How whole-body vibration can help our COPD patients. Physiological changes at different vibration frequencies

International Journal of COPD Dovepress open access to scientific and medical research Original Research International Journal of Chronic Obstructive Pulmonary Disease downloaded from https://www.dovepress.com/ by 88.198.20.149 on 06-May-2021 For personal use only. Open Access Full Text Article How whole-body vibration can help our COPD patients. Physiological changes at different vibration frequencies This article was published in the following Dove Press journal: International Journal of COPD Eulogio Pleguezuelos 1–3 Paula Casarramona 1 Lluis Guirao 1,3 Beatriz Samitier 1 Pilar Ortega 4 Xavier Vila 4 Amin Del Carmen 1 Laura Ovejero 4 Eva Moreno 5 Noemi Serra 5 Manuel Gomís 3 Manuel V GarnachoCastaño 3 Marc Miravitlles 6 Physical Medicine and Rehabilitation Department, Mataró Hospital, Barcelona, Spain; 2Department of Experimental Science and Healthcare, Faculty of Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain; 3 School of Sciences, TecnocampusSchool of Health Sciencies, Pompeu Fabra University, Mataro, Barcelona, Spain; 4Pneumology Department, Mataró Hospital, Barcelona, Spain; 5 Physical Medicine and Rehabilitation Department, Hospitalet General Hospital, L’Hospitalet de Llobregat, Barcelona, Spain; 6Pneumology Department, Hospital Universitari Vall d’Hebron, Ciber de Enfermedades Respiratorias (CIBERES), Barcelona, Spain 1 Correspondence: Eulogio Pleguezuelos Hospital de Mataró, c/ Cirera s/n, 08302. Mataro, Barcelona, Spain Tel +34 93 741 7728 Fax +34 93 741 7717 Email Introduction Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition that is often associated with multiple comorbidities.1 Among the extrapulmonary manifestations, skeletal muscle weakness and emaciation are frequent and are associated with exercise intolerance and health status deterioration in COPD patients, regardless of the level of airway obstruction.2 Skeletal muscle dysfunction in COPD is characterized by a significant reduction in muscle force and resistance, which may be secondary to multiple mechanisms.3 This dysfunction may appear in relatively early phases of the disease and impair the symptoms and quality of life of patients.4,5 In recent years, there has been increasing interest in whole-body vibration training (WBVT) as a form of exercise, especially among the elderly.6,7 WBVT is done on a platform that generates vertical sinusoidal vibrations, which stimulate muscle spindles and produce muscular contractions similar to tonic reflexes.8 3373 submit your manuscript | www.dovepress.com International Journal of COPD 2018:13 3373–3380 Dovepress © 2018 Pleguezuelos et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). http://dx.doi.org/10.2147/COPD.S165058 Powered by TCPDF (www.tcpdf.org) Objective: Evaluate cardiac, metabolic, and ventilatory changes during a training session with whole-body vibration training (WBVT) with 3 different frequencies in patients with chronic obstructive pulmonary disease (COPD). Methods: This was a prospective, interventional trial in outpatients with severe COPD. Participants performed 3 vertical WBVT sessions once a week using frequencies of 35, 25 Hz and no vibration in squatting position (isometric). Cardiac, metabolic, and ventilator parameters were monitored during the sessions using an ergospirometer. Changes in oxygen pulse response (VO2/HR) at the different frequencies were the primary outcome of the study. Results: Thirty-two male patients with a mean forced expiratory volume in 1 second of 39.7% completed the study. Compared to the reference of 35 Hz, VO2/HR at no vibration was 10.7% lower (P=0.005); however, no statistically significant differences were observed on comparing the frequencies of 35 and 25 Hz. The median oxygen uptake (VO2) at 25 Hz and no vibration was 9.43% and 13.9% lower, respectively, compared to that obtained at 35 Hz (both comparisons P,0.0001). The median expiratory volume without vibration was 9.43% lower than the VO2 at the end of the assessment at 35 Hz vibration (P=0.002). Conclusion: Vertical WBVT training sessions show greater cardiac, metabolic, and respiratory responses compared with the squat position. On comparing the 2 frequencies used, we observed that the frequency of 35 Hz provides higher cardiorespiratory adaptation. Keywords: COPD, cardioventilatory response, exercise, whole-body vibration Dovepress International Journal of Chronic Obstructive Pulmonary Disease downloaded from https://www.dovepress.com/ by 88.198.20.149 on 06-May-2021 For personal use only. Pleguezuelos et al Gloeckl et al9 were the first to publish improvements in the 6-minute walk test (6MWT) and sit-to-stand test in a COPD population following WBVT. Later, our group concluded that treatment with WBVT for 6 weeks increased functional capacity measured by the 6MWT but did not improve the strength of knee flexors and extensors assessed by an isokinetic test.10 An interesting result of our study was the reduction in oxygen saturation and a mean increase in heart rate during the course of vertical WBVT with 33 Hz.10 However, it was not clear whether the answers were dependent on the frequency of the vibration. To date, few studies have described cardiac and ventilatory physiological changes during WBVT sessions, and those that are available have conflicting results that may not be fully explained by differences in the protocol.10–12 Therefore, the current study was designed with the main objective of evaluating cardiac and ventilatory changes during a training session with the WBVT at 3 different frequencies in a severe COPD population in order to identify the optimal frequency for training in this population. Methods Study design and population This prospective, interventional trial was conducted to determine the changes in cardiac and ventilatory parameters during a WBVT session at different treatment frequencies. Patients referred to the Physical Medicine and Rehabilitation Department of the Hospital of Mataró (Barcelona, Spain) from September 2016 to May 2017 were included if they fulfilled the following inclusion criteria: severe COPD defined as a postbronchodilator forced expiratory volume in 1 second/ forced vital capacity (FEV1/FVC) ,0.7 and FEV1,50% predicted and stable disease defined as no exacerbation, and hospital admission or change in treatment in the previous 3 months. The exclusion criteria were oth (...truncated)