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ADAR1 silencing-induced HUVEC apoptosis is mediated by FGFR2 under hypoxia stress

ADAR1 silencing-induced HUVEC apoptosis is mediated by FGFR2 under hypoxia stress Yun Jiang,1 Zhancheng Wang,1 Xu Chen,1 Wei Wang,1 Xiaowei Wang2 1Department of Cardiology, The Eighth People’s

A new insight into the phase transition in the early Universe with two Higgs doublets

Abstract We study the electroweak phase transition in the alignment limit of the CP-conserving two-Higgs-doublet model (2HDM) of Type I and Type II. The effective potential is evaluated at one-loop, where the thermal potential includes Daisy corrections and is reliably approximated by means of a sum of Bessel functions. Both 1-stage and 2-stage electroweak phase transitions are...

Molecular markers and cytogenetics to characterize a wheat-Dasypyrum villosum 3V (3D) substitution line conferring resistance to stripe rust

. Formal analysis: Yun Jiang, Ying Wang. Funding acquisition: Jie Zhang, Yuanlin Guo, Hai Long. 11 / 14 Investigation: Jie Zhang, Ying Wang, Guangbing Deng. Supervision: Pu Xuan. Validation: Hai Long

The SMEFTsim package, theory and tools

We report codes for the Standard Model Effective Field Theory (SMEFT) in FeynRules — the SMEFTsim package. The codes enable theoretical predictions for dimension six operator corrections to the Standard Model using numerical tools, where predictions can be made based on either the electroweak input parameter set \( \left\{{\widehat{\alpha}}_{ew},{\widehat{m}}_Z,{\widehat{G}}_F...

Human iPSC-MSCs prevent steroid-resistant neutrophilic airway inflammation via modulating Th17 phenotypes

BackgroundHuman induced pluripotent stem cells-derived mesenchymal stem cells (iPSC-MSCs) have been shown to be effective in Type 2 helper T cells (Th2)-dominant eosinophilic allergic airway inflammation. However, the role of iPSC-MSCs in Type 17 helper T cells (Th17)-dominant neutrophilic airway inflammation remains poorly studied. Therefore, this study was to explore the...

Quality-Aware Incentive Mechanism for Mobile Crowd Sensing

Received 4 March 2017; Revised 24 July 2017; Accepted 22 August 2017; Published 28 September 2017 Academic Editor: Javier Sedano Copyright © 2017 Ling-Yun Jiang et al. This is an open access article

Insect-bacteria parallel evolution in multiple-co-obligate-aphid association: a case in Lachninae (Hemiptera: Aphididae)

, ChinaRui Chen, Jing Chen, Li-Yun Jiang & Ge-Xia QiaoInstitute of Plant Protection, Liaoning Academy of Agricultural Sciences, Shenyang, 110161, ChinaZhe WangCollege of Life Sciences, University of Chinese ... Scholar Search for Jing Chen in:Nature Research journals • PubMed • Google Scholar Search for Li-Yun Jiang in:Nature Research journals • PubMed • Google Scholar Search for Ge-Xia Qiao in:Nature Research

SlPIN1 regulates auxin efflux to affect flower abscission process

Solanum lycopersicum PIN-FORMED1 (SlPIN1), a major auxin efflux facilitator, contributes to the establishment of auxin maxima during organ initiation and development in tomato. However, the functions of SlPIN1 during organ abscission remain unclear. In our study, SlPIN1 expression decreased immediately after flower removal and increased following IAA treatment, indicating a high...

Bufalin suppresses hepatocarcinogenesis by targeting β-catenin/TCF signaling via cell cycle-related kinase

Hepatocellular carcinoma (HCC) is one of the most aggressive malignant tumors, of which treatment options are limited especially in advanced stage. Bufalin, the major digoxin-like component of the traditional Chinese medicine Chansu, exhibits significant antitumor activities in hepatoma cells, but the potential mechanism is obscure. Cell cycle-related kinase (CCRK) is recently...

Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs

. Kun Chen, Wenjia Sun, Yun Jiang, Jie Sun, and Beidong Chen performed the experiments. Wenjia Sun, Huan Gong, and Yanyang Zhao analyzed the data. Ruomei Qi wrote the paper. Kun Chen, Wenjia Sun, and Yun ... Jiang contributed equally to this work. Acknowledgments This work was supported by the grants from the National Natural Science Foundation of China (Grant nos. 80471051, 81270379, 81070231, and 91649110

Higgs dark matter from a warped extra dimension — the truncated-inert-doublet model

AbstractWe construct a 5D \( {\mathrm{\mathbb{Z}}}_2 \)-symmetric model with three D3-branes: two IR ones with negative tension located at the ends of an extra-dimensional interval and a UV-brane with positive tension placed in the middle of the interval — IR-UV-IR model. The background solutions for this geometric setup are found without and with taking into account the...

Two novel BMP-2 variants identified in patients with thoracic ossification of the ligamentum flavum

Yan Zeng Weishi Li Zhaoqing Guo Qiang Qi Woquan Zhong Yun Jiang Thoracic ossification of the ligamentum flavum (TOLF) is a common cause of thoracic spinal canal stenosis and has been reported almost

Wheat straw biochar-supported nanoscale zerovalent iron for removal of trichloroethylene from groundwater

This study synthesized the wheat straw biochar-supported nanoscale zerovalent iron (BC-nZVI) via in-situ reduction with NaBH4 and biochar pyrolyzed at 600°C. Wheat straw biochar, as a carrier, significantly enhanced the removal of trichloroethylene (TCE) by nZVI. The pseudo-first-order rate constant of TCE removal by BC-nZVI (1.079 h−1) within 260 min was 1.4 times higher and 539...

Mechanism of Calcium Fluoride Acceleration for Vacuum Carbothermic Reduction of Magnesia

The use of a small amount of calcium fluoride as an additive greatly accelerated the reduction of magnesia during the preparation of magnesium from magnesia using the vacuum carbothermic reduction method. At 1573 K (1300 °C), the magnesia reaction rates of the samples with 1, 3, and 5 pct CaF2 were all approximately 26 pct, three times that of free CaF2, and they were arranged in...

Transcriptome Analysis of Blunt Snout Bream (Megalobrama amblycephala) Reveals Putative Differential Expression Genes Related to Growth and Hypoxia

The blunt snout bream (Megalobrama amblycephala) is an important freshwater aquaculture species, but it is sensitive to hypoxia. No transcriptome data related to growth and hypoxia response are available for this species. In this study, we performed de novo transcriptome sequencing for the liver and gills of the fast-growth family and slow-growth family derived from ‘Pujiang No.1...

Relationship between Gingival Inflammation and Pregnancy

An increase in the prevalence and severity of gingival inflammation during pregnancy has been reported since the 1960s. Though the etiology is not fully known, it is believed that increasing plasma sex steroid hormone levels during pregnancy have a dramatic effect on the periodontium. Current works of research have shown that estrogen and progesterone increasing during pregnancy...

Sex Hormones Enhance Gingival Inflammation without Affecting IL-1β and TNF-α in Periodontally Healthy Women during Pregnancy

Hormones (progesterone and estradiol) change greatly during pregnancy; however, the mechanism of hormonal changes on gingival inflammation is still unclear. This study is to evaluate the effects of hormonal changes during pregnancy on gingival inflammation and interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in gingival crevicular fluid (GCF). 30 periodontally healthy...

Is the subfamily Eriosomatinae (Hemiptera: Aphididae) monophyletic?

Eriosomatinae, the gall-forming aphid subfamily, traditionally consists of 3 tribes, Eriosomatini, Pemphigini, and Fordini. However, the phylogenetic relationships among these tribes remain controversial, which has made it difficult to conduct further investigation regarding the evolution of galls and host alternations in this group. We analyzed the molecular phylogeny of the...

Resistin Induces Hypertension and Insulin Resistance in Mice via a TLR4-Dependent Pathway

Third Hospital of Wuhan, Wuhan, ChinaYoutao Hu AuthorsSearch for Yun Jiang in:Nature Research journals • PubMed • Google ScholarSearch for Linfang Lu in:Nature Research journals • PubMed • Google