Correction for: Ganglioside GD1a enhances osteogenesis by activating ERK1/2 in mesenchymal stem cells of Lmna mutant mice.

Aging (Albany NY). 2023 Jan 15; 15(1): 288–289. Published online 2023 Jan 14. doi: 10.18632/aging.204489 PMCID: PMC9876646 PMID: 36641777 Correction for: Ganglioside GD1a enhances osteogenesis by activating ERK1/2 in mesenchymal stem cells of Lmna mutant mice Dong Hoon Kwak, 1 , 2 Ji Hye Park, 1 , 2 Eul Sig Choi, 1 , 2 Seong Hyun Park, 1 , 2 Seo-Yeon Lee, 1 , 2 and Seoul Lee 1 , 2 Dong Hoon Kwak 1Department of Pharmacology, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea 2Brain Research Institute, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea Find articles by Dong Hoon Kwak Ji Hye Park 1Department of Pharmacology, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea 2Brain Research Institute, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea Find articles by Ji Hye Park Eul Sig Choi 1Department of Pharmacology, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea 2Brain Research Institute, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea Find articles by Eul Sig Choi Seong Hyun Park 1Department of Pharmacology, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea 2Brain Research Institute, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea Find articles by Seong Hyun Park Seo-Yeon Lee 1Department of Pharmacology, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea 2Brain Research Institute, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea Find articles by Seo-Yeon Lee Seoul Lee 1Department of Pharmacology, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea 2Brain Research Institute, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea Find articles by Seoul Lee Author information Article notes Copyright and License information Disclaimer 1Department of Pharmacology, School of Medicine, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea 2Brain Research Institute, Wonkwang University, Iksan, Jeollabuk-do 54538, Republic of Korea Corresponding author. Correspondence to: Seoul Lee; email: Received 2022 Dec 26; Accepted 2023 Jan 12. Keywords: Lmna, mesenchymal stem cells, osteogenesis, GD1a, aging Copyright : © 2023 Kwak et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This corrects the article "Ganglioside GD1a enhances osteogenesis by activating ERK1/2 in mesenchymal stem cells of Lmna mutant mice" in volume 14 on page 9445. This article has been corrected: The authors found that Western blot images of p-ERK1/2 and ERK1/2 in Figure 4F were from different experiment with protein extracts from LmnaDhe/+mice. They replaced the incorrect images with the images of p-ERK1/2 and ERK1/2 in MSC protein extracts from normal and Lamin A/C knockdown (KD) mice. In Figure 4H, the authors corrected a typo where “p-ERK1/2” was mislabeled “p-REK1/2”. The authors also revised the Figure legend for Figure 4F and 4G as follows: “(F) Lamin A/C was knocked down in mouse MSCs using siRNA. (G) Primary MSCs with LmnaDhe/+ mutation were isolated from LmnaDhe/+ mice.” These corrections have no impact on the experimental outcome or conclusions. Corrected Figure 4 legend and panels 4F and 4G presented below. Open in a separate window Figure 4 Increases of osteogenesis and ERK1/2 activation in GD1a-treated Lmna dysfunction MSCs. … dysfunction MSCs. (F) Lamin A/C was knocked down in mouse MSCs using siRNA. (G) Primary MSCs with LmnaDhe/+ mutation were isolated from LmnaDhe/+ mice. (H) Phosphorylation of ERK1/2 in Lmna dysfunction MSCs treated with GD1a. (I)…. Phosphorylation of ERK1/2 was determined by western blotting with anti-p-ERK1/2. ERK1/2 was used as a loading control. Values represent mean ± SD; &&&p < 0.001 indicates a significant difference from the normal MSCs; ***p < 0.001 indicates a significant difference from the LmnaDhe/+ mutant MSCs; ###p < 0.001 indicates a significant difference from the Lamin A/C KD MSCs. $$$p < 0.001 indicates a significant difference from the U0126-treated MSCs. Articles from Aging (Albany NY) are provided here courtesy of Impact Journals, LLC (...truncated)