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Tim-3 expression and its role in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common tumors in the world, and its mortality is still on the rise. Limited treatments and low chemotherapy sensitivity of HCC make new therapeutic strategies urgently needed. With the rise of immune checkpoint blockade, anti-CTLA-4 antibodies and anti-PD-1 antibodies have shown therapeutic effects in various tumors. T cell...

The Structural Analysis of the Determinants of Shanghai Real Estate Price

What are the factors that play the most significant role in affecting Shanghai real estate price? This essay has established an econometric model and uses the perspective of structural analysis to substantiate the real factors that affect the housing price in Shanghai during the 1994— 2015. The essay first collects data from multiple authoritative sources according to potential...

An Explorer of Chemical Biology of Plant Natural Products in Southwest China, Xiaojiang Hao

Xiaojiang Hao, who obtained Master Degree from Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS) in 1985, and Doctor in Pharmacy degree in Pharmacy from Institute for Chemical Research, Kyoto University, in 1990, was born in Chongqing in July, 1951. In 1991, he returned to KIB, CAS, as an Associate professor and served as the chair of the Department of...

Embankment Filling Loads on an Assembled Concrete Culvert beneath High Embankment

A culvert with prefabricated and assembled structural components is introduced to speed up the progress of highway construction in China. In order to clear the behavior of the prefabricated and assembled slab culvert, the center line section and the shoulder section of the embankment are selected for field tests. In the tests, the distribution and the growth of the earth...

Some new binary codes with improved minimum distances

It has been well-known that the class of quasi-cyclic (QC) codes contain many good codes. In this paper, a method to conduct a computer search for binary $2$-generator QC codes is presented, and a large number of good $2$-generator QC codes have been obtained. $5$ new binary QC codes that improve the lower bounds on minimum distance are presented. Furthermore, with new $2...

A tutorial on 5G and the progress in China

Telecommunications Technology (CATT) , Beijing 100191 , China 1 Project supported by the National Natural Science Foundation of China (No. 61425012) ORCID: Shan-zhi CHEN 5G has been developing at high speed since

Pneumonia in patients with cirrhosis: risk factors associated with mortality and predictive value of prognostic models

Cirrhosis always goes with profound immunity compromise, and makes those patients easily be the target of pneumonia. Cirrhotic patients with pneumonia have a dramatically increased mortality. To recognize the risk factors of mortality and to optimize stratification are critical for improving survival rate. Two hundred and three cirrhotic patients with pneumonia at a tertiary care...

Hybrid nanostructured particles via surfactant-free double miniemulsion polymerization

Chemistry of RWTH Aachen University, Forckenbeckstrasse 50, 52056, Aachen, GermanyYongliang Zhao, Junli Liu, Zhi Chen, Xiaomin Zhu & Martin Möller AuthorsSearch for Yongliang Zhao in:Nature Research journals ... • PubMed • Google Scholar Search for Junli Liu in:Nature Research journals • PubMed • Google Scholar Search for Zhi Chen in:Nature Research journals • PubMed • Google Scholar Search for Xiaomin Zhu

Using Plücker Coordinates for Pumping Speed Evaluation of Molecular Pump in the DSMC Method

In this study, the Plücker coordinates representation is used to formulate the ruled surface and the molecular path for pumping speed performance evaluation of a molecular vacuum pump. The ruled surface represented by the Pliicker coordinates is used to develop a criterion for when gas molecules hit the pump surface wall. The criterion is applied to analyze the flow rate of a new...

Network-based co-expression analysis for exploring the potential diagnostic biomarkers of metastatic melanoma

: Li-xin Wang, Guan-zhi Chen. Data curation: Li-xin Wang, Yang Li. Funding acquisition: Li-xin Wang. Methodology: Yang Li. Software: Yang Li. Validation: Li-xin Wang, Guan-zhi Chen. Visualization ... : Yang Li. 14 / 16 Writing ± original draft: Li-xin Wang. Writing ± review & editing: Guan-zhi Chen. 15 / 16 1. Institute NC . Melanoma Treatment±Health Professional Version (PDQ®) . 2016 2. Kanavy HE

The Effect of Geometrical Parameters on Resonance Characteristics of Acoustic Metamaterials with Negative Effective Modulus

addressed to Li-Mei Hao; nc.ude.tsux@mloah and Zhi Chen; nc.ude.upwn@z2002c Received 24 November 2017; Revised 7 February 2018; Accepted 28 February 2018; Published 4 April 2018 Academic Editor: Liyuan

Identification of cancer-related miRNA-lncRNA biomarkers using a basic miRNA-lncRNA network

. Writing ± review & editing: Zhi Chen, Yuanyuan Chen. 14 / 18 15 / 18 16 / 18 17 / 18 1. Wilusz J E, Sunwoo H , Spector D L. Long noncoding RNAs: functional surprises from the RNA world . Genes Dev . 2009

Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs of Lycoris radiata and Lycoricidine Derivatives

Fifteen known amaryllidaceae alkaloids were isolated from the bulbs of Lycoris radiata. Some of the compounds and lycoricidine derivatives had been screened for the activities against tobacco mosaic virus (TMV) by the conventional half-leaf method. Lycoricidine derivatives were also carried out the assay of effect on systemic infection of TMV by western-blot and RT-PCR analysis...

Salient object segmentation based on active contouring

Conceptualization: Xin Xia. Data curation: Zhi Chen, Hongyan Xu. Formal analysis: Xin Xia. Funding acquisition: Tao Lin. Resources: Zhi Chen. Software: Zhi Chen, Hongyan Xu. Writing ± original draft: Xin Xia

The Combined Effect of Nonalcoholic Fatty Liver Disease and Metabolic Syndrome on Osteoporosis in Postmenopausal Females in Eastern China

Da-Zhi Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ... ’ Contributions Da-Zhi Chen, Qiao-Mai Xu, and Xiao-Xin Wu contributed equally to this work. Acknowledgments This study was financed by research grants from the Chinese High Tech Research and Development (863

A degree-based block model and a local expansion optimization algorithm for anti-community detection in networks

. Funding acquisition: Changhong Yang, Wen Yang, Zhi Chen. Investigation: Jiajing Zhu. Methodology: Jiajing Zhu, Yongguo Liu, Yun Zhang. Project administration: Yongguo Liu, Wen Yang, Xindong Wu ... . Resources: Jiajing Zhu, Zhi Chen, Xindong Wu. Software: Changhong Yang, Zhi Chen, Yun Zhang, Shangming Yang. Supervision: Yongguo Liu, Wen Yang, Xindong Wu. Validation: Jiajing Zhu, Xindong Wu

Removal of arsenic from drinking water using rice husk

Rice husk adsorption column method has proved to be a promising solution for arsenic (As) removal over the other conventional methods. The present work investigates the potential of raw rice husk as an adsorbent for the removal of arsenic [As(V)] from drinking water. Effects of various operating parameters such as diameter of column, bed height, flow rate, initial arsenic feed...

Calculating the Mean Amplitude of Glycemic Excursions from Continuous Glucose Data Using an Open-Code Programmable Algorithm Based on the Integer Nonlinear Method

,2 Zhi Chen,2 Jun Jian,3 Bin Li,1 and Sherman Xuegang Xin4 1Southern Medical University, Guangzhou, China 2The Third Affiliated Hospital of Southern Medical University, Guangzhou, China 3Guangzhou

Calculating the Mean Amplitude of Glycemic Excursions from Continuous Glucose Data Using an Open-Code Programmable Algorithm Based on the Integer Nonlinear Method

,2 Zhi Chen,2 Jun Jian,3 Bin Li,1 and Sherman Xuegang Xin4 1Southern Medical University, Guangzhou, China 2The Third Affiliated Hospital of Southern Medical University, Guangzhou, China 3Guangzhou

Calculating the Mean Amplitude of Glycemic Excursions from Continuous Glucose Data Using an Open-Code Programmable Algorithm Based on the Integer Nonlinear Method

,2 Zhi Chen,2 Jun Jian,3 Bin Li,1 and Sherman Xuegang Xin4 1Southern Medical University, Guangzhou, China 2The Third Affiliated Hospital of Southern Medical University, Guangzhou, China 3Guangzhou