Fibroblast growth factors (FGFs) are a family of 22 human cytokines involved in critical cellular processes, such as proliferation, differentiation, metabolism, angiogenesis, tumor metastasis, and wound healing. Among these, fibroblast growth factor 1 (FGF1) possesses a powerful mitogenic potential as it can nonspecifically bind to all four FGF receptors. However, the therapeutic...
By Inquiry Editors, Published on 01/01/24
By Inquiry Editors, Published on 01/01/24
By Inquiry Editors, Published on 01/01/24
By Inquiry Editors, Published on 01/01/24
On October 4, 1921, Sure Pop Oil Company held a barbecue to celebrate the newly built oil derrick and attract new investors in Eureka Springs, Arkansas. The Eureka Springs Historical Museum has photos from the celebration. Local lore suggests that the oil company owners were "confidence men
Anginex is a cytokine-like β-sheet forming peptide of 33 amino acids with potent anti-angiogenic activity.Anginex is essential in inhibiting abnormal processes caused by angiogenesis, such as tumor growth and blood vessel formation. However, Anginex has limitations, including poor stability, short half-life, complicated synthesis, and low purity. Rubredoxin dimer (RdRd) is used...
By Inquiry Editors, Published on 01/01/23
By Inquiry Editors, Published on 01/01/23
By Inquiry Editors, Published on 01/01/23
Excessive concentrations of the natural aromatic amino acids phenylalanine and tyrosine are characteristic of the severe genetic abnormalities known as phenylketonuria (PKU) and tyrosinemia, respectively. Within this context, this feature article authenticates claims that tryptophan can form amyloid-like supramolecular structures in vitro and is the first to propose potential...
By Inquiry Editors, Published on 05/24/23
By Inquiry Editors, Published on 05/24/23
By Inquiry Editors, Published on 05/24/23
By Inquiry Editors, Published on 05/24/23
By Inquiry Editors, Published on 05/24/23
Plant elicitor peptides (Peps) – endogenous chains of amino acids involved in natural plant defense – have been shown to decrease damage from herbivores and pathogens by inducing an immune response, increasing the emission of volatile organic compounds (VOCS), transcripts, and metabolites. Exogenous treatment of soybean seeds with plant elicitor peptide GmPep3 has been shown to...
By Inquiry Editors, Published on 01/01/22
By Inquiry Editors, Published on 01/01/22
By Inquiry Editors, Published on 01/01/22