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32 papers found.
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Function, clinical application, and strategies of Pre-mRNA splicing in cancer

, Qianjing Zhang, Yuhong Chen, Yupei Wang, Xuetian Zhang, Yang Liu, Chao Sun & Hong ZhangKey Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, 730000, Lanzhou, ChinaCuixia ... Di, Qianjing Zhang, Yuhong Chen, Yupei Wang, Xuetian Zhang, Yang Liu, Chao Sun & Hong ZhangCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, ChinaCuixia Di, Qianjing Zhang

The cost calculation method of construction 3D printing aligned with internet of things

Yuhong Chen 1 Yijia Li 0 0 School of Management, Tianjin University of Technology , Binshuixi Road, Xiqing District, Tianjin 300384 , China 1 School of Design & Environment, National University of

Ordering Strategy Analysis of Prefabricated Component Manufacturer in Construction Supply Chain

Firstly, the characteristics and present situations of the prefabricated construction supply chain are analyzed; inventory cost models for construction material of every phase order, one-off order, and fractionated order are built based on traditional EOQ model and construction supply chain theory. Next, the order decision is represented in binary numbers 0 and 1, in which 0...

Ordering Strategy Analysis of Prefabricated Component Manufacturer in Construction Supply Chain

Firstly, the characteristics and present situations of the prefabricated construction supply chain are analyzed; inventory cost models for construction material of every phase order, one-off order, and fractionated order are built based on traditional EOQ model and construction supply chain theory. Next, the order decision is represented in binary numbers 0 and 1, in which 0...

Genome-wide analysis identified 17 new loci influencing intraocular pressure in Chinese population

Intraocular pressure (IOP) is a major risk factor for glaucoma. Genetic determinants of intraocular pressure can provide critical insights into the genetic architecture of glaucoma and, as a result, open new avenues for therapeutic intervention. We performed a genome-wide association study and replication analysis of 8,552 Chinese participants. In the genome-wide association...

Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress

paper. Authors? Contributions Yuhong Chen and Sheng Jin contributed equally to this work. Acknowledgments This study was supported by the National Natural Science Foundation of China (Grant nos

Differences between fellow eyes of acute and chronic primary angle closure (glaucoma): An ultrasound biomicroscopy quantitative study

Data curation: Mengwei Li, Yuhong Chen, Xiaoxiao Chen, Wenqing Zhu, Xueli Chen, Xiaolei Wang, Yuan Fang, Xiangmei Kong, Yi Dai, Junyi Chen. Funding acquisition: Xinghuai Sun. Investigation: Mengwei Li ... , Yuhong Chen. Project administration: Mengwei Li. Validation: Xinghuai Sun. Writing ± original draft: Mengwei Li. Writing ± review & editing: Yuhong Chen, Xinghuai Sun. 13 / 14 1. Foster PJ , Johnson

Changes in Corneal Biomechanical Properties after Long-Term Topical Prostaglandin Therapy

Objective To compare corneal biomechanical properties, measured by a newly developed tonometer (Corneal Visualization Scheimpflug Technology, Corvis ST), in untreated primary open angle glaucoma (POAG) patients, POAG patients with long-term topical prostaglandin analog (PGA) therapy and in normal controls. Further is to investigate the potential effects of PGA on corneal...

Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma

Shorter axial length observed in patients with primary angle closure glaucoma (PACG) might be due to altered matrix metalloproteinase-9 (MMP9) activity resulting in ECM remodeling during eye growth and development. This study aimed to evaluate common variants in MMP9 for association with PACG. Six tag SNPs of MMP9 were genotyped in a Chinese sample of 1,030 cases, including 572...

Thyroid hormones associate with risk of incident chronic kidney disease and rapid decline in renal function: a prospective investigation

Background Thyroid hormones have been associated with renal dysfunction in cross-sectional studies. However, prospective studies exploring the effect of thyroid hormones on renal function decline were sparse and got contradictive results. We aimed to prospectively explore the associations of thyroid hormones with incident chronic kidney disease (CKD) and rapid decline in...

Thyroid hormones associate with risk of incident chronic kidney disease and rapid decline in renal function: a prospective investigation

Background Thyroid hormones have been associated with renal dysfunction in cross-sectional studies. However, prospective studies exploring the effect of thyroid hormones on renal function decline were sparse and got contradictive results. We aimed to prospectively explore the associations of thyroid hormones with incident chronic kidney disease (CKD) and rapid decline in...

Evaluation of Genetic Diversity and Development of a Core Collection of Wild Rice (Oryza rufipogon Griff.) Populations in China

Common wild rice (Oryza rufipogon Griff.), the progenitor of Asian cultivated rice (O. sativa L.), is endangered due to habitat loss. The objectives of this research were to evaluate the genetic diversity of wild rice species in isolated populations and to develop a core collection of representative genotypes for ex situ conservation. We collected 885 wild rice accessions from...

Improved clinical outcomes of rhG-CSF-mobilized blood and marrow haploidentical transplantation compared to propensity score-matched rhG-CSF-primed peripheral blood stem cell haploidentical transplantation: a multicenter study

The effects of haploidentical rhG-CSF-mobilized blood and marrow transplantation (HBMT) on hematological malignances are well established. Previous prospective single-center studies have demonstrated better survival after HBMT versus haploidentical rhG-CSF-mobilized peripheral blood stem cell transplantation (HPBSCT) for acute leukemia (AL) not in remission (NR) or in more than...

R-Ras Regulates Murine T Cell Migration and Intercellular Adhesion Molecule-1 Binding

The trafficking of T-lymphocytes to peripheral draining lymph nodes is crucial for mounting an adaptive immune response. The role of chemokines in the activation of integrins via Ras-related small GTPases has been well established. R-Ras is a member of the Ras-subfamily of small guanosine-5’-triphosphate-binding proteins and its role in T cell trafficking has been investigated in...

Effects of drought and salt-stresses on gene expression in Caragana korshinskii seedlings revealed by RNA-seq

Background Drought and soil salinity are major abiotic stresses. The mechanisms of stress tolerance have been studied extensively in model plants. Caragana korshinskii is characterized by high drought and salt tolerance in northwestern China; unique patterns of gene expression allow it to tolerate the stress imposed by dehydration and semi-desert saline soil. There have, however...

Evaluation of upper limb muscle fatigue based on surface electromyography

Fatigue is believed to be a major contributory factor to occupational injuries in machine operators. The development of accurate and usable techniques to measure operator fatigue is therefore important. In this study, we used a novel method based on surface electromyography (sEMG) of the biceps brachii and the Borg scale to evaluate local muscle fatigue in the upper limb after...

The Crystal Structure of Arabidopsis VSP1 Reveals the Plant Class C-Like Phosphatase Structure of the DDDD Superfamily of Phosphohydrolases

Arabidopsis thaliana vegetative storage proteins, VSP1 and VSP2, are acid phosphatases and belong to the haloacid dehalogenase (HAD) superfamily. In addition to their potential nutrient storage function, they were thought to be involved in plant defense and flower development. To gain insights into the architecture of the protein and obtain clues about its function, we have...

Association between carotid intima-media thickness and index of central fat distribution in middle-aged and elderly Chinese

Background Evidence has demonstrated that central fat distribution produces the most profound metabolic abnormalities and is associated with an increased risk of atherosclerotic cardiovascular diseases. We aimed to investigate whether the indexes of central fat distribution, including waist-to-height ratio (WHtR) and visceral fat area (VFA), were stronger risk factors of...

Gender difference in carotid intima-media thickness in type 2 diabetic patients: a 4-year follow-up study

BackgroundDifferent population studies have reported gender difference in carotid intima-media thickness (CIMT), which is proved to be a risk factor of cardiovascular diseases. However, few longitudinal researches examine this gender difference in type 2 diabetes mellitus (T2DM) patients. Therefore, we prospectively analyzed CIMT in T2DM patients over a 4-year follow-up period...

Low-Grade Albuminuria Is Associated with Metabolic Syndrome and Its Components in Middle-Aged and Elderly Chinese Population

Background Micro-albuminuria has been well established as one of the risk factors of metabolic syndrome (MetS). However, the association of MetS and its components with low-grade albuminuria among those with normal urinary albumin excretion has not been clearly elucidated in Chinese population. Methodology and Findings A cross-sectional study was conducted among 9,579...