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23 papers found.
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Architecture mode, sedimentary evolution and controlling factors of deepwater turbidity channels: A case study of the M Oilfield in West Africa

Turbidity channels have been considered as one of the important types of deepwater reservoir, and the study of their architecture plays a key role in efficient development of an oil field. To better understand the reservoir architecture of the lower Congo Basin M oilfield, semi-quantitative–quantitative study on turbidity channel depositional architecture patterns in the middle...

Sequencing of complete mitochondrial genomes confirms synonymization of Hyalomma asiaticum asiaticum and kozlovi, and advances phylogenetic hypotheses for the Ixodidae

for the phylogenetic analyses. (TXT) Acknowledgments We would like to thank the anonymous reviewer for constructive and valuable comments. Author Contributions Conceptualization: Zhi-Qiang Liu, Yan ... -Feng Liu, Chuang-Fu Chen. Data curation: Zhi-Qiang Liu, Deng-Feng Wang, Jun-Wei Wang, Tao Han, Chen-Feng Shen. Formal analysis: Zhi-Qiang Liu, Li Zhao, Tao Han, Yuan-Zhi Wang. Funding acquisition: Zhi

Efficient biosynthesis of ethyl (R)-4-chloro-3-hydroxybutyrate using a stereoselective carbonyl reductase from Burkholderia gladioli

Background Ethyl (R)-4-chloro-3-hydroxybutyrate ((R)-CHBE) is a versatile chiral precursor for many pharmaceuticals. Although several biosynthesis strategies have been documented to convert ethyl 4-chloro-3-oxobutanoate (COBE) to (R)-CHBE, the catalytic efficiency and stereoselectivity are still too low to be scaled up for industrial applications. Due to the increasing demand of...

Enantioselective cascade biocatalysis for deracemization of 2-hydroxy acids using a three-enzyme system

Background Enantiopure 2-hydroxy acids are key intermediates for the synthesis of pharmaceuticals and fine chemicals. We present an enantioselective cascade biocatalysis using recombinant microbial cells for deracemization of racemic 2-hydroxy acids that allows for efficient production of enantiopure 2-hydroxy acids. Results The method was realized by a single recombinant...

A Way to Improve Luminescent Efficiency of Bis-Chalcone Derivatives

Kuan 1 Zhi-Qiang Liu 0 Artur M. S. Silva 0 State Key Laboratory of Crystal Materials, Shandong University , 27 Shanda South Road, Jinan 250100 , China 1 Department of Chemistry, Faculty of Resource

First report of Rickettsia raoultii and R. slovaca in Melophagus ovinus, the sheep ked

Background Melophagus ovinus (Diptera: Hippoboscidae), a hematophagous ectoparasite, is mainly found in Europe, Northwestern Africa, and Asia. This wingless fly infests sheep, rabbits, and red foxes, and causes inflammation, wool loss and skin damage. Furthermore, this parasite has been shown to transmit diseases, and plays a role as a vector. Herein, we investigated the presence...

First detection of Candidatus Rickettsia barbariae in the flea Vermipsylla alakurt from north-western China

Background Vermipsylla is a genus of the family Vermipsyllidae within the order Siphonaptera of fleas. Vermipsylla alakurt is mainly distributed in alpine pastoral areas of Kazakhstan, Mongolia, China and Nepal, and infests sheep, yaks and horses, causing irritation, poor condition, anaemia and even death. However, to date, no rickettsial agents have been reported in V. alakurt...

Vitamin D3 inhibits micro RNA-17-92 to promote specific immunotherapy in allergic rhinitis

-Qiang Liu Zhi-Gang Liu Da-Bo Liu Ping-ChangYang Hua-Bin Li OPEN It is recognized that T helper 2 (Th2) polarization plays a critical role in a large number of immune disorders.Yet, the remedies for

Global analysis of the ovarian microRNA transcriptome: implication for miR-2 and miR-133 regulation of oocyte meiosis in the Chinese mitten crab, Eriocheir sinensis (Crustacea:Decapoda)

Background MicroRNAs (miRNAs) are small non-coding RNA molecules that downregulate gene expression by base pairing to the 3′-untranslated region (UTR) of target messenger RNAs (mRNAs). Up to now, rare information for the miRNAs is available in decapod crustaceans. Our previous studies showed that many miRNA-binding sites are present in the 3′-UTR of the cyclin B in the Chinese...

Interleukin-13 interferes with activation-induced t-cell apoptosis by repressing p53 expression

Municipality (JCYJ20140418095735538 and JCYJ20140411150916749), and the Natural Science Foundation of SZU (No. 000004). AUTHORS’ CONTRIBUTION Li Yang, Ling-Zhi Xu, Zhi-Qiang Liu, Gui Yang, Xiao-Rui Geng, and

Association of GGCX gene polymorphism with warfarin dose in atrial fibrillation population in Xinjiang

0 Zhi-Qiang Liu 0 Peng-Yi He 0 0 Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University , Urumqi 830011 , P.R. China Objective: To study the effects of -glutamyl

Transcriptome sequencing and analysis of the entomopathogenic fungus Hirsutella sinensis isolated from Ophiocordyceps sinensis

Background Ophiocordyceps sinensis, a worm and fungus combined mixture which Hirsutella sinensis is parasitic on the caterpillar body, has been used as a traditional medicine or healthy food in China for thousands of years. H. sinensis is reported as the only correct anamorph of O. sinensis and its main active ingredients are similar to the natural O. sinensis. Results H...

Screening and Improving the Recombinant Nitrilases and Application in Biotransformation of Iminodiacetonitrile to Iminodiacetic Acid

In this study, several nitrilase genes from phylogenetically distinct organisms were expressed and purified in E. coli in order to study their ability to mediate the biotransformation of nitriles. We identified three nitrilases: Acidovorax facilis nitrilase (AcN); Alcaligenes fecalis nitrilase (AkN); and Rhodococcus rhodochrous nitrilase (RkN), which catalyzed iminodiacetonitrile...

Auto- and Cross-repression of Three Arabidopsis WRKY Transcription Factors WRKY18, WRKY40, and WRKY60 Negatively Involved in ABA Signaling

Some members of the WRKY transcription factor family are known to be involved in ABA signaling. However, it remains unclear how the WRKY transcription factors cooperate to regulate ABA signaling. In the present study, we showed that three Arabidopsis (A. thaliana) WRKY proteins previously identified as ABA signaling regulators, WRKY18, WRKY40, and WRKY60, directly target the W...

Mast cell-derived serine proteinase regulates T helper 2 polarization

Although mast cells play a critical role in allergic reactions, the cells are also involved in the protective immunity in the body. This study aims to investigate the role of mast cells in immune regulation during aberrant T helper (Th)2 responses. In this study, an adoptive antigen-specific Th2 response model was established with mast cell-deficient mice to test the role of mast...

TSP1-producing B cells show immune regulatory property and suppress allergy-related mucosal inflammation

, Xiao-Rui Geng, Gui Yang & Zhi-Qiang Liu AuthorsSearch for Huan-Ping Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Yingying Wu in:Nature Research journals • PubMed • Google ... • PubMed • Google ScholarSearch for Gui Yang in:Nature Research journals • PubMed • Google ScholarSearch for Lihua Mo in:Nature Research journals • PubMed • Google ScholarSearch for Zhi-Qiang Liu in:Nature

Stress-Derived Corticotropin Releasing Factor Breaches Epithelial Endotoxin Tolerance

Background and aims Loss of the endotoxin tolerance of intestinal epithelium contributes to a number of intestinal diseases. The etiology is not clear. Psychological stress is proposed to compromise the intestinal barrier function. The present study aims to elucidate the role of the stress-derived corticotropin releasing factor (CRF) in breaching the established intestinal...

A broad-range survey of ticks from livestock in Northern Xinjiang: changes in tick distribution and the isolation of Borrelia burgdorferi sensu stricto

Background Borreliosis is highly prevalent in Xinjiang Uygur Autonomous Region, China. However, little is known about the presence of Borrelia pathogens in tick species in this region, in addition Borrelia pathogens have not been isolated from domestic animals. Methods We collected adult ticks from domestic animals at 19 sampling sites in 14 counties in northern Xinjiang from...

HMGB1 Promotes Mitochondrial Dysfunction–Triggered Striatal Neurodegeneration via Autophagy and Apoptosis Activation

Impairments in mitochondrial energy metabolism are thought to be involved in many neurodegenerative diseases. The mitochondrial inhibitor 3-nitropropionic acid (3-NP) induces striatal pathology mimicking neurodegeneration in vivo. Previous studies showed that 3-NP also triggered autophagy activation and apoptosis. In this study, we focused on the high-mobility group box 1 (HMGB1...