Anamnez ve cinsel gelişim öyküsü alınır. • Hem gelişim öyküsünün alınması hem de ailenin tutumunun ve sürece olası katkılarının belirlenebilmesi için aileyle görüşme talep edilir. Görüşmeyi kabul eden ve gelebilen aile de görüşmede ve karar aşamasında yer alır. • Hasta psikotik bozukluk, ağır kişilik bozukluğu, bilişsel yetersizlik tanıları açısından değerlendirilir ve bu tanılar...
Gender Dysphoria is a condition that is characterized by incongruence between the experienced gender and the natal sex. They want to live and be accepted as a member of the other sex. Gender transitioning is the name given to the medical intervention that transforms a woman into a man or a man into a woman. Legal regulation regarding gender transitioning in our country is given...
In the treatment of sexual identity disorders, a series of surgeries are performed according to the need to change the body appearance and physical functions of the patients in order to obtain a similar appearance to the physical characteristics of the desired gender. It is necessary to have general information about these surgeries, to inform patients, to make treatment plans...
An increasing number of adolescents and adults present to clinics for medical assistance with gender dysphoria. The first evaluation of the patients presenting with this clinical picture with unclear etiology includes a short clinical examination to exclude various reproductive and endocrinological pathologies that may rarely cause this condition. This review aimed to provide an...
Gender identity is defined as the acceptation and perception of an individual’s body and identity within a certain gender. Individuals with gender dysphoria, as diagnosed by psychiatrists, should also be evaluated in terms of endocrinologic measures, and certain underlying conditions/diseases regarding gender dysphoria must be excluded. Prior to initiation of hormonal and...
Gender Dysphoria (GD) is a condition which is characterized by incongruence between the experienced gender and the natal sex at least for 6-months, which also causes deterioration of functionality. After psychiatric evaluations, medical treatment for adolescents with GD consists of 3-phases. The first phase is the suppression of puberty with GnRH analogues. In the second phase...
Gender dysphoria (GD) is defined as an apparent incongruence between assigned sex and experienced gender. Scholars across the world are attempting to achieve guidelines for a universal approach for children and adolescents experiencing GD. Recent studies have highlighted the importance of the biopsychosocial model as a holistic template for gender dysphoria. Youth with gender...
Gender Identity issues have been known and studied since the 19th century. Transsexuality was first included in the Diagnostic and Statistical Manual of Mental Disorders (DSM) III in 1980, and have been revised in the further versions. The prevalence of transsexuality and the women/men ratio is not to be found as a precise number. The numbers are various among different research...
Unintentional mistake in the ranking of authors’ names in the 23rd reference of the article published on page 397 in the 4th issue of the 83rd volume of the Journal of Istanbul Faculty of Medicine 2020 was realized. It is stated that the names of the authors in the reference should not be in the order of “Kesli R, Demir C”, but “Demir C, Kesli R”. The author of the published...
Urinary incontinence, anal incontinence, pelvic organ prolapse and sexual dysfunction are included in the definition of pelvic floor dysfunction. Pregnancy and childbirth play a major role in the emergence of pelvic floor dysfunction, which is seen in 41%-65% of women worldwide. Studies have suggested that childbirth causes damage to the pelvic floor due to damage to nerves...
Neurogenesis is a biological process characterized by the formation of new neurons. During embryogenesis, neural stem cells multiply, migrate, and differentiate into mature neurons that will eventually form the central nervous system. After proliferation, differentiation, and displacement, it has been proven that, during exercise, new neurons in the dentate gyrus settle in the...
The Coronavirus disease 19 (COVID-19) pandemic, which is the etiological agent of a severe acute respiratory syndrome- associated coronavirus (SARS-CoV-2), has influenced the whole world with the current and possible results. COVID-19 has very unique virological, clinical and immunological characteristics. In COVID19, immune responses can vary widely, ranging from responses that...
In approximately 30% of the patients who planned to undergo allogeneic stem cell transplantation, HLA-matched donors can be found from either siblings or related donors. For the remaining 70%, the source of healthy donor stem cells are provided by bone marrow or cord blood banks generated by the contribution of volunteer donors. Each country registers the HLA phenotype data of...
Glioblastoma is the most common poor prognosis brain tumor in adults. Although neurological signs are often seen as first symptoms at clinical course of GBM, pychiatric symptoms also accompany the presentation. Mood and personality changes, anxiety and psychosis are the most common psychiatric symptoms in presentation of GBM. In this article, a 57-year-old man admitted to...
Clarithromycin and azithromycin are the most frequently prescribed oral macrolide antibiotics for children. Macrolides are relatively safe antibiotics due to their low allergenicity, but are nevertheless known to cause hypersensitivity reactions. Azithromycin appears to be responsible for severe reactions more often than clarithromycin. The most common reactions are maculopapular...
Hidradenoma papilliferum (HP) is a rare, small, benign, cystic, papillary, slow growing tumour arising from the apocrine gland in the anogenital region of adult women. A 54-year-old patient had an asymptomatic nodule in the vulvar region for 3 months. Approximately a 1x1.5 cm nodular formation was observed on the left labium minus. In the pathological examination of the tissue...
Objective: Myelitis is a monophasic inflammatory demyelinating disease of the spinal cord and brain, often of unknown origin. It is characterized with motor, sensory, and autonomic symptoms. In the childhood age group, it is most frequently seen as acute disseminated encephalomyelitis (ADEM) and transverse myelitis. In this study, the patients who presented to our clinic with...
Objective: This study aimed to examine the levels of distress and alexithymia and the relationship between these two variables in individuals diagnosed with hematological cancer. Material and Method: This descriptive study was conducted between February and June 2018 with 135 individuals between the ages of 18 and 65 who were diagnosed with hematological cancer, who were...
Objective: Our study was performed on 49 chronic lymphocytic leukemia (CLL) patients followed in the outpatient clinic of the Istanbul University Cerrahpasa Medical Faculty Department of Hematology. We aimed to analyze the relationship between autoimmune phenomena and CLL. Methods: Twenty-five CLL patients with and 24 CLL patients without autoimmune phenomenon were included...
Objective: Impaired physical growth is one of the prolonged effects of deficient iodine, a micronutrient. Thus, this study aimed to determine the relationship between the urinary iodine levels and anthropometric indices in a population of schoolchildren in Ilorin, North-Central Nigeria. Material and Method: This was a cross-sectional analytical study carried out among primary...
Objective: Pulse wave velocity (PWV) is frequently used for arterial stiffness assessment in chronic renal disease (CRD). There are very few studies in the literature about the relationship between arterial stiffness and renal progression leading to mortality in CRD. Herein, we searched the relationship between arterial stiffness, and progression of kidney disease, leading to...
Objective: We examined the serum uric acid (UA) levels among patients with sleep-related breathing disorders (SRBD) and the relationship between UA levels and obstructive sleep apnea (OSA) severity, nocturnal hypoxemia (NH) and obesity hypoventilation syndrome (OHS). Material and Method: Subjects with body mass index (BMI) ≥30 kg/m2 who, according to polysomnography results, have...
Objective: In this experimental work, we aimed to compare the efficacy of two different methods of combining the mucoperiosteal flaps in an animal model: using a tissue adhesive material N-butyl-2-cyanoacrylate (Glubran®2) and the classical suturing technique in cleft palate surgery. Methods: Rats were separated into group A and B. In group A (n=12) mucoperiosteal flaps were...
Objective: Our objective was to assess the patients who have probable early stage ovarian cancer. Materal and Method: Between 2010-2018, 208 patients with isolated adnexal masses who underwent surgery due to presumed malignancy were analyzed. We excluded patients with radiologic evidence of ascites and tumour implants. Results: According to the final pathology reports, 52 (25...
Objective: Holoprosencephaly (HPE, #MIM 236100) is the most common developmental defect of midline cleavage in the human forebrain. Environmental, genetic, and multifactorial causes are involved in its etiology. About half of the cases have chromosome aberrations such as trisomies 13 and 18, triploidy and structural imbalances. Single gene mutations have been shown in ~25% of...