Advanced search    

Search: authors:"Yuko Ohno"

12 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Impact of fatty pancreas and lifestyle on the development of subclinical chronic pancreatitis in healthy people undergoing a medical checkup

BackgroundAlthough fat accumulation in human organs is associated with a variety of diseases, there is little evidence about the effect of a fatty pancreas on the development of subclinical chronic pancreatitis over the clinical course.MethodsWe conducted a prospective cohort study from 2008 to 2014 of patients who underwent a medical checkup consultation for fat accumulated in...

The effect of concentric constriction of the visual field to 10 and 15 degrees on simulated motor vehicle accidents

Udagawa, Shinji Ohkubo, Aiko Iwase, Yuto Susuki, Yuko Ohno. Methodology: Sachiko Udagawa, Aiko Iwase. Project administration: Aiko Iwase. Resources: Aiko Iwase, Kazuhisa Sugiyama. Software: Hiroshi Ono ... & editing: Shiho Kunimatsu-Sanuki, Takeo Fukuchi, Chota Matsumoto, Yuko Ohno, Kazuhisa Sugiyama, Makoto Araie. 11 / 13 12 / 13 1. Szlyk JP , Mahler CL , Seiple W , Edward DP , Wilensky JT. Driving

Acentric chromosome ends are prone to fusion with functional chromosome ends through a homology-directed rearrangement

The centromeres of many eukaryotic chromosomes are established epigenetically on potentially variable tandem repeats; hence, these chromosomes are at risk of being acentric. We reported previously that artificially created acentric chromosomes in the fission yeast Schizosaccharomyces pombe can be rescued by end-to-end fusion with functional chromosomes. Here, we show that most...

Prognostic significance of endothelial dysfunction in patients undergoing percutaneous coronary intervention in the era of drug-eluting stents

Background Endothelial function is a prognostic predictor in patients undergoing percutaneous coronary intervention (PCI). However, in an era with widespread use of drug-eluting stents, the clinical relevance of endothelial dysfunction on restenosis in patients undergoing PCI has not been fully evaluated. Methods This study included 80 patients with stable angina pectoris. Flow...

The change in lifestyle data during 9 years: the reliability and continuity of baseline health practices

ObjectivesTo reveal change patterns in self-reported lifestyle data for 9 years, and examine the characteristics of changes by type of lifestyle and ageing.MethodsThe authors used the lifestyle data of 7,080 male workers aged 20–59 who received checkups for 9 years. The proportions of change patterns during the 9 years were determined in seven health practices; smoking, eating...

Increase in Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) Had a Strong Impact on the Development of Type 2 Diabetes in Japanese Individuals with Impaired Insulin Secretion: The Saku Study

Our aim was to assess the impact of increase in homeostasis model assessment of insulin resistance (HOMA-IR) on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion (IIS). This study included 2,209 participants aged 30–69 without diabetes at baseline who underwent comprehensive medical check-ups between April 2006 and March 2007 at Saku...

Impact of impaired insulin secretion and insulin resistance on the incidence of type 2 diabetes mellitus in a Japanese population: the Saku study

Aims/hypothesis To assess the impact of impaired insulin secretion (IIS) and insulin resistance (IR) on type 2 diabetes incidence in a Japanese population. Methods This 4 year cohort study included 3,059 participants aged 30–69 without diabetes at baseline who underwent comprehensive medical check-ups between April 2006 and March 2007 at Saku Central Hospital. Based on their...

Bezafibrate improves postprandial hypertriglyceridemia and associated endothelial dysfunction in patients with metabolic syndrome: a randomized crossover study

Background Postprandial elevation of triglyceride-rich lipoproteins impairs endothelial function, which can initiate atherosclerosis. We investigated the effects of bezafibrate on postprandial endothelial dysfunction and lipid profiles in patients with metabolic syndrome. Methods Ten patients with metabolic syndrome were treated with 400 mg/day bezafibrate or untreated for 4...

Practical application of cure mixture model for long-term censored survivor data from a withdrawal clinical trial of patients with major depressive disorder

Ichiro Arano Tomoyuki Sugimoto 0 Toshimitsu Hamasaki 0 Yuko Ohno 0 Department of Biomedical Statistics, Osaka University Graduate School of Medicine , Yamadaoka 2-2, Suita 567-0871, Osaka , Japan ... Tomoyuki Sugimoto and Yuko Ohno declare no competing interests. Ichiro Arano is an employee of Pfizer Japan, and Toshimitsu Hamasaki was an employee of Pfizer Japan between 1997 and 2004. Authors

Long-term effects of lifestyle on multiple risk factors in male workers

Objectives To examine the long-term effects of lifestyle on the recovery from risk factors of cardiovascular disease and to discuss the difference in the effects of lifestyle modification in subjects with a single risk factor and those with multiple risk factors. Methods We used checkup data compiled for 6477 male workers, aged 20–59 years in 1995, with risk factors of...

Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non- diabetic subjects: a preliminary report

Background Postprandial hyperlipidemia impairs endothelial function and participates in the development of atherosclerosis. We investigated the postprandial effects of a dipeptidyl peptidase IV inhibitor, alogliptin, on endothelial dysfunction and the lipid profile. Methods A randomized cross-over trial design in 10 healthy volunteers (8 males and 2 females, 35 ± 10 years) was...