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Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways

Viral myocarditis is potentially fatal and lacking a specific treatment. Exosomes secreted by cardiac progenitor cells (CPCs) have emerged as a promising tool for cardioprotection and repair. In this study, we investigated whether CPCs-derived exosomes (CPCs-Ex) could utilize the mTOR signal pathway to reduce the apoptosis in viral myocarditis. In vitro, exosomes were...

Association of Thrombomodulin Gene C1418T Polymorphism with Susceptibility to Kawasaki Disease in Chinese Children

University, Changsha, Hunan 410013, China Correspondence should be addressed to Zuocheng Yang; moc.621@rcz_gnay Received 3 March 2018; Accepted 3 May 2018; Published 12 June 2018 Academic Editor: Michael

Association of Thrombomodulin Gene C1418T Polymorphism with Susceptibility to Kawasaki Disease in Chinese Children

University, Changsha, Hunan 410013, China Correspondence should be addressed to Zuocheng Yang; moc.621@rcz_gnay Received 3 March 2018; Accepted 3 May 2018; Published 12 June 2018 Academic Editor: Michael

The cytotoxicity of coxsackievirus B3 is associated with a blockage of autophagic flux mediated by reduced syntaxin 17 expression

Changsha , China 1 Department of Medicine, The Third Xiangya Hospital, Central South University , 410013 Changsha , China 2 Zuocheng Yang 3 Department of Pediatrics, Daping Hospital and Field Surgery

Association of PECAM-1 Gene Polymorphisms with Kawasaki Disease in Chinese Children

Xiangya Hospital of Central South University, Changsha, Hunan 410013, China Correspondence should be addressed to Zuocheng Yang; moc.621@rcz_gnay Received 19 November 2016; Revised 24 February 2017

A plasma mir-125a-5p as a novel biomarker for Kawasaki disease and induces apoptosis in HUVECs

Zuocheng Yang 0 1 0 Department of Pediatrics, The Third Xiangya Hosptial of Central South University , Changsha, Hunan , P.R. China 1 Editor: Ratna B. Ray, Saint Louis University , UNITED STATES Kawasaki