Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive and irreversible loss of cognitive function. The presence of senile plaques is one of the pathological markers of the disease and is associated with the onset of neuroinflammatory mechanisms. The exact pathophysiology of AD has not been completely understood, and there are no...
Background: Motor functional neurological disorder (mFND) is a common and disabling condition. There are no evidence-based guidelines for treatment. Long-term outcome is often poor. This study describes the epidemiological profile, symptom pattern and outcome of patients admitted to the Belo Horizonte unit of the SARAH Network of Rehabilitation Hospitals from 1997 to 2018 with...
Background:Telemedicine was first introduced in Neurology as a tool to facilitate access to acute stroke treatment. More recently, evidence has emerged of the use of telemedicine in several other areas of Neurology. With the advent of the COVID-19 pandemic and the need for social isolation, Brazilian authorities have expanded the regulation of the use of telemedicine, thus...
IMAGES IN NEUROLOGYNeuroimaging and ophthalmologic findings in incomplete Susac syndromeNeuroimagem e achados oftalmológicos na síndrome de Susac incompletaRenata Cristina MÜLLER1 http://orcid.org/0000-0002-6602-2101Kenzo HOKAZONO2 http://orcid.org/0000-0003-2897-6833Bernardo Corrêa de Almeida TEIXEIRA1 http://orcid.org/0000-0003-4769-6562Rosana Hermínia SCOLA3 http://orcid.org...
Images in NeurologyAcute parkinsonism and bilateral basal ganglia lesionsParkinsonismo agudo e lesão bilateral nos núcleos da baseRodrigo Alencar e SILVA1 http://orcid.org/0000-0002-3311-0164Thadeu Alexandre Paulino DE SOUSA2 http://orcid.org/0000-0001-9568-3411Clécio GODEIRO-JUNIOR1 http://orcid.org/0000-0002-4312-16331Universidade Federal do Rio Grande do Norte, Hospital...
Images in NeurologyMalignant cerebral edema: an unusual neurological manifestation of systemic lupus erythematosusEdema cerebral maligno: uma manifestação neurológica atípica do lúpus eritematoso sistêmicoMarianna Pinheiro Moraes De Moraes1 http://orcid.org/0000-0003-1273-9083Barbara Trapp2 http://orcid.org/0000-0001-5554-6674Flávio Moura Rezende Filho1 http://orcid.org/0000-0003...
The authors review the role of Jules Bernard Luys in the discovery of the subthalamic nucleus (STN) over 150 years ago. The relationships between the STN and movement disorders, particularly hemiballismus and Parkinson’s disease, are well known. The academic life of Jules Bernard Luys can be divided into two periods: a brilliant start as a neuroanatomist, culminating in the...
Background:Neurological manifestations of COVID-19 are still incompletely understood. Neurological manifestations may be due to direct viral effect on neurons and glial cells, to an immune-mediated response to the virus, or to a hypercoagulable state and associated endothelial damage, as well as to severe systemic disease with prolonged intensive care unit stay.Objective:To...
Importance:Hypertrophic pachymeningitis (HP) is a non-usual manifestation of rheumatologic, infectious, and neoplastic diseases. Etiological diagnosis is a challenge, but when made promptly it creates a window of opportunity for treatment, with the possibility of a total reversal of symptoms.Observations:HP is an inflammatory process of the dura mater that can occur as a...
Introduction: Magnetic resonance imaging (MRI) is the most important tool for diagnosis and follow-up in multiple sclerosis (MS). The discrimination of relapsing-remitting MS (RRMS) from secondary progressive MS (SPMS) is clinically difficult, and developing the proposal presented in this study would contribute to the process.Objective: This study aimed to ensure the automatic...
Objective: Uric acid has been shown to be related to the severity of obstructive sleep apnoea syndrome (OSAS) in adults. We assessed the role of uric acid in OSAS in a cohort of older patients.Methods: A total of 164 patients aged >65 years, admitted to our sleep laboratory between January 1st, 2016 and July 1st, 2018 with a complaint of snoring, underwent overnight...
Background: Migraine is one of the most common disorders in neurological clinical practice and is part of the group of primary headaches. It often affects individuals in the age group of 25-55 years, when people are at their peak of economic productivity. Many patients ultimately overuse analgesics. Overuse is defined by the use of analgesics for at least 15 times a month...
Introduction: We aimed to identify sleep disorders in patients with epilepsy and compare this group with a healthy population. We also analyzed the features of sleep disorders in patients with epilepsy to demonstrate the effect of seizures and seizure types on sleep.Methods: Our study assessed 43 patients with epilepsy and 53 age- and gender-matched healthy controls. The...
Introduction:Dementia is a globally relevant health problem, which places a great burden on patients and their families. This study aimed to estimate the burden associated with Alzheimer's disease (AD) and other dementias in Brazil.Methods:In this descriptive study, we investigated the estimates obtained by the Global Burden of Disease study. We described the prevalence of AD and...
Background: The rapid evaluation of non-contrast-enhanced computed tomography (NCCT) brain scans in patients with anterior stroke symptoms saves time and favors optimal and prompt treatment. e-ASPECTS is a tool that automatically calculates the Alberta Stroke Program Early CT Score (ASPECTS) values, leading to a more accurate and timely image evaluation.Objective: To determine...
EditorialBurden of dementia in BrazilCarga de demência no BrasilRicardo NITRINI1 http://orcid.org/0000-0002-5721-1525Cleusa P. FERRI2 http://orcid.org/0000-0002-1815-76851Universidade de São Paulo, Medical School, Department of Neurology, São Paulo SP, Brazil.2Universidade Federal de São Paulo, Department of Psychiatry, São Paulo SP, Brazil.The paper by Melo et al.1 is an...
IMAGES IN NEUROLOGYNeuroimaging and ophthalmologic findings in incomplete Susac syndromeNeuroimagem e achados oftalmológicos na síndrome de Susac incompletaRenata Cristina MÜLLER1 http://orcid.org/0000-0002-6602-2101Kenzo HOKAZONO2 http://orcid.org/0000-0003-2897-6833Bernardo Corrêa de Almeida TEIXEIRA1 http://orcid.org/0000-0003-4769-6562Rosana Hermínia SCOLA3 http://orcid.org...
Images in NeurologyAcute parkinsonism and bilateral basal ganglia lesionsParkinsonismo agudo e lesão bilateral nos núcleos da baseRodrigo Alencar e SILVA1 http://orcid.org/0000-0002-3311-0164Thadeu Alexandre Paulino DE SOUSA2 http://orcid.org/0000-0001-9568-3411Clécio GODEIRO-JUNIOR1 http://orcid.org/0000-0002-4312-16331Universidade Federal do Rio Grande do Norte, Hospital...
Background: Migraine is one of the most common disorders in neurological clinical practice and is part of the group of primary headaches. It often affects individuals in the age group of 25-55 years, when people are at their peak of economic productivity. Many patients ultimately overuse analgesics. Overuse is defined by the use of analgesics for at least 15 times a month...
LetterPost-COVID-19 Syndrome? New daily persistent headache in the aftermath of COVID-19Síndrome Pós-COVID-19? Nova cefaleia diária persistente após COVID-19Jonathan Wei Ting Wen Liu1 http://orcid.org/0000-0003-0388-4254Renata D'altoé de Luca1 http://orcid.org/0000-0001-7455-8208Heraldo Oliveira Mello Neto2 http://orcid.org/0000-0003-1307-5071Igor Barcellos1 http://orcid.org/0000...
Background:Central neuropathic pain (CNP) is often refractory to available therapeutic strategies and there are few evidence-based treatment options. Many patients with neuropathic pain are not diagnosed or treated properly. Thus, consensus-based recommendations, adapted to the available drugs in the country, are necessary to guide clinical decisions.Objective:To develop...
IMAGES IN NEUROLOGYHemorrhagic PRES: an unusual neurologic manifestation in two COVID-19 patientsPRES hemorrágica: uma manifestação neurológica incomum em dois pacientes com COVID-19Daniel Aguiar Dias1 http://orcid.org/0000-0002-9122-2770Lara Albuquerque de Brito2 http://orcid.org/0000-0002-6070-1808Luciana de Oliveira Neves2 http://orcid.org/0000-0002-8524-4308Roberto Guido...
IMAGES IN NEUROLOGYTransient lesion in the splenium of the corpus callosum associated with COVID-19Lesão transitória no esplênio do corpo caloso associada à COVID-19Felipe Araújo Andrade DE OLIVEIRA1 2 http://orcid.org/0000-0002-9583-3165Tiago Feitosa Bastos DE MELO1 http://orcid.org/0000-0002-5975-7804Pedro Augusto Sampaio ROCHA-FILHO2 http://orcid.org/0000-0001-5725-26371Real...
IMAGES IN NEUROLOGYAnti-Ri autoimmune encephalitis associated with breast cancerEncefalite autoimune Anti-Ri associada a câncer de mamaEuripedes Gomes de CARVALHO NETO1 http://orcid.org/0000-0002-5124-7877Matheus Ferreira GOMES1 http://orcid.org/0000-0002-4762-4510Ronnie Peterson Marcondes ALVES2 http://orcid.org/0000-0002-9369-1917Alexei Peter dos SANTOS3 http://orcid.org/0000...
Images in NeurologyWhite matter calcifications in infants: not always STORCHCalcificações na substância branca em recém-nascidos: nem sempre TORCHSFelipe Alba SCORTEGAGNA1 2 http://orcid.org/0000-0001-9088-2542Renato Hoffmann NUNES1 2 http://orcid.org/0000-0002-2483-964XLuiz Celso VILANOVA3 http://orcid.org/0000-0002-7631-0182Felipe Torres PACHECO1 2 http://orcid.org/0000-0002...