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Search: authors:"Zhouyi Zheng"

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Maintenance therapy with all-trans retinoic acid and arsenic trioxide improves relapse-free survival in adults with low- to intermediate-risk acute promyelocytic leukemia who have achieved complete remission after consolidation therapy

remission after consolidation therapy Bin Liang,1,* Zhouyi Zheng,1,2,* Yifen Shi,1 Jingjing Chen,1 Xudong Hu,1 Honglan Qian,1 Zhijian Shen,1 Songfu Jiang,1 Kang Yu,1 Jianhua Feng1,3 1Division of Hematology

Histone Deacetylase Inhibitors Trichostatin A and MCP30 Relieve Benzene-Induced Hematotoxicity via Restoring Topoisomerase IIα

Dysfunction of histone acetylation inhibits topoisomerase IIα (Topo IIα), which is implicated in benzene-induced hematotoxicity in patients with chronic benzene exposure. Whether histone deacetylase (HDAC) inhibitors can relieve benzene-induced hematotoxicity remains unclear. Here we showed that hydroquinone, a main metabolite of benzene, increased the HDAC activity, decreased...