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38 papers found.
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FBS framework application based on user requirement analysis

Users’ requirements are key factor for optimizing the design of products. It could be classified into two groups: qualitative research work and quantitative research work. Wireless internet terminal equipment could be used as one example to further study the qualitative research work of requirements. FBS guided by users’ requirements was discussed. The users centered service...

Cell-to-cell variability and robustness in S-phase duration from genome replication kinetics

Genome replication, a key process for a cell, relies on stochastic initiation by replication origins, causing a variability of replication timing from cell to cell. While stochastic models of eukaryotic replication are widely available, the link between the key parameters and overall replication timing has not been addressed systematically. We use a combined analytical and...

Embedded acoustic emission system based on rock sound source crowd location

Rock acoustic emission is often used to study the evolution of brittle materials. The cause of rock internal damage can be monitored continuously and real-timely by sensing rock acoustic wave. However, the key problem is how to split the position and analyze the acoustic emission characteristics based on the acoustic tracking experiment. First, we collected the acoustic waves of...

Effects of cooperation between translating ribosome and RNA polymerase on termination efficiency of the Rho-independent terminator

An experimental system was designed to measure in vivo termination efficiency (TE) of the Rho-independent terminator and position–function relations were quantified for the terminator tR2 in Escherichia coli. The terminator function was almost completely repressed when tR2 was located several base pairs downstream from the gene, and TE gradually increased to maximum values with...

Identification and Characterization of the Major Chemical Constituents in Fructus Akebiae by High-Performance Liquid Chromatography Coupled with Electrospray Ionization-Quadrupole-Time-of-Flight Mass Spectrometry

Fructus Akebiae (FA), the dry fruit of Akebia quinata (THUNB.) DECNE., possesses potent antidepressant properties. Owing to the structural complexity, high polarity and thermal lability in plants, it is difficult and time-consuming to analyze the major chemical constituents by traditional strategies that involve extraction, isolation, purification and identification by chemical...

The Partitioned Mixed Model of Finite Element Method and Interface Stress Element Method with Arbitrary Shape of Discrete Block Element

; Accepted 18 September 2013 Academic Editor: Zhiqiang Hu Copyright © 2013 Zhang Qing et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

An indel polymorphism within pre-miR3131 confers risk for hepatocellular carcinoma

Polymorphisms in pre-miRNAs may affect its expression, then have effect on its target mRNAs and be associated with cancer susceptibility. In this study, we evaluated the association of an indel polymorphism rs57408770 in pre-miR-3131 with hepatocellular carcinoma (HCC) susceptibility in a Chinese population. The contribution of rs57408770 to HCC risk was investigated in two...

Study on the Macromesoscopic Yield Criterion of Concrete Material

In mesoscopy, the concrete material is a kind of composite consisting of mortar matrix, aggregate, and the interface between them. And the shape of aggregate is assumed to be spherical and the mortar matrix is supposed to satisfy the Drucker-Prager yield criterion. The energy density support function is introduced to reflect the yield surface of mortar matrix. In order to solve...

Study on the Macromesoscopic Yield Criterion of Concrete Material

In mesoscopy, the concrete material is a kind of composite consisting of mortar matrix, aggregate, and the interface between them. And the shape of aggregate is assumed to be spherical and the mortar matrix is supposed to satisfy the Drucker-Prager yield criterion. The energy density support function is introduced to reflect the yield surface of mortar matrix. In order to solve...

Outcomes of catheter ablation of atrial fibrillation in patients with hypertrophic cardiomyopathy: a systematic review and meta-analysis

Over the past decade, catheter ablation (CA) has become an established therapy for symptomatic atrial fibrillation (AF). Atrial fibrillation is common in hypertrophic cardiomyopathy (HCM) patients, and restoring sinus rhythm is of great clinical benefit to them. Therefore, we conducted a systematic review and meta-analysis of the available data to evaluate the effectiveness and...

Deterioration of left ventricular systolic function in extended Pacing to Avoid Cardiac Enlargement (PACE) trial: the predictive value of early systolic dyssynchrony

Biventricular (BiV) pacing was superior to right ventricular apical (RVA) pacing at extended follow-up in the Pacing to Avoid Cardiac Enlargement (PACE) trial. Early pacing-induced systolic dyssynchrony (DYS) might be related to mid-term result. However, it remains unknown whether early pacing-induced DYS can predict long-term reduction of left ventricular (LV) systolic function.

Association between indel polymorphism in the promoter region of lncRNA GAS5 and the risk of hepatocellular carcinoma

The growth arrest special 5 (GAS5) is known to be involved in various cancers. However, its expression regulation remains unclear. Polymorphisms in the promoter region of GAS5 may affect its expression and be associated with cancer susceptibility. In this research, we first evaluated the association of a 5-base pair indel polymorphism (rs145204276) in the promoter region of GAS5...

Blood Neutrophil to Lymphocyte Ratio as a Predictor of Hypertension

Hypertension is a significant global public health challenge. Low-grade inflammation is known to facilitate the development of essential hypertension and target-organ hypertensive damage. Neutrophil to lymphocyte ratio (NLR) is a simple and reliable indicator of inflammation that may also be useful in the prediction of hypertension.

Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/β-catenin signaling pathway in human lung cancer

Desmosomes are intercellular junctions that confer strong cell–cell adhesion, thus conferring resistance against mechanical stress on epithelial tissues. A body of evidence indicates that decreased expression of desmosomal proteins is associated with poor prognosis in various cancers. As a key component of desmosomal plaque proteins, the functional role of desmoplakin (DSP) in...

Approaching regional left atrial function by tissue Doppler velocity and strain imaging

Atrial function is an integral part for the proper performance of the circulatory system. Assessment of its haemodynamic and mechanical characteristics by use of non-invasive echocardiography, including tissue Doppler velocity and strain imaging, may provide a better insight into atrial function and its relationship with ventricular function. From an electromechanical perspective...

Five Serum Proteins Identified Using SELDI-TOF-MS as Potential Biomarkers of Gastric Cancer

The aims of this study were to detect serum proteomic patterns in gastric cancer serum samples using Surface-enhanced Laser Desorption/ionization-Time-of-flight-Mass Spectrometry ProteinChip array technology, to screen biomarker candidates, to build diagnostic models and to evaluate their clinical significance.