To (a) investigate patterns of structural damage in flexed, healthy ovine lumbar motion segments subjected to controlled impact loading approximating a low energy traumatic fall; and (b) determine the relative risk of herniation, endplate failure and other subtle modes of structural disruption as potential mechanical initiators of disc degeneration. Twenty-three healthy ovine...
Kummell’s disease (KD) is a long-term complication of vertebral compression fractures, resulting in vertebral collapse and kyphosis. Despite its clinical significance, the underlying mechanisms remain poorly understood. To identify the predictive factors for the onset of KD and provide clinical insights for early screening and intervention in KD patients. Retrospective study. A...
Individuals with low back pain (LBP) often exhibit balance impairments resulting from altered neuromuscular control and sensory integration deficits. This study aimed to compare differences in sway excursion and neuromuscular responses in maintaining spatial orientation and equilibrium between adults with and without LBP under eyes-open and eyes-closed conditions. Thirty-two...
Multiple myeloma (MM), a type of B-cell non-Hodgkin lymphoma, frequently causes osteolytic spinal lesions, increasing the risk of fracture and poor sagittal spinopelvic alignment. In relapsed patients, these changes may contribute to increased pain and functional impairment. The clinical data of 86 MM patients (48 males, 38 females) who underwent ≥ 3 whole-body CT scans between...
The rising incidence of spondylodiscitis (SD) poses a challenge to healthcare systems worldwide. Treatment approaches are inconsistent, devoid of standardized algorithms and lack evidence-based guidelines. To date there is a knowledge gap relative to treatment, readmission rates and efficacy for different SD management strategies. This study aims to assess the 90-day all-cause...
To evaluate the responsiveness and the minimal important change (MIC) of Neck Disability Index (NDI) and pain during activity by the numeric rating scale (NRSa) in the Norwegian neck and back registry (NNRR). Participants with neck pain responding to baseline, 6 and 12-months follow-up in the NNRR were included. Responsiveness was calculated using the area under the receiver...
This study aimed to determine whether there are differences in plantar pressures during gait between patients with lumbar disc herniation -induced sciatica and healthy individuals. This observational case–control study included 41 patients with sciatica due to lumbar disc herniation and 30 healthy controls. Plantar pressures were evaluated using the FootScan® platform in 10-foot...
Metastatic intramedullary spinal cord tumors generally have poor prognosis, with chemotherapy often deemed ineffective. We report about a patient who achieved a favorable outcome with an immune checkpoint inhibitor following the resection of the extramedullary component of a metastatic intramedullary tumor. A 74-year-old man underwent upper lobectomy for lung cancer. Seven months...
Although previous studies have indicated a potential association between the gut microbiota and intervertebral disc degeneration (IVDD), the precise nature of this relationship remains unclear. The objective of this study is to further explore the potential causal relationship between gut microbiota and IVDD using a bidirectional Mendelian randomization approach, with the aim of...
Symptomatic lumbar spondylolisthesis is usually treated with fusion surgery when conservative methods fail. However, traditional open decompression and fusion involves a large skin incision and muscle detachment. Therefore, minimally invasive techniques have been developed to reduce tissue damage, potentially leading to less postoperative pain and earlier resumption of activities...
When nonsurgical treatments for low back pain with radiculopathy fail to relieve symptoms from nerve root compression, lumbar spine fusion is the standard treatment. A potential new option is using a vertebral body osteotomy (VBO) with the Vertiwedge Intraosseous System™, a novel spinal implant designed to restore foraminal height, spinal alignment, and preserve motion. The...
Treatment of preoperative depression has been shown to reduce pain perception and disability after spine surgery, which encouraged utilizing antidepressants as a treatment for pain. Though opioid consumption after spine surgery has been well studied, few studies have investigated its association with medications such as antidepressants and gabapentinoids. Therefore, our study...
The purpose of this study was to investigate the association between antidepressant use and inpatient physical therapy performance, as well as discharge disposition after surgery. Patients undergoing primary 1–3 level lumbar fusion at a single, tertiary care institution from 2017 to 2021 were retrospectively identified. Patient characteristics, surgical details, and surgical...
Cervical orthoses are widely used in the management of cervical spine (c-spine) injuries, serving to limit motion, alleviate pain, and enhance patient security. While extensive research has examined soft and rigid cervical braces, data on semi-rigid braces, such as the PDC collar, remain scarce. This study aims to compare the immobilizing effects of a semi-rigid cervical orthosis...
The Dubousset Functional Test (DFT) has precise metrics that evaluate the functionality of the spinopelvic muscle groups maintaining the spinal alignment. This study investigates concurrent validity, interrater reliability, responsivity, and feasibility of the DFT in patients with thoracic hyperkyphosis. Thirty patients with thoracic hyperkyphosis performed the DFT twice, the...
To identify and characterize randomized controlled trials investigating the effectiveness of physiotherapy (PT) after cervical spine surgery in patients with degenerative spinal disease in terms of the effect of PT, and to define the treatment parameters included in the PT program and the initial period, duration, and frequency of these parameters. PubMed, Scopus, Cochrane...
Sacral surgeries, especially sacrectomies, are complex due to the sacrum’s anatomical intricacies and its proximity to vital neurovascular structures. These procedures are primarily performed for the treatment of primary sacral malignancies, metastatic lesions, and traumatic injuries. Infection is a significant concern in sacrectomies, given the large incisions, extensive soft...
Vertebral Body Tethering (VBT) allows correction of scoliosis while preserving the spinal mobility. Despite an increasing availability of data on clinical experience and surgical techniques, there is still a lack of knowledge on the underlying biomechanics, specifically when considered in combination with growth. Therefore, the purpose of this study is to develop a growing...
The relationship between pain experience and biomechanical impairment in chronic low back pain (LBP) is unclear. Among the broader pain literature, sex-based differences in pain experience have been established. However, it is unknown if sex-based differences in pain experience relates to compromised movement patterns for patients with chronic LBP. This study examined sex...
The clinical issue of lumbosacral metastases (LM) is really significant. This study aims to compare in patients with lumbar pathology (LM) the outcomes of the conventional iliac (CI) screw technique against the S2 alar-iliac (S2AI). A retrospective review of institutional databases was performed for lumbar metastasis patients. who underwent lumbopelvic fixation, with or without...
Adolescent Idiopathic Scoliosis negatively impacts chest wall development. Bracing and fusion surgery have shown varied effects on pulmonary outcomes. Vertebral Body Tethering presents a growth-sparing alternative that might mitigate these effects by reducing biomechanical disruptions. Aim was to evaluate changes in pulmonary functions during the course of the follow-up after VBT...