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30 papers found.
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Experimental Study on Echo Characteristics of Multistatic Large-Scale Underwater Complex Target

Target acoustic scattering is the primary characteristic of target echo stealth performance, and it is an important sign of the viability of large-scale complex targets underwater. In a test band, owing to the superposition of scattered waves and the elastic echo produced by shells, liquid tanks, partition plates, ribs, etc., a target exhibits an extremely complex echo phenomenon...

Vitamin A and E Nutritional Status in Relation to Leptin, Adiponectin, IGF-I and IGF-II in Early Life - a Birth Cohort Study

The metabolic health effects of vitamin A and E nutritional status in early life are largely unknown. We assessed whether vitamin A and vitamin E nutritional status may affect circulating leptin, adiponectin, insulin-like growth factor (IGF)-I and IGF-II levels in early life in humans. In a singleton birth cohort (n = 248), vitamin A and E nutritional status in fetuses/newborns...

Impact of aortocaval shunt flow on cardiac and renal function in unilateral nephrectomized rats

function in unilateral nephrectomized rats Jie Wu Zhong Cheng Mingjing Zhang Pengfei Zhu Ye Gu OPEN We previously reported significantly enhanced cardiac remodeling post aortocaval fistula (AV) in

Macrosomia, Perinatal and Infant Mortality in Cree Communities in Quebec, 1996-2010

Background Cree births in Quebec are characterized by the highest reported prevalence of macrosomia (~35%) in the world. It is unclear whether Cree births are at greater elevated risk of perinatal and infant mortality than other First Nations relative to non-Aboriginal births in Quebec, and if macrosomia may be related. Methods This was a population-based retrospective birth...

Maternal Smoking and Metabolic Health Biomarkers in Newborns

Background Maternal smoking has been associated with elevated risk of type 2 diabetes among the offspring in adulthood. The mechanisms underlying this fetal “programming” effect remain unclear. The present study sought to explore whether maternal smoking affects metabolic health biomarkers in fetuses/newborns. Methods In a prospective singleton pregnancy cohort (n = 248), we...

Is Cesarean Delivery Preferable in Twin Pregnancies at >=36 Weeks Gestation?

Background The optimal mode of delivery in twin pregnancies remains controversial. A recent randomized trial did not find any benefit of planned cesarean vs. vaginal delivery at 32–38 weeks gestation, but the trial was not powered to detect a moderate effect. We aimed to evaluate the impact of cesarean delivery on perinatal mortality and severe neonatal morbidity in twin...

Aggravated Cardiac Remodeling post Aortocaval Fistula in Unilateral Nephrectomized Rats

Background Aortocaval fistula (AV) in rat is a unique model of volume-overload congestive heart failure and cardiac hypertrophy. Living donor kidney transplantation is regarded as beneficial to allograft recipients and not particularly detrimental to the donors. Impact of AV on animals with mild renal dysfunction is not fully understood. In this study, we explored the effects of...

Disparities and Trends in Birth Outcomes, Perinatal and Infant Mortality in Aboriginal vs. Non-Aboriginal Populations: A Population-Based Study in Quebec, Canada 1996–2010

Background Aboriginal populations are at substantially higher risks of adverse birth outcomes, perinatal and infant mortality than their non-Aboriginal counterparts even in developed countries including Australia, U.S. and Canada. There is a lack of data on recent trends in Canada. Methods We conducted a population-based retrospective cohort study (n = 254,410) using the linked...

Prevalence and risk factors of posttraumatic stress disorder among survivors five years after the “Wenchuan” earthquake in China

Objective The aim of this study was to investigate the prevalence of posttraumatic stress disorder (PTSD) and its risk factors among survivors in a heavily-hit area five years after the Wenchuan earthquake in 2008, China. Methods 684 survivors from Beichuan county, the center of the Wenchuan Earthquake in 2008, were evaluated using the PTSD Checklist-Civilian Version (PCL-C...

Influence of health-related quality of life on health service utilization in Chinese rural-to-urban female migrant workers

Lei 1 Zhong-Cheng Luo 0 0 Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital, Shanghai Jiao-Tong University School of Medicine , Shanghai , China 1

Is Gestational Hypertension Protective against Perinatal Mortality in Twin Pregnancies?

Background Pregnancy-induced or gestational hypertension is a common pregnancy complication. Paradoxically, gestational hypertension has been associated with a protective effect against perinatal mortality in twin pregnancies in analytic models (logistic regression) without accounting for survival time. Whether this effect is real remains uncertain. This study aimed to validate...

Association of uric acid with progression to preeclampsia and development of adverse conditions in gestational hypertensive pregnancies

William D. Fraser 0 Zhong-Cheng Luo 0 0 Department of Obstetrics and Gynecology , CHU Sainte-justine , University of Montreal , Montreal, Quebec , Canada 1 Department of Epidemiology , Tulane Bacgkround

Diabetes and Perinatal Mortality in Twin Pregnancies

BackgroundDiabetes in pregnancy has been associated with a paradoxically reduced risk of neonatal death in twin pregnancies. Risk “shift” may be a concern in that the reduction in neonatal deaths may be due to an increase in fetal deaths (stillbirths). This study aimed to clarify the impact of diabetes on the risk of perinatal death (neonatal death plus stillbirth) in twin...

Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis

ATP-binding cassette transporter A1 (ABCA1) plays a critical role in maintaining cellular cholesterol homeostasis. The purpose of this study is to identify the molecular mechanism(s) underlying ABCA1 epigenetic modification and determine its potential impact on ABCA1 expression in macrophage-derived foam cell formation and atherosclerosis development. DNA methylation induced foam...

Impact of Fetal and Infant Exposure to the Chinese Great Famine on the Risk of Hypertension in Adulthood

Background Famine provides quasi-experimental conditions for testing the hypothesis of “programming” health effects by poor nutrition in early life. It remains uncertain whether early life exposure to famine increases the risk of hypertension in adulthood. There is a lack of data on the relative impact of exposure to famine during fetal development versus infancy (<2 years...

Association between maternal comorbidity and preterm birth by severity and clinical subtype: retrospective cohort study

Background Preterm birth (PTB) is a major cause of infant morbidity and mortality, but the relationship between comorbidity and PTB by clinical subtype and severity of gestational age remains poorly understood. We evaluated associations between maternal comorbidities and PTB by clinical subtype and gestational age. Methods We conducted a retrospective cohort study of 1,329,737...

Circulating Docosahexaenoic Acid Levels Are Associated with Fetal Insulin Sensitivity

Zhong-Cheng Luo 0 Victor Sanchez-Margalet, Virgen Macarena University Hospital, School of Medicine, University of Seville, Spain 0 1 Department of Obstetrics and Gynecology, University of Montreal

A Randomized, Single-Center Double-Blinded Trial on the Effects of Diltiazem Sustained-Release Capsules in Patients with Coronary Slow Flow Phenomenon at 6-Month Follow-Up

Objective The aim of this study is to observe the chronic effects of diltiazem release capsules on patients with coronary slow flow (CSF) phenomenon. Methods From 2004 to 2009, 80 consecutive patients with chest pain and normal coronary arteries evidenced by coronary angiography and CSF were included in this randomized, double-blind, placebo-controlled trial. CSF patterns were...

Decreased Serum Hepcidin Concentration Correlates with Brain Iron Deposition in Patients with HBV-Related Cirrhosis

Purpose Excessive brain iron accumulation contributes to cognitive impairments in hepatitis B virus (HBV)-related cirrhotic patients. The underlying mechanism remains unclear. Hepcidin, a liver-produced, 25-aminoacid peptide, is the major regulator of systemic iron metabolism. Abnormal hepcidin level is a key factor in some body iron accumulation or deficiency disorders...

Reciprocal Interaction between Macrophages and T cells Stimulates IFN-γ and MCP-1 Production in Ang II-induced Cardiac Inflammation and Fibrosis

Background The inflammatory response plays a critical role in hypertension-induced cardiac remodeling. We aimed to study how interaction among inflammatory cells causes inflammatory responses in the process of hypertensive cardiac fibrosis. Methodology/Principal Findings Infusion of angiotensin II (Ang II, 1500 ng/kg/min) in mice rapidly induced the expression of interferon...