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Valuing and mapping cork and carbon across land use scenarios in a Portuguese montado landscape

The ecosystem services approach can inform decision-making by accounting for both short- and long-term benefits from different land use options. Here we used the InVEST toolkit to quantify and map key ecosystem services at the largest publicly-owned agro-silvo-pastoral farmstead in Portugal–a site representative for the montado landscape. We analyzed how Provisioning (cork...

Bioconversion of fructus sophorae into 5,7,8,4’-tetrahydroxyis oflavone with Aspergillus aculeatus

A fungus identified as Aspergillus aculeatus was used to biotransform genistein and glycosides to polyhydroxylated isoflavones. The strain was identified on the basis of colony morphology features and ITS rDNA sequence analysis. Phylogenetic tree was constructed to determine its taxonomic status. Genistein and glycosides were transformed by Aspergillus aculeatus to 5,7,8,4...

Warranty of Seaworthiness--A Non-Seaman's Dilemma

In Watz v. Zapata Off-Shore Co., Judge Wisdom presents a well-articulated discussion pointed directly at the unsettled issue of when a ship is "in navigation". The significance of the court's determination is that the question of fact presented in this case is a close one, emphasizing an area never thoroughly considered by the Supreme Court; an area in need of further illumination.

The Osteocyte as a Novel Key Player in Understanding Periodontitis Through its Expression of RANKL and Sclerostin: a Review

Purpose of ReviewPeriodontitis is the inflammation-associated bone loss disease of the alveolar bone that surrounds teeth. Classically, the emphasis on the etiology of periodontitis has been on the products of periodontal pathogens that lead to an inflammatory response of the soft tissues of the periodontium, eventually leading to activation of osteoclasts that degrade the...

Amperometric biosensing system directly powered by button cell battery for lactate

The development of new signal systems for electrical biosensors could provide exciting new opportunities for biomedical analysis, pollutant monitoring, and explosive detection. The signal systems for commercial portable sensors involve the integration of a battery and a circuit conditioning system to power an amperometric biosensor. However, this increases the size and complexity...

Comparison between behavioral and structural explanation in learning by model-building

In science education, building models of dynamical systems is a promising method for understanding various natural phenomena and artifacts with scientific concepts. It is, however, difficult to learn skills and concepts necessary for modeling. Though several model-building learning environments (MBEs) have been developed with potentially useful methods for assisting students, the...

Funny Bone Jokes and Riddles (Martha Speaks)

Did you know that geckos eat their own skin? Gecko follows a little critter by the same name as it goes about its daily life, detailing its many daily activities. In a single day, a gecko could be shedding and eating its own skin, camouflaging, catching dinner, escaping from a scuffle with a rat (tail not intact), and finally defending its turf before settling down to a good...

Outcomes of ureteroscopy (URS) for stone disease in the paediatric population: results of over 100 URS procedures from a UK tertiary centre

PurposeTo report the outcomes of paediatric ureteroscopy (URS) for stone disease from a specialist endourology centre in the UK. Ureteroscopy for management of stone disease has increased worldwide and is now being done more commonly in the paediatric age group.MethodsData were analysed retrospectively from a database maintained between April 2010 and May 2018. Consecutive...

Ex vivo-expanded highly purified natural killer cells in combination with temozolomide induce antitumor effects in human glioblastoma cells in vitro

Glioblastoma is the leading malignant glioma with a poor prognosis. This study aimed to investigate the antitumor effects of natural killer cells in combination with temozolomide as the standard chemotherapeutic agent for glioblastoma. Using a simple, feeder-less, and chemically defined culture method, we expanded human peripheral blood mononuclear cells and assessed the receptor...

Stem cells in human breast milk

Recent studies have demonstrated that breast milk contains a population of cells displaying many of the properties typical of stem cells. This review outlines progress made in this newly emerging field of stem cell biology and provides an analysis of the available data on purification, propagation and differentiation of certain types of progenitor cells from breast milk. The...

FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele

FBXO7 encodes an F box containing protein that interacts with multiple partners to facilitate numerous cellular processes and has a canonical role as part of an SCF E3 ubiquitin ligase complex. Mutation of FBXO7 is responsible for an early onset Parkinsonian pyramidal syndrome and genome-wide association studies have linked variants in FBXO7 to erythroid traits. A putative...

Time and Frequency Domain Simulation, Measurement and Optimization of Log-Periodic Antennas

Log-periodic antenna is a special antenna type utilized with great success in many broadband applications due to its ability to achieve nearly constant gain over a wide frequency range. Such antennas are extensively used in electromagnetic compatibility measurements, spectrum monitoring and TV reception. In this study, a log-periodic dipole array is measured, simulated, and then...

Adverse stroke outcomes among patients with bipolar disorder

Failure to deliver the standard stroke care is suspected to be a potential reason for disproportionately high mortality among patients with co-morbid bipolar disorder (BD). Few studies have explored adverse outcomes and medical care costs concurrently (as a proxy for care intensity) among patients with BD admitted for stroke. Data for this nationwide population-based study were...

Testimony Under Threat: Women’s Voices and the Pursuit of Justice in Post-War Sri Lanka

This paper foregrounds how women’s public testimony as part of a formal transitional justice initiative is shaped by the particular context in which a commission operate, including the political and security environment. While the literature has engaged with the gendered predicaments of truth commissions after peace agreements and during transitions away from non-democratic rule...

Memories and prevalence of posttraumatic stress disorder in intensive care units

The present study evaluated the prevalence of PTSD indicators in patients who had to be hospitalized in ICU six months after being discharged and examined the relationship between PTSD and mnemonic memories. Participants were 41 adult patients with different diseases who answered questionnaires about PTSD, memory and clinical information. It was identified that 24.4% of the...

An EU-wide approach to HTA: An irrelevant development or an opportunity not to be missed?

An EU-wide cooperation on HTA has been proposed recently by the European Commission, focusing on relative effectiveness assessment (REA) for pharmaceuticals and medical devices. This cooperation is operationalised through a proposal for a regulation. While a good step in the right direction, this HTA cooperation framework needs to be more explicit and pragmatic about clinical...

Evidence for a bind-then-bend mechanism for architectural DNA binding protein yNhp6A

The yeast Nhp6A protein (yNhp6A) is a member of the eukaryotic HMGB family of chromatin factors that enhance apparent DNA flexibility. yNhp6A binds DNA nonspecifically with nM affinity, sharply bending DNA by >60°. It is not known whether the protein binds to unbent DNA and then deforms it, or if bent DNA conformations are ‘captured’ by protein binding. The former mechanism would...

SWEET MAPS: A Conceptualization of Low-Calorie Sweetener Consumption Among Young Adults

The extent to which low-calorie sweeteners (LCSs) are helpful or harmful for weight management and metabolic health is unclear, because LCS effects may depend on the context in which they are consumed.

Silk fibroin hydrogels from the Colombian silkworm Bombyx mori L: Evaluation of physicochemical properties

Hydrogel scaffolds are important materials in tissue engineering, and their characterization is essential to determine potential biomedical applications according to their mechanical and structural behavior. In this work, silk fibroin hydrogels were synthesized by two different methods (vortex and sonication), and agarose hydrogels were also obtained for comparison purposes...

Functional mitral regurgitation

Dr. O.P. Yadava, Editor-in-Chief, IJTC, and Dr. J.L. Pomar, Former President, EACTS, discuss issues related to secondary mitral regurgitation (MR). Though it is considered a ventricular disease, mitral valve leaflets are not entirely normal. Alignment of subvalvular apparatus plays a more dominant role than annular dilatation. Early repair is preferred.

TNF-α G-308A genetic variants, serum CRP-hs concentration and DNA damage in obese women

Obesity is associated with inflammation, which can disturb genome stability. Tumor necrosis factor (TNF-α) polymorphism was found to affect TNF-α protein production and inflammation. Therefore, the present study illustrates the relationship between TNF-α polymorphism, the degree of inflammation assessed by serum high sensitivity C-reactive protein concentration (CRP-hs) and basal...

Effect of physical activity on the cardiometabolic profiles of non-obese and obese subjects: Results from the Korea National Health and Nutritional Examination Survey

Background Physical inactivity is an important but often neglected risk factor for various cardiovascular diseases. We hypothesized that physical inactivity might have deleterious effects on metabolic health in obese and non-obese subjects. Methods We evaluated the effect of physical activity on the cardiometabolic profiles of a nationwide cohort of non-obese and obese...

A new higher order GUP: one dimensional quantum system

In this paper we present a new higher order generalized (gravitational) uncertainty principle (GUP*) which has the maximal momentum as well as the minimal length. We discuss the position representation and momentum representation. We also discuss the position eigenfunction and maximal localization states. As examples we discuss one dimensional box problem and harmonic oscillator...

Basking

By Olivia Corso, Published on 04/08/19

Functional diversity of predators and parasitoids does not explain aphid biocontrol efficiency

Many studies demonstrate an important role of natural enemy biodiversity in the regulation of agricultural pests, but the role of different aspects of biodiversity in influencing this crucial ecosystem service remain controversial. We hypothesised that the functional diversity generated by combining divergent consumer groups (roaming coccinellid predators and parasitoid wasps...

A25 ASSOCIATION OF BIOLOGIC PRESCRIBING FOR INFLAMMATORY BOWEL DISEASE WITH INDUSTRY PAYMENTS TO PHYSICIANS

Financial conflicts of interest (FCOIs) between the pharmaceutical industry and physicians have been associated with changes in prescribing behaviour, though the nature of this association in inflammatory bowel disease (IBD) is unknown.

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