A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms

Understanding biological systems requires observing features and processes across vast spatial and temporal scales, spanning nanometers to centimeters and milliseconds to days, often using multiple imaging modalities within complex native microenvironments. Yet, achieving this comprehensive view is challenging because microscopes optimized for specific tasks typically lack...

WAYS TO IMPROVE THE RELIABILITY OF TRANSMISSION UNITS AND ASSEMBLIES IN BTR-4 SERIES WHEELED ARMORED PERSONNEL CARRIERS

This paper investigates the causes of failures in transmission units and assemblies of BTR-4 series wheeled armored personnel carriers, with particular emphasis on inter-axle and inter-wheel differentials during operation. The sources of static and dynamic loads acting on the units and assemblies of a hydromechanical transmission in a four-axle wheeled vehicle are examined. Based...

Enhanced geometry control powered by AI for UAVS with a robotic arm for compensating for disturbances

Unmanned Aerial Vehicles (UAVs) equipped with robotic manipulators have emerged as a powerful paradigm for advanced aerial manipulation tasks, including infrastructure inspection, emergency response, and precise object handling in hazardous or inaccessible environments. Despite their potential, integrating robotic arms introduces significant challenges due to strong dynamic...

Kontribusi Komponen Pendapatan Asli Daerah (PAD) Terhadap Realisasi PAD Kabupaten Lamongan Tahun 2020-2024

Regional Original Revenue (PAD) is a key indicator in assessing the fiscal independence of a region. However, the contribution of each PAD component to total PAD realization tends to fluctuate and has not yet reached optimal levels, making it necessary to conduct an analysis to identify the most dominant components and observe their contribution trends over time. This study aims...

BookTok as a Catalyst for Reading Activity: Challenges and Opportunities for Promoting Library Funds in Ukraine

The aim of the article is to study the specifics of the BookTok phenomenon’s influence on reading activity, as well as to ground strategies for adapting libraries to new conditions of promoting book funds in Ukraine. Research methods. The methodological framework of the study comprises a set of general scientific and specialised methods: analysis, synthesis, generalisation (for...

Publisher Correction: Unveiling hidden risks in healthcare from flood-induced transportation disruption in Germany

FLRT2 promotes foam cell formation and atherosclerosis by inhibiting USP22-mediated ABCA1 deubiquitination

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of foam cells within the arterial wall. Despite substantial progress, the molecular mechanisms governing foam cell formation remain incompletely understood. Here, we identify fibronectin leucine-rich transmembrane protein 2 (FLRT2) as a previously unrecognized regulator of macrophage-driven...

Pathomolecular characterization of recently isolated duck Astrovirus from domestic ducklings in Egypt

Astrovirus infection significantly impacts poultry production due to its fatal effect on young birds and their ability to be transmitted by horizontal and vertical routes. In the current study, eight Egyptian duckling farms from different breeds (Moulard, Muscovy, and Pekin) with a history of sudden death accompanied by neurological signs with marked hepatitis lesions at Al...

CALCULATION-EXPERIMENTAL STUDIES OF THE RESPONSE OF TORSION SHAFTS OF SUSPENSION SYSTEMS OF LIGHT ARMORED VEHICLES TO THE ACTION OF LOAD

The article presents the results of computational and experimental studies of the response of torsion shafts of suspension systems of light armored vehicles to the action of loading, taking into account the complex interaction of their main elements. The study is aimed at overcoming the limitations of traditional approaches, which are mainly focused on the analysis of the torsion...

Financial Literacy, Lifestyle, And Parental Income On Financial Management Behavior With Self-Control As A Mediating Variable (Case Study of College Students in Malang City)

This study aims to analyze the influence of financial literacy, lifestyle, and parental income on financial management behavior, with self-control as an intervening variable among college students in Malang City. Using a quantitative explanatory research approach, data were collected through questionnaires from 160 respondents and analyzed using SEM-PLS. The results showed that...

Efektivitas Pembeajaran Sport Massage Terhadap Cara Pemulihan Kondisi Fisik Sesudah Pertandingan Sepak Bola Antar Mahasiswa

Seiring berjalannya waktu, olahraga merata di penjuru dunia. Olahraga berkembang begitu pesat terutama di Indonesia. Di Indonesia sendiri olahraga yang paling populer adalah olahraga sepak bola. Hampir kita temui di berbagai daerah setiap sore masyarakat mengisi waktu menunggu magrib dengan berolahraga sepak bola. Dan dipastikan masyarakat indonesia dunia juga sangat mengenal...

Library in the System of Digital Representation of Cultural Heritage

The aim of the article is to define structural components of the system of digital representation of cultural heritage and to clarify the role of libraries as subjects of such activities. This study focuses on the analysis of interaction among cultural heritage objects, representative institutions, specialists, technological infrastructure, functional processes and users, which...

The miR4261/PAMM axis in multiple myeloma promotes bone resorption

This study investigates the mechanisms underlying myeloma bone disease (MBD) in multiple myeloma (MM), focusing on myeloma cell-derived exosomes and liquid biopsy biomarkers to identify therapeutic targets for reducing osteoclast activity and enhancing bone homeostasis. Co-culture of OPM2, RPMI 8226, and NCI-H929 myeloma cell lines with THP-1 cells was employed to assess miR4261...

Large-scale screening of high-entropy materials for superionic solid electrolytes

Solid electrolytes have emerged as a promising alternative to conventional liquid electrolytes that have posed safety concerns. However, the relatively low ionic conductivity of solid electrolytes is one of the challenges for their practical application. In this work, we study high-entropy materials over a wide chemical space as a combinatorial strategy to enhance the ionic...

THE EFFECT OF THE STIFFNESS PROPERTIES OF SURFACE LAYERS ON THE CONTACT INTERACTION BETWEEN BODIES AND SURFACES OF SIMILAR SHAPE

In many machine-building structures, parts that are in contact interaction are widespread. In many cases, such interaction occurs on surfaces that nominally coincide or are close. That is, the gap between the bodies is nominally either zero or very small. In these cases, two factors become important factors. The first is the contact stiffness, which is determined by the...

The contribution of soil extract composition and cyclic moisture dynamics to the physicochemical aging of superabsorbent polyacrylic acid and polyacrylamide hydrogels

Polyacrylic acid (PAA) and polyacrylamide (PAM), two synthetic superabsorbent polymers (SAPs) commonly used, inter alia, in agriculture, can form three‑dimensional hydrogels that enhance soil water retention and soil structural stability. Yet, their potential aging and transformation under natural drying-rewetting dynamics and in contact with soil solutes remain unclear. In this...

Analysis of Curriculum Development Models and Approaches in the Perspective of Modern Education

This study aims to analyze curriculum development models and approaches from a modern educational perspective and their contribution to improving the quality of learning. The study used a qualitative approach with library research through the review of various relevant literature sources, such as scientific books, journal articles, and previous research results. Data analysis was...

DIDACTIC FEATURES OF MORAL TEACHINGS IN YUSUF KHOS HAJIB’S EPIC POEM “KUTADGU BILIG”

This article analyzes the didactic features of moral teachings expressed in Yusuf Khos Hajib’s epic poem Kutadgu Bilig. The work explores such issues as human perfection, morality, wisdom, justice, contentment, parental responsibility, child upbringing, speech etiquette, social relations, and the idea of the perfect human being in a poetic and didactic manner. Kutadgu Bilig is...

Big Data Analytics in the Library Environment

The aim of the article is to study and characterise the role of Big Data analytics in the digitalisation of library processes, in particular, personalisation of services, demand forecasting, and resource optimisation. Research methods. This study uses general scientific (review, analysis/synthesis, system approach, comparative analysis, generalisation) and special (analytical...

Silencing or strengthening? Ostracism and far-right radicalization of public figures. A mixed-method case study of a German civil rights activist

This paper examines the intellectual radicalization of a prominent German civil rights activist who, over the course of a decade, increasingly aligned with far-right ideologies. It asks how public ostracism shapes the radicalization trajectories of public figures who adopt far-right positions: does it prompt reputational repair and moderation, or does it instead deepen...

Changes in gut microbiota composition following water kefir consumption in healthy adults

Fermented foods have gained increasing scientific interest for their potential to modulate gut microbiota and provide probiotic microorganisms with possible health benefits. This intervention trial examined the impact of daily consumption of water kefir, a sustainable plant-based fermented beverage, on gut microbiota composition in 40 healthy adults. Participants consumed 200 mL...

EFFECT OF TEMPERATURE ON THE MECHANICAL PROPERTIES OF VACUUM-MELTED COPPER FOIL

Increasing the reliability of assemblies and structures, the efficiency of machines and equipment for various purposes require the development and application of new materials that are capable of operating in difficult conditions at low or high temperatures, in aggressive environments, under heavy loads, in particular, high-strength metals and alloys, composite and non-metallic...

When screening and diagnosis converge: participant interpretations of additional findings in the 100,000 genomes project

Genomic science is a central feature of the UK government’s current 10-year health plan for England, which places significant emphasis on prediction and prevention. Although NHS prevention strategies have long been aimed at catching diseases earlier and at a more treatable stage, genomics until now has focussed largely on diagnosis and treatment. At present, there is limited...

A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines

The activation of pattern recognition receptors (PRRs) orchestrates inflammation and regulates adaptive immunity. To test whether tuning inflammation through PRR stimulation enhanced the efficacy of mRNA vaccines, we combined an mRNA-based vaccine generated against the ancestral spike protein of SARS-CoV-2 with mannadjuvant, a formulation of fungal mannan and aluminum hydroxide...

Library Science Terminology: Research Historiography

The aim of the article is to identify and evaluate scientific works on library science terminology, as well as to determine key features of individual stages of its development. Research methods. The article employs the following methods: content analysis to identify and analyse scientific works on the issues of library science terminology; historical-comparative method to...

Analysis Of The Influence Of Product Quality And Promotion & Reward Programs On Customer Loyalty Through Customer Satisfaction In Gold Savings Customers At BSI: Systematic Literature Review (SLR) With Bibliometrics

This study aims to analyze the influence of product quality and promotion and reward programs on customer loyalty through customer satisfaction in gold savings customers at Bank Syariah Indonesia (BSI) using the Systematic Literature Review (SLR) approach combined with bibliometric analysis. This study examines scientific articles published in the 2020–2025 range from various...

Heart disease diagnosis and categorization from ECG signals using hybrid Fuzzy-CNN machine optimized by meta-heuristic algorithms

Cardiovascular diseases are among the most important causes of global mortality, and their diagnosis is mainly based on ECG signals. The complexity and nonlinearity of these signals have limited the effectiveness of classical machine learning methods. In this study, an optimized hybrid model based on Fuzzy-CNN is presented using meta-heuristic algorithms for classifying 2D images...

Tumor irradiation promotes antigen dressing of dendritic cells to enhance CAR T cell persistence and efficacy in lung metastases

Metastatic solid tumors remain the principal cause of cancer mortality worldwide. High tumor burden impairs responses to chimeric antigen receptor (CAR) T cell therapy, yet off-tumor toxicity limits the doses that can be safely delivered. Strategies to selectively enhance CAR T cell activity at tumor sites could widen the therapeutic window. Using syngeneic models of extensive...

NON-AXISYMMETRIC THERMOELASTOPLASTIC STATE OF BRANCHED SHELLS OF REVOLUTION: A SEMI-ANALYTICAL FINITE ELEMENT METHOD

A methodology for the analysis of the non-axisymmetric thermoelastoplastic stress–strain state of shells of revolution with a branched meridian is presented. The problem is solved using the semi-analytical finite element method in combination with the Kirchhoff–Love hypotheses. The solution is obtained in a quasi-static uncoupled formulation within the framework of geometrically...

Pengaruh Pengajaran Teknik Sport Massage Dalam Mengatasi Kebugaran Jasmani Pemain Pada Pertandingan Bola Basket Mahasiswa Pendidikan Jasmani Kesehatan Dan Rekreasi

Sport massage merupakan teknik pijat khusus yang bertujuan untuk meningkatkan kondisi fisik atlet dengan cara mengurangi ketegangan otot, meningkatkan sirkulasi darah, serta membantu proses pemulihan setelah latihan maupun pertandingan. Penelitian ini bertujuan untuk menganalisis pentingnya pemahaman teknik sport massage bagi atlet serta bagaimana penguasaan teknik tersebut dapat...