Hepatic Medicine : Evidence and Research

An international, peer-reviewed, open access, online journal.  Publishing original research, reports, editorials, reviews and commentaries on all aspects of adult and pediatric hepatology including pathology, pathophysiology of hepatic disease, investigation and treatment of hepatic disease, and pharmacology of drugs used for the treatment of hepatic disease.

List of Papers (Total 154)

Elbasvir/Grazoprevir for HCV Infection in Russia: A Randomized Trial

Konstantin Zhdanov,1 Vasily Isakov,2 Eduard Burnevich,3 Svetlana Kizhlo,4 Igor Bakulin,5 Vadim Pokrovsky,6 Liwen Liang,7 Peggy Hwang,7 Rohit Talwani,7 Barbara A Haber,7 Michael N Robertson7 1Military Medical Academy n.a. S.M. Kirov, St. Petersburg, Russia; 2Department of Gastroenterology & Hepatology, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow...

Management Strategies for Patients with Hilar Cholangiocarcinomas: Challenges and Solutions

Siddharth Mehrotra, Shailendra Lalwani, Samiran Nundy Department of Surgical Gastroenterology and Liver Transplantation, Sir Ganga Ram Hospital, New Delhi, IndiaCorrespondence: Samiran Nundy Email [email protected]: Advances in imaging, pathology and therapy have resulted in major improvements in the management of cholangiocarcinomas; the mortality has come down and with...

Project ECHO Revisited: Propensity Score Analysis And HCV Treatment Outcomes

Project ECHO Revisited: Propensity Score Analysis And HCV Treatment Outcomes

Analysis Of Risk Factors For Nonalcoholic Fatty-Liver Disease In Hepatitis B Virus Infection: A Case–Control Study

Ghodsiyeh Azarkar,1 Zahra Doosti,2 Freshteh Osmani,3 Masood Ziaee1 1Infectious Diseases Research Center, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran; 2Infectious Diseases and Tropical medicine Research center, Shahid Beheshti University of Medical Science, Tehran, Iran; 3Department of Epidemiology and Biostatistics, Faculty of Health, Birjand...

Seroprevalence and associated factors of hepatitis B virus infection among HIV-positive adults attending an antiretroviral treatment clinic at Wolaita Sodo University Referral Hospital

Seroprevalence and associated factors of hepatitis B virus infection among HIV-positive adults attending an antiretroviral treatment clinic at Wolaita Sodo University Referral Hospital

Impact of chronic schistosomiasis and HBV/HCV co-infection on the liver: current perspectives

Impact of chronic schistosomiasis and HBV/HCV co-infection on the liver: current perspectives

“Let my liver rather heat with wine” - a review of hepatic fibrosis pathophysiology and emerging therapeutics

Carlos G Moscoso,1 Clifford J Steer1,21Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition; 2Department of Genetics, Cell Biology and Development, University of Minnesota Medical School, Minneapolis, MN 55455, USACorrespondence: Carlos G Moscoso; Clifford J SteerDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University...

Impact of chronic schistosomiasis and HBV/HCV co-infection on the liver: current perspectives

Hanan Hassan Omar Clinical Pathology Department, Faculty of Medicine, Suez Canal University, Ismailia, EgyptCorrespondence: Hanan Hassan OmarClinical Pathology Department, Faculty of Medicine, Suez Canal University, Ismailia 41111, EgyptTel +20 109 362 7403Email [email protected]: Schistosomiasis is a public health problem in many countries. Its prevalence is...

The effect of a mesenchymal stem cell conditioned medium fraction on morphological characteristics of hepatocytes in acetaminophen-induced acute liver failure: a preliminary study

The effect of a mesenchymal stem cell conditioned medium fraction on morphological characteristics of hepatocytes in acetaminophen-induced acute liver failure: a preliminary study

Lysosomal acid lipase deficiency – early diagnosis is the key

Lysosomal acid lipase deficiency - early diagnosis is the key Georg Strebinger, Elena Müller, Alexandra Feldman, Elmar AignerFirst Department of Medicine, Paracelsus Medical University, Salzburg, AustriaAbstract: Lysosomal acid lipase deficiency (LAL-D) is an ultra-rare lysosomal storage disease that may present from infancy to late adulthood depending on residual enzyme activity...

Efficacy of direct-acting antiviral therapy for hepatitis C viral infection. Real-life experience in Bahrain

Efficacy of direct-acting antiviral therapy for hepatitis C viral infection. Real-life experience in Bahrain

Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom population

Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom population

Lysosomal acid lipase deficiency – early diagnosis is the key

Georg Strebinger, Elena Müller, Alexandra Feldman, Elmar AignerFirst Department of Medicine, Paracelsus Medical University, Salzburg, AustriaAbstract: Lysosomal acid lipase deficiency (LAL-D) is an ultra-rare lysosomal storage disease that may present from infancy to late adulthood depending on residual enzyme activity. While the severe form manifests as a rapidly progressive...

Cognitive impairment after liver transplantation: residual hepatic encephalopathy or posttransplant encephalopathy?

Cognitive impairment after liver transplantation: residual hepatic encephalopathy or posttransplant encephalopathy?

Ombitasvir, paritaprevir, and ritonavir with peginterferon-α2a plus ribavirin in treatment-experienced patients with chronic hepatitis C virus genotype 1 infection

Ombitasvir, paritaprevir, and ritonavir with peginterferon-alpha2a plus ribavirin in treatment-experienced patients with chronic hepatitis C virus genotype 1 infection

Ombitasvir, paritaprevir, and ritonavir with peginterferon-α2a plus ribavirin in treatment-experienced patients with chronic hepatitis C virus genotype 1 infection

David Bernstein,1 Rakesh Tripathi,2 Daniel E Cohen2 1Zucker School of Medicine, Hofstra University, Hempstead, New York, NY, USA; 2AbbVie Inc., North Chicago, IL, USA Background: This international, phase 2, open-label, multicenter study (ClinicalTrials.gov Identifier: NCT01609933) was conducted to evaluate the safety and efficacy of an enhanced regimen consisting of the direct...

Portosystemic shunts and refractory hepatic encephalopathy: patient selection and current options

Portosystemic shunts and refractory hepatic encephalopathy: patient selection and current options

Spontaneous bacterial peritonitis in patients with cirrhosis: incidence, outcomes, and treatment strategies

Spontaneous bacterial peritonitis in patients with cirrhosis: incidence, outcomes, and treatment strategies Sebastián Marciano,1,2 Juan Manuel Díaz,1 Melisa Dirchwolf,3 Adrián Gadano1,2 1Liver Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; 2Department of Research, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; 3Hepatology Unit, Hospital Privado de...

Practical steps to improve chronic hepatitis C treatment in people with opioid use disorder

Practical steps to improve chronic hepatitis C treatment in people with opioid use disorder Carlos Roncero,1 Pablo Ryan,2–4 Richard Littlewood,5 Juan Macías,6 Juan Ruiz,7 Pedro Seijo,8 Raúl Felipe Palma-Álvarez,9–11 Pablo Vega12,13 1Psychiatric Service, University of Salamanca Health Care Complex, Institute of Biomedicine of Salamanca, University of Salamanca, Salamanca, Spain...

Comparison of extracorporeal cellular therapy (ELAD®) vs standard of care in a randomized controlled clinical trial in treating Chinese subjects with acute-on-chronic liver failure

Comparison of extracorporeal cellular therapy (ELADreg) vs standard of care in a randomized controlled clinical trial in treating Chinese subjects with acute-on-chronic liver failure Zhongping Duan,1,* Shaojie Xin,2,* Jing Zhang,1 Shaoli You,2 Yu Chen,1 Hongling Liu,2 Sujun Zheng,1 Zheng Li,3 Robert Ashley,3 Michael Millis4 1Artificial Liver Center, Beijing You’an Hospital of...

Universal Index for Cirrhosis (UIC index): The development and validation of a novel index to predict advanced liver disease

Universal Index for Cirrhosis (UIC index): The development and validation of a novel index to predict advanced liver disease Zohair Ahmed,1 Jinma Ren,2 Adam Gonzalez,3 Umair Ahmed,4 Saqib Walayat,4 Daniel K Martin,5 Harsha Moole,4 Sherri Yong,6 Sean Koppe,7 Sonu Dhillon5 1Department of Gastroenterology and Hepatology, University of Illinois at Chicago, IL, USA; 2Department of...

Universal Index for Cirrhosis (UIC index): The development and validation of a novel index to predict advanced liver disease

Zohair Ahmed,1 Jinma Ren,2 Adam Gonzalez,3 Umair Ahmed,4 Saqib Walayat,4 Daniel K Martin,5 Harsha Moole,4 Sherri Yong,6 Sean Koppe,7 Sonu Dhillon5 1Department of Gastroenterology and Hepatology, University of Illinois at Chicago, IL, USA; 2Department of Center for Outcomes Research, University of Illinois College of Medicine, Peoria, IL, USA; 3University of Illinois College of...

Expert opinion on the management of hepatitis C infection in Kuwait

Expert opinion on the management of hepatitis C infection in Kuwait Motaz Fathy Saad,1 Saleh Alenezi,2 Haifaa Asker3 On behalf of the Kuwait Hepatology Club 1Haya Al-Habib Gastroenterology and Hepatology Center, Mubarak Alkabir Hospital, Hawaly, Kuwait; 2Unit of Gastroenterology and Hepatology, Department of Medicine, Farwaniya Hospital, Kuwait City, Kuwait; 3Thunayan Al-Ghanim...