Advanced search    

Search: authors:"Zhi Gang Mao"

4 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Expression profiling of O 6 methylguanine-DNA-methyl transferase in prolactinomas: a correlative study of promoter methylation and pathological features in 136 cases

Background Low-level expression of O 6 methylguanine-DNA-methyl transferase (MGMT) prolactinomas has been noted previously in case reports, although what modulates MGMT expression remains unclear. This study therefore aimed to delineate the factors regulating MGMT expression in prolactinomas. Methods We retrospectively reviewed 136 prolactinoma patients who were treated in our...

Clinical applications of somatostatin analogs for growth hormone-secreting pituitary adenomas

Clinical applications of somatostatin analogs for growth hormone-secreting pituitary adenomas Ji-wen Wang,1,2 Ying Li,3 Zhi-gang Mao,1,2 Bin Hu,1,2 Xiao-bing Jiang,1,2 Bing-bing Song,4 Xin Wang,4

Differential expression of microRNAs in GH-secreting pituitary adenomas

Background The purpose of this study was to (1) identify specific miRNAs in growth hormones (GH)-secreting pituitary adenomas; (2) determine the relationship between the expression of these miRNAs and tumor size, somatostatin analogs treatment, and responsiveness to somatostatin analogs (SSA). Methods Fifteen GH-secreting adenomas patients were treated with lanreotide for 4...

Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells

Resistance of melanoma cells to chemotherapeutics remains a major obstacle to successful treatment of melanoma once it has spread beyond locoregional sites. We report in this study that activation of the unfolded protein response (UPR) is involved in resistance of melanoma cells to two chemotherapeutic drugs, cisplatin (CDDP) and adriamycin, and this is associated with glucose...