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Overexpression of Hypo-Phosphorylated IκBβ at Ser313 Protects the Heart against Sepsis

IκBβis an inhibitor of nuclear factor kappa B(NF-κB) and participates in the cardiac response to sepsis. However, the role of the hypo-phosphorylated form of IκBβ at Ser313, which can be detected during sepsis, is unknown. Here, we examined the effects of IκBβ with a mutation at Ser313→Ala313 on cardiac damage induced by sepsis. Transgenic (Tg) mice were generated to overexpress...

A new method of wound treatment: targeted therapy of skin wounds with reactive oxygen species-responsive nanoparticles containing SDF-1α

Ying-ying Liu,1 Zhong-shan Wang,1 Shi-chu Xiao,1 Cui Tang,3 Guang-Yi Wang,1 Zhao-Fan Xia1 1Department of Burn Surgery, The Second Military Medical University Affiliated Changhai Hospital, 2Department of ... Zhong-shan Wang 0 0 guang-Yi Wang Department of Burn surgery, The second Military Medical University Affiliated changhai hospital , shanghai 200433, People's republic of china Tel rom rseo PowerdbyTCPDF