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6 papers found.
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Involvement of DDAH/ADMA/NOS/cGMP and COX-2/PTGIS/cAMP Pathways in Human Tissue Kallikrein 1 Protecting Erectile Function in Aged Rats

Our previous studies had reported that Human Tissue Kallikrein 1 (hKLK1) preserved erectile function in aged transgenic rats, while the detailed mechanism of hKLK1 protecting erectile function in aged rats through activation of cGMP and cAMP was not mentioned. To explore the latent mechanism, male wild-type Sprague-Dawley rats (WTR) and transgenic rats harboring the hKLK1 gene...

Epidemiological Characteristics of Hypertension in the Elderly in Beijing, China

Background/Objectives The prevalence rate of hypertension increases significantly with the aging society, and hypertension is obviously becoming a major health care concern in China. The aim of the study was to explore the epidemiological characteristics of hypertension in the elderly and to provide a basis for the prevention of hypertension. Design 3-cross sectional studies in...

A competing-risk-based score for predicting twenty-year risk of incident diabetes: the Beijing Longitudinal Study of Ageing study

Jin Guo Lixin Tao Gehendra Mahara KunYang Jie Zhang Sijia Tian Haibin Li Kuo Liu Yanxia Luo Feng Zhang Zhe Tang Xiuhua Guo OPEN Few risk tools have been proposed to quantify the long-term risk of

The Trajectories and Correlation between Physical Limitation and Depression in Elderly Residents of Beijing, 1992–2009

Background Physical limitation and psychological distress have been reported to be related, but studies describing the change of instrumental activities of daily living (IADLs) and depression syndrome over time or exploring the link pattern for their development are limited. The study was to assess distinctive patterns for the development of physical limitation and depression and...

Risk Factors for Cerebrovascular Disease Mortality among the Elderly in Beijing: A Competing Risk Analysis

Objective To examine the associations of combined lifestyle factors and physical conditions with cerebrovascular diseases (CBVD) mortality, after accounting for competing risk events, including death from cardiovascular diseases, cancers and other diseases. Methods Data on 2010 subjects aged over 55 years were finally analyzed using competing risk models. All the subjects were...

Analysis of frailty and survival from late middle age in the Beijing Longitudinal Study of Aging

Background Frailty in individuals can be operationalized as the accumulation of health deficits, for which several trends have been observed in Western countries. Less is known about deficit accumulation in China, the country with the world's largest number of older adults. Methods This study analyzed data from the Beijing Longitudinal Study of Aging, to evaluate the relationship...