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An Experimental Investigation on Flexural Behavior of Reinforced Concrete Beams Strengthened by an Intelligent CFRP Plate with Built-In Optical Fiber Bragg Grating Sensors

2017; Accepted 31 December 2017; Published 16 July 2018 Academic Editor: Carlos Ruiz Copyright © 2018 Zhi Zhou and Zhenzhen Wang. This is an open access article distributed under the Creative Commons

Establishment of a new genus, Brephallus Wang et al., gen. nov. (Blattodea, Blaberidae, Epilamprinae) based on two species from Pseudophoraspis, with details of polymorphism in species of Pseudophoraspis

dimorphism; species delimitation; taxonomy; cockroaches - Copyright Zhenzhen Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0

MiR-99b-5p and miR-203a-3p Function as Tumor Suppressors by Targeting IGF-1R in Gastric Cancer

, Xi'an, Shaanxi , P. R. China. Zhenzhen Wang and Zhenghao MicroRNAs (miRNAs) have been explored in many critical cellular processes, including proliferation and apoptosis. The purpose of this study was to ... Zhenzhen Wang and Zhenghao Zhao involved in study designation, experimental operation, data analysis and drafting the manuscript. Yang Yang involved in sample collection, analysis and interpretation of data

Fiber-Reinforced Polymer-Packaged Optical Fiber Bragg Grating Strain Sensors for Infrastructures under Harsh Environment

Optical fiber Bragg grating (FBG) has been recognized as an outstanding high-performance local monitoring sensor and is largely applied in structural health monitoring (SHM). This paper proposes a series of fiber-reinforced polymer- (FRP-) packaged optical fiber Bragg grating strain sensors to completely meet the requirements of rough civil engineering infrastructures, and their...

Enhanced disease resistance and drought tolerance in transgenic rice plants overexpressing protein elicitors from Magnaporthe oryzae

Exogenous application of the protein elicitors MoHrip1 and MoHrip2, which were isolated from the pathogenic fungus Magnaporthe oryzae (M. oryzae), was previously shown to induce a hypersensitive response in tobacco and to enhance resistance to rice blast. In this work, we successfully transformed rice with the mohrip1 and mohrip2 genes separately. The MoHrip1 and MoHrip2...

The speed of tubule formation of two fijiviruses corresponds with their dissemination efficiency in their insect vectors

Background Rice black-streaked dwarf virus (RBSDV) and Southern rice black-streaked dwarf virus (SRBSDV) are two closely related fijiviruses transmitted by the small brown planthopper (SBPH) and white-backed planthopper (WBPH), respectively. SRBSDV has a latent period 4 days shorter than that of RBSDV, implying a more efficient spread in insect vector. Currently, the mechanisms...

A potential panel of six-long non-coding RNA signature to improve survival prediction of diffuse large-B-cell lymphoma

, Zhaoyue Zhang, Hengqiang Zhao, Zhenzhen Wang & Meng Zhou AuthorsSearch for Jie Sun in:Nature Research journals • PubMed • Google ScholarSearch for Liang Cheng in:Nature Research journals • PubMed • Google ... journals • PubMed • Google ScholarSearch for Zhenzhen Wang in:Nature Research journals • PubMed • Google ScholarSearch for Meng Zhou in:Nature Research journals • PubMed • Google Scholar Contributions J.S

DisSim: an online system for exploring significant similar diseases and exhibiting potential therapeutic drugs

The similarity of pair-wise diseases reveals the molecular relationships between them. For example, similar diseases have the potential to be treated by common therapeutic chemicals (TCs). In this paper, we introduced DisSim, an online system for exploring similar diseases, and comparing corresponding TCs. Currently, DisSim implemented five state-of-the-art methods to measure the...

Integration of Multiple Genomic and Phenotype Data to Infer Novel miRNA-Disease Associations

MicroRNAs (miRNAs) play an important role in the development and progression of human diseases. The identification of disease-associated miRNAs will be helpful for understanding the molecular mechanisms of diseases at the post-transcriptional level. Based on different types of genomic data sources, computational methods for miRNA-disease association prediction have been proposed...

Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling

Glycosaminoglycans are important regulators of multiple signaling pathways. As a major constituent of the heart extracellular matrix, glycosaminoglycans are implicated in cardiac morphogenesis through interactions with different signaling morphogens. Ext1 is a glycosyltransferase responsible for heparan sulfate synthesis. Here, we evaluate the function of Ext1 in heart...

Identification and validation of potential prognostic lncRNA biomarkers for predicting survival in patients with multiple myeloma

Zhou 0 Hengqiang Zhao 0 Zhenzhen Wang 0 Liang Cheng Lei Yang Hongbo Shi Haixiu Yang Jie Sun 0 Equal contributors College of Bioinformatics Science and Technology, Harbin Medical University , Harbin

MicroRNA and Transcription Factor Mediated Regulatory Network Analysis Reveals Critical Regulators and Regulatory Modules in Myocardial Infarction

Myocardial infarction (MI) is a severe coronary artery disease and a leading cause of mortality and morbidity worldwide. However, the molecular mechanisms of MI have yet to be fully elucidated. In this study, we compiled MI-related genes, MI-related microRNAs (miRNAs) and known human transcription factors (TFs), and we then identified 1,232 feed-forward loops (FFLs) among these...

ER Stress Mediates TiAl6V4 Particle-Induced Peri-Implant Osteolysis by Promoting RANKL Expression in Fibroblasts

. Conceived and designed the experiments: Zhenheng Wang JZ NB HQ. Performed the experiments: Zhenheng Wang NL TS GZ Zhenzhen Wang JG. Analyzed the data: TG HQ. Contributed reagents/materials/analysis tools: NB

The Differences in Ultrasound and Clinicopathological Features between Basal-Like and Normal-Like Subtypes of Triple Negative Breast Cancer

Purpose The aim of this study was to identify the ultrasound features and clinicopathological characteristics of basal-like subtype of triple negative breast cancers (TNBCs). Materials and Methods This study was approved by the ethical board of the Second Affiliated Hospital of Harbin Medical University. The patients’ clinicopathological information was available. The ultrasound...

Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer

, and wrote the manuscript. Yanjun Qu, Rui Liu and Le Zhang reviewed and edited the manuscript. Ming Bai, Jialu Li, Tao Ning, Shaohua Ge, Zhenzhen Wang and Hongli Li performed some experiments. Yi Ba ... -24 overexpressing lentivirus or BCL2L11 overexpressing lentivirus were Haiyang Zhang, Jingjing Duan, Yanjun Qu, Ting Deng, Rui Liu, Le Zhang, Ming Bai, Jia Li, Zhenzhen Wang, Qian Fan, Guoguang Ying, l

Photodynamic therapy of a 2-methoxyestradiol tumor-targeting drug delivery system mediated by Asn-Gly-Arg in breast cancer

Photodynamic therapy of a 2-methoxyestradiol tumor-targeting drug delivery system mediated by Asn-Gly-Arg in breast cancer Jinjin Shi, Zhenzhen Wang, Lei Wang, Honghong Wang, Lulu Li, Xiaoyuan Yu

Endocytosis of adiponectin receptor 1 through a clathrin- and Rab5-dependent pathway

In eukaryotic cells, receptor endocytosis is a key event regulating signaling transduction. Adiponectin receptors belong to a new receptor family that is distinct from G-protein-coupled receptors and has critical roles in the pathogenesis of diabetes and metabolic syndrome. Here, we analyzed the endocytosis of adiponectin and adiponectin receptor 1 (AdipoR1) and found that they...

A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy

Project of Dermatology and Venereology, Jinan, Shandong 250000, ChinaFuren Zhang AuthorsSearch for Zhenzhen Wang in:Nature Research journals • PubMed • Google ScholarSearch for Yonghu Sun in:Nature Research

Analysis of POFUT1 Gene Mutation in a Chinese Family with Dowling-Degos Disease

Dowling-Degos disease (DDD) is an autosomal dominant genodermatosis characterized by reticular pigmented anomaly mainly affecting flexures. Though KRT5 has been identified to be the causal gene of DDD, the heterogeneity of this disease was displayed: for example, POFUT1 and POGLUT1 were recently identified and confirmed to be additional pathogenic genes of DDD. To identify other...

PAQR3 Modulates Insulin Signaling by Shunting Phosphoinositide 3-Kinase p110α to the Golgi Apparatus

Xiao Wang Lingdi Wang Lu Zhu Yi Pan Fei Xiao Weizhong Liu Zhenzhen Wang Feifan Guo Yong Liu Walter G. Thomas Yan Chen Phosphoinositide 3-kinase (PI3K) mediates insulin actions by relaying signals