl Steven H. Yang Monica Teta Fei Liu John T. Seykora John W. Tobias Stefano Piccolo Ruth Schmidt-Ullrich Andras Nagy Makoto M. Taketo Andrzej A. Dlugosz Sarah E. Millar