Epigenetics

Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC).

Alpha-linolenic acid-mediated epigenetic reprogramming of cervical cancer cell lines.

METTL14-mediated m(6)A modification of DDIT4 promotes its mRNA stability in aging-related idiopathic pulmonary fibrosis.

Poly-epigenetic scores for cardiometabolic risk factors interact with demographic factors and health behaviors in older US Adults.

Glucocorticoid receptor epigenetic activity in the heart.

TET-mediated 5hmC in breast cancer: mechanism and clinical potential.

SIRT1/DNMT3B-mediated epigenetic gene silencing in response to phytoestrogens in mammary epithelial cells.

Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure.

ANRIL upregulates TGFBR1 to promote idiopathic pulmonary fibrosis in TGF-β1-treated lung fibroblasts via sequestering let-7d-5p.

Homocysteine affects macrophage polarization by altering m6A methylation of scavenger receptors CD209 and CD163L1.

Epigenetic aging of semen is associated with inflammation.

Placental and immune cell DNA methylation reference panel for bulk tissue cell composition estimation in epidemiological studies.

Epigenome-wide association study of loneliness in a sample of U.S. middle-aged twins.

Epigenome-wide meta-analysis of prenatal vitamin D insufficiency and cord blood DNA methylation.

Parental arsenic exposure and tissue-specific DNA methylation in Bangladeshi infants with spina bifida.

Methylome profile of medaka eggs and sperm.

MK-801-exposure induces increased translation efficiency and mRNA hyperacetylation of Grin2a in the mouse prefrontal cortex.

Clinical significance of peripheral blood DDR1 and CtBP gene methylation detection in patients with acute pancreatitis.

Detection of DNA methylation from buccal swabs using nanopore sequencing to study stunting.

Implementation of the Methyl-Seq platform to identify tissue- and sex-specific DNA methylation differences in the rat epigenome.

Epigenomic annotations for the rat lag far behind those of human and mouse, despite the rat’s immense utility in pharmacological and behavioral studies and the need to understand their epigenetic mechanisms. We have designed a targeted-enrichment ...

PRKCB methylation: a potential biomarker of MDD with childhood chronic stress, a cross-sectional study in drug-naive, first-episode adolescent MDD.

The purpose of this study was to investigate the relationship between childhood chronic stress(CCS), Protein kinase C beta (PRKCB) methylation and adolescent major depressive disorder (MDD). After recruiting 100 adolescents with MDD and 50 healthy ...

An epigenetic human cytomegalovirus infection score predicts viremia risk in seropositive lung transplant recipients.

Cytomegalovirus (CMV) infection and reactivation in solid organ transplant (SOT) recipients increases the risk of viremia, graft failure and death. Clinical studies of CMV serostatus indicate that donor positive recipient negative (D[+] /R[−] ...

Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays.

A promising application of kidney-specific cell-free DNA methylation markers in real-time monitoring sepsis-induced acute kidney injury.

Sepsis-induced acute kidney injury (SI-AKI) is a common clinical syndrome that is associated with high mortality and morbidity. Effective timely detection may improve the outcome of SI-AKI. Kidney-derived cell-free DNA (cfDNA) may provide new insight ...

Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns.

Eastern and Western Finns show a striking difference in coronary heart disease-related mortality; genetics is a known contributor for this discrepancy. Here, we discuss the potential role of DNA methylation in mediating the discrepancy in cardiometabolic ...